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The map label for this gene is 103486495

Identifier: 103486495

GI number: 103486495

Start: 1030487

End: 1031716

Strand: Reverse

Name: 103486495

Synonym: Sala_1006

Alternate gene names: NA

Gene position: 1031716-1030487 (Counterclockwise)

Preceding gene: 103486496

Following gene: 103486494

Centisome position: 30.84

GC content: 64.72

Gene sequence:

>1230_bases
ATGGCAAAGGATGTTTTCGTTCTCGGCGGCGCGCAGAGCGACTTTTCGCGTAACATCGAGCGCGAGGGCGGTGGGATGTT
CGAACTGTTCCGCGACGTCGCGGAGGCGGCTTTTGCCGCCACGGGCATTGAACCAAGGGAAGTCGAAACGGCGCATGTCG
GCAATTTCGTGGGCGAGCTGTTCGCGGGGCAAGGGCAGCTCGGCGGTTTCTTCGGCCACGTCCATCCCGACCTCGCGGGC
GTCCCGGCGTCGCGGCACGAGGCGGCTTGCGCGTCGGGCAGCATCGCCATCCTTGCCGCCGCGGCGGAGATCGAGGCCGA
GCGCTATGGACTCGCGCTCGTGCTCGGGATCGAGCTGATGCGCAACGTTCCGGGCCAGCGCGCCGCCGAATATCTCGGCG
CCGCTGCCTGGGCAGGCCGCGAGGCGCAGGAGGCGCGCTATCTGTGGCCGTCCATGTTCGCGCGCGTTGCCGAGGAATAT
GAGGAACGCTTCGGGCTCGACCGCGCCCATCTGCGCGCGATTTCGGCCAATAATTTCGCCAATGCGAAAAAAAACCCCAA
TTCGCAGACGCGCGGCTGGGCGATCACCGAGGCGCATCTGGACGAGAATGACGAGGTCAATCCGTTGATCGAGGGACGTC
TGCGCAAGTCCGATTGCGGTCAGGTCACCGACGGGGCGGCGGCGGTTTTCCTTGCTTCGGCCGAAATTGCCGAACGTTAC
GCGCAGCGTCGGGGCATTCCGATCGACACCATCCCGCGCATCAAGGGCTGGGGCCATTCGACCGCGCCCCTGCTCTATTC
GACAAAGATTCAGAACAGTCGCGGCCAAGATTTTGTTTTTCCTGGCGTTCGCAAGGCGATGATGGACGCGTTGCGGCGAG
CGGAGATGCCCGACGTTTACGCCTGTGACGGGGTCGAGGTGCATGACTGTTTCTCGATCACCGAATATATGGCGATCGAC
CATTTCGGGATCACCAAACCGGGCGAAAGCTGGCGCGCGGTCGAGGACGGGACGATTGCGCTGGGCGGCAGGCTGCCGGT
CAACCCGTCGGGCGGGCTGATCGGCCTTGGCCACCCGGTCGGCGCGACCGGGGTTCGGATGCTGCTGGACAGCTGGCGGC
AAGTCACCGGAAACGCTGGCGATTATCAGGTGGAAGGGGCGCGCAATTTCGCCACCTTCAACGTCGGCGGCAGCGCGACA
ACCGCGGTCAGCTTCGTCGTCGGCACCTGA

Upstream 100 bases:

>100_bases
CGGGGCGGGGGCCATCGGCCTTGTGCAAGGTTGCGAGCCCCCACCCCAACCCCTCCCCTGAAGGGGAGGGGCCTTATCGA
ACTCGAAAAGGAAGCCTGAC

Downstream 100 bases:

>100_bases
TTTGGCGGACGTCTTTCTCTATGACGCCGTCCGCACGCCACGCGGCAAGGCACGGCCCGACGGCGGGCTCGCGAACCTCA
GCCCGCAGGAACTGGTGCGC

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAKDVFVLGGAQSDFSRNIEREGGGMFELFRDVAEAAFAATGIEPREVETAHVGNFVGELFAGQGQLGGFFGHVHPDLAG
VPASRHEAACASGSIAILAAAAEIEAERYGLALVLGIELMRNVPGQRAAEYLGAAAWAGREAQEARYLWPSMFARVAEEY
EERFGLDRAHLRAISANNFANAKKNPNSQTRGWAITEAHLDENDEVNPLIEGRLRKSDCGQVTDGAAAVFLASAEIAERY
AQRRGIPIDTIPRIKGWGHSTAPLLYSTKIQNSRGQDFVFPGVRKAMMDALRRAEMPDVYACDGVEVHDCFSITEYMAID
HFGITKPGESWRAVEDGTIALGGRLPVNPSGGLIGLGHPVGATGVRMLLDSWRQVTGNAGDYQVEGARNFATFNVGGSAT
TAVSFVVGT

Sequences:

>Translated_409_residues
MAKDVFVLGGAQSDFSRNIEREGGGMFELFRDVAEAAFAATGIEPREVETAHVGNFVGELFAGQGQLGGFFGHVHPDLAG
VPASRHEAACASGSIAILAAAAEIEAERYGLALVLGIELMRNVPGQRAAEYLGAAAWAGREAQEARYLWPSMFARVAEEY
EERFGLDRAHLRAISANNFANAKKNPNSQTRGWAITEAHLDENDEVNPLIEGRLRKSDCGQVTDGAAAVFLASAEIAERY
AQRRGIPIDTIPRIKGWGHSTAPLLYSTKIQNSRGQDFVFPGVRKAMMDALRRAEMPDVYACDGVEVHDCFSITEYMAID
HFGITKPGESWRAVEDGTIALGGRLPVNPSGGLIGLGHPVGATGVRMLLDSWRQVTGNAGDYQVEGARNFATFNVGGSAT
TAVSFVVGT
>Mature_408_residues
AKDVFVLGGAQSDFSRNIEREGGGMFELFRDVAEAAFAATGIEPREVETAHVGNFVGELFAGQGQLGGFFGHVHPDLAGV
PASRHEAACASGSIAILAAAAEIEAERYGLALVLGIELMRNVPGQRAAEYLGAAAWAGREAQEARYLWPSMFARVAEEYE
ERFGLDRAHLRAISANNFANAKKNPNSQTRGWAITEAHLDENDEVNPLIEGRLRKSDCGQVTDGAAAVFLASAEIAERYA
QRRGIPIDTIPRIKGWGHSTAPLLYSTKIQNSRGQDFVFPGVRKAMMDALRRAEMPDVYACDGVEVHDCFSITEYMAIDH
FGITKPGESWRAVEDGTIALGGRLPVNPSGGLIGLGHPVGATGVRMLLDSWRQVTGNAGDYQVEGARNFATFNVGGSATT
AVSFVVGT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=417, Percent_Identity=27.0983213429257, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI302344767, Length=344, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI302344760, Length=344, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI302344762, Length=333, Percent_Identity=27.3273273273273, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI55956775, Length=288, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=401, Percent_Identity=24.9376558603491, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI19921506, Length=402, Percent_Identity=25.8706467661692, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24585051, Length=415, Percent_Identity=25.5421686746988, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 43844; Mature: 43712

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDVFVLGGAQSDFSRNIEREGGGMFELFRDVAEAAFAATGIEPREVETAHVGNFVGEL
CCCCEEEEECCCCHHHHCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCHHHHHHHHHHHH
FAGQGQLGGFFGHVHPDLAGVPASRHEAACASGSIAILAAAAEIEAERYGLALVLGIELM
HCCCCCCCCEECCCCCCCCCCCCCCCHHHHCCCCEEEEEEHHHHHHHHHCCHHHHHHHHH
RNVPGQRAAEYLGAAAWAGREAQEARYLWPSMFARVAEEYEERFGLDRAHLRAISANNFA
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCC
NAKKNPNSQTRGWAITEAHLDENDEVNPLIEGRLRKSDCGQVTDGAAAVFLASAEIAERY
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
AQRRGIPIDTIPRIKGWGHSTAPLLYSTKIQNSRGQDFVFPGVRKAMMDALRRAEMPDVY
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
ACDGVEVHDCFSITEYMAIDHFGITKPGESWRAVEDGTIALGGRLPVNPSGGLIGLGHPV
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCCCCCCEEECCCCC
GATGVRMLLDSWRQVTGNAGDYQVEGARNFATFNVGGSATTAVSFVVGT
CHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
AKDVFVLGGAQSDFSRNIEREGGGMFELFRDVAEAAFAATGIEPREVETAHVGNFVGEL
CCCEEEEECCCCHHHHCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCHHHHHHHHHHHH
FAGQGQLGGFFGHVHPDLAGVPASRHEAACASGSIAILAAAAEIEAERYGLALVLGIELM
HCCCCCCCCEECCCCCCCCCCCCCCCHHHHCCCCEEEEEEHHHHHHHHHCCHHHHHHHHH
RNVPGQRAAEYLGAAAWAGREAQEARYLWPSMFARVAEEYEERFGLDRAHLRAISANNFA
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCC
NAKKNPNSQTRGWAITEAHLDENDEVNPLIEGRLRKSDCGQVTDGAAAVFLASAEIAERY
CCCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHH
AQRRGIPIDTIPRIKGWGHSTAPLLYSTKIQNSRGQDFVFPGVRKAMMDALRRAEMPDVY
HHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
ACDGVEVHDCFSITEYMAIDHFGITKPGESWRAVEDGTIALGGRLPVNPSGGLIGLGHPV
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCCCCCCEEECCCCC
GATGVRMLLDSWRQVTGNAGDYQVEGARNFATFNVGGSATTAVSFVVGT
CHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]