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The map label for this gene is hmrR2 [H]

Identifier: 103486482

GI number: 103486482

Start: 1018327

End: 1018740

Strand: Reverse

Name: hmrR2 [H]

Synonym: Sala_0993

Alternate gene names: 103486482

Gene position: 1018740-1018327 (Counterclockwise)

Preceding gene: 103486485

Following gene: 103486480

Centisome position: 30.45

GC content: 67.63

Gene sequence:

>414_bases
ATGAAAATCGGCGAGCTGTCGCGTGCCACCGGCACCAACATCGAAACCATCCGCTATTATGAGCGCATCGGCCTGCTTCC
CGCGCCCGCGCGCACCGCGGGCAATTACCGCAGCTATGGCGACGCGCACCGCGCGCGGCTCCGCTTCGTGCGCCATTCGC
GCGAACTGGGCTTTACCATCGAGGAGATCCGCTCGCTGCTCGACCTGTCCGACGATCCCGCGCGCGATTGCGGCGAGGCC
GACCGCATCGCGACGCGGCATCTGAACCAAGTGGAAGCGAAGATTGCGCAGCTCACCCTGCTGCGCGACGAACTCAAGCG
CATCGTCGGGCGCTGCCGCGGCGGCGTCGCCGCCGACTGCCGCGTGATCGAGGCGCTGGGCGACCATCGCCACTGCGAAA
GCGCGCACATCTGA

Upstream 100 bases:

>100_bases
CCGCTTTTGCCGGCACAGCATCGATCGGCCATCGTCAAAGCTCCTTGGTCTTTCGAATCGGCACCCCATATGCACCCTGC
ATCAACTACAGGGTCAAGCG

Downstream 100 bases:

>100_bases
GGGATAAACGGCACCGGCGCGCCCCCCATCCGACCTCCCTGACGATAGTAGCCTATGGGAGGTCGGGTGGGGGAGCGGGC
CGGTGCCGCATCCGGCGTCA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MKIGELSRATGTNIETIRYYERIGLLPAPARTAGNYRSYGDAHRARLRFVRHSRELGFTIEEIRSLLDLSDDPARDCGEA
DRIATRHLNQVEAKIAQLTLLRDELKRIVGRCRGGVAADCRVIEALGDHRHCESAHI

Sequences:

>Translated_137_residues
MKIGELSRATGTNIETIRYYERIGLLPAPARTAGNYRSYGDAHRARLRFVRHSRELGFTIEEIRSLLDLSDDPARDCGEA
DRIATRHLNQVEAKIAQLTLLRDELKRIVGRCRGGVAADCRVIEALGDHRHCESAHI
>Mature_137_residues
MKIGELSRATGTNIETIRYYERIGLLPAPARTAGNYRSYGDAHRARLRFVRHSRELGFTIEEIRSLLDLSDDPARDCGEA
DRIATRHLNQVEAKIAQLTLLRDELKRIVGRCRGGVAADCRVIEALGDHRHCESAHI

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=128, Percent_Identity=38.28125, Blast_Score=94, Evalue=3e-21,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=33.8582677165354, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15435; Mature: 15435

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGELSRATGTNIETIRYYERIGLLPAPARTAGNYRSYGDAHRARLRFVRHSRELGFTI
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
EEIRSLLDLSDDPARDCGEADRIATRHLNQVEAKIAQLTLLRDELKRIVGRCRGGVAADC
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RVIEALGDHRHCESAHI
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKIGELSRATGTNIETIRYYERIGLLPAPARTAGNYRSYGDAHRARLRFVRHSRELGFTI
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
EEIRSLLDLSDDPARDCGEADRIATRHLNQVEAKIAQLTLLRDELKRIVGRCRGGVAADC
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RVIEALGDHRHCESAHI
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]