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The map label for this gene is ccpA [H]

Identifier: 103486410

GI number: 103486410

Start: 932756

End: 933811

Strand: Direct

Name: ccpA [H]

Synonym: Sala_0920

Alternate gene names: 103486410

Gene position: 932756-933811 (Clockwise)

Preceding gene: 103486409

Following gene: 103486411

Centisome position: 27.88

GC content: 62.97

Gene sequence:

>1056_bases
ATGGCGAGACGCCGCCAGGCGGTGACGATCAAGCATGTGGCGGCCGATGCCGGTGTGTCGCTGCAAACGGTCAGCCGTGT
GATCAACGACGAACCCAATGTGCGCTCGGCAATGAAGGCGCGCGTCCAGGCGTCCATCGACAAGCTCGGCTATGTGCCGT
CGATTGCCGCCCGCCGGATGAGCGGGTCGCGCTCTTATCTGATTCTGGCGATCAACGATCGCGACCGGACGATCGCGGAC
TGGACGGCGCGGCAGGGCACCGATTGGGTCGACCAGATGCTGCTGGGCGGCATGCTCAAGTGCGCCGAATATGGCTATCG
GCTTATTTTTGAGCTTGTCGACACGCACAGCGACCATGTCGAACGCGAACTGCGCGCAACCATCGCGGCGCTTCAGCCCG
ACGGCGTGATTCTGACGCCCCCCCATTCCGACAATCCGCTGATCGTGCGATTGCTTGAACGGCAGCGAATACCCTTTGCG
CGCATCGGATCGCGCGGCGGAGGGGCGGGGATTGCGCTGGTGATGGATGACGAGAGCATGGCGCGCCACGCGACGCGTCA
CCTCATCGACCTTGGCCATCGGCGCATTGCTTTCATTGCAGGTTCAAGCGAATATCCGCTGAGCCAATGGCGCGTCGATG
GTTGGGAAAGCGAAATGCGTGCCGCGGGATTGCCGACCGCCGGACTCGTGGCGAGAGGCGACTTCACTTACGAATCGGGC
GCGGCCGCCACGCGGCAGCTTCTTGGTCATCCGGATCGCCCTTCGGCGATCATCGCCAGCAATGACCAGATGGCGCTCGC
CGCGCTCGAAGTCGCGCGCGAACTGGGGATCGAGATTCCGTCACAGCTTTCGCTCGTAAGTTTCGACAATACGCCGATCG
TGCGTTTTACCCAGCCGACGCTTACCGCCGTTGATCAGCCGGTCGCCGAAACCGTGTCGCGCGCCGTCGAAATGATCATC
AAGGCGCAGCGGGGGGAAAAGTTGCCGCCACAACCCGTGATTGTTGCCGGGGGCTTCGTCGAACGCGAATCGACTTCTGC
GCCCGCGCATGGATGA

Upstream 100 bases:

>100_bases
TCCCAAGCGCATGGAGGTCGATTGGGTTCGGGTCTGGCAAAAAGGCGGGCCAGGAATTAGCCCCGCGATCGGCCAGGCGG
CGGAAAGGGGCGAATAGCAA

Downstream 100 bases:

>100_bases
TCCCGCGCCGCATCGGCACCAGTCGCTCGCTTTCATGCTGCTCTATGCCTTGGCGGTAGCTGGCGGAAGCATGGCCTATG
TCCCGTTCCTGACCATCCTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MARRRQAVTIKHVAADAGVSLQTVSRVINDEPNVRSAMKARVQASIDKLGYVPSIAARRMSGSRSYLILAINDRDRTIAD
WTARQGTDWVDQMLLGGMLKCAEYGYRLIFELVDTHSDHVERELRATIAALQPDGVILTPPHSDNPLIVRLLERQRIPFA
RIGSRGGGAGIALVMDDESMARHATRHLIDLGHRRIAFIAGSSEYPLSQWRVDGWESEMRAAGLPTAGLVARGDFTYESG
AAATRQLLGHPDRPSAIIASNDQMALAALEVARELGIEIPSQLSLVSFDNTPIVRFTQPTLTAVDQPVAETVSRAVEMII
KAQRGEKLPPQPVIVAGGFVERESTSAPAHG

Sequences:

>Translated_351_residues
MARRRQAVTIKHVAADAGVSLQTVSRVINDEPNVRSAMKARVQASIDKLGYVPSIAARRMSGSRSYLILAINDRDRTIAD
WTARQGTDWVDQMLLGGMLKCAEYGYRLIFELVDTHSDHVERELRATIAALQPDGVILTPPHSDNPLIVRLLERQRIPFA
RIGSRGGGAGIALVMDDESMARHATRHLIDLGHRRIAFIAGSSEYPLSQWRVDGWESEMRAAGLPTAGLVARGDFTYESG
AAATRQLLGHPDRPSAIIASNDQMALAALEVARELGIEIPSQLSLVSFDNTPIVRFTQPTLTAVDQPVAETVSRAVEMII
KAQRGEKLPPQPVIVAGGFVERESTSAPAHG
>Mature_350_residues
ARRRQAVTIKHVAADAGVSLQTVSRVINDEPNVRSAMKARVQASIDKLGYVPSIAARRMSGSRSYLILAINDRDRTIADW
TARQGTDWVDQMLLGGMLKCAEYGYRLIFELVDTHSDHVERELRATIAALQPDGVILTPPHSDNPLIVRLLERQRIPFAR
IGSRGGGAGIALVMDDESMARHATRHLIDLGHRRIAFIAGSSEYPLSQWRVDGWESEMRAAGLPTAGLVARGDFTYESGA
AATRQLLGHPDRPSAIIASNDQMALAALEVARELGIEIPSQLSLVSFDNTPIVRFTQPTLTAVDQPVAETVSRAVEMIIK
AQRGEKLPPQPVIVAGGFVERESTSAPAHG

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=328, Percent_Identity=29.5731707317073, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790194, Length=314, Percent_Identity=29.2993630573248, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789068, Length=345, Percent_Identity=29.2753623188406, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787948, Length=343, Percent_Identity=29.1545189504373, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788474, Length=350, Percent_Identity=28.8571428571429, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786540, Length=348, Percent_Identity=26.1494252873563, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789202, Length=354, Percent_Identity=28.2485875706215, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=26.2048192771084, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=25.3776435045317, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789456, Length=328, Percent_Identity=27.4390243902439, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790689, Length=344, Percent_Identity=27.3255813953488, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787906, Length=307, Percent_Identity=28.9902280130293, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=21.875, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38232; Mature: 38101

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRRQAVTIKHVAADAGVSLQTVSRVINDEPNVRSAMKARVQASIDKLGYVPSIAARRM
CCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHC
SGSRSYLILAINDRDRTIADWTARQGTDWVDQMLLGGMLKCAEYGYRLIFELVDTHSDHV
CCCCCEEEEEECCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ERELRATIAALQPDGVILTPPHSDNPLIVRLLERQRIPFARIGSRGGGAGIALVMDDESM
HHHHHHHHHHCCCCCEEECCCCCCCCHHHEEHHHHCCCHHHCCCCCCCCEEEEEECCHHH
ARHATRHLIDLGHRRIAFIAGSSEYPLSQWRVDGWESEMRAAGLPTAGLVARGDFTYESG
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCHHHHHHCCCCCCCEEECCCCCCCCC
AAATRQLLGHPDRPSAIIASNDQMALAALEVARELGIEIPSQLSLVSFDNTPIVRFTQPT
HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCH
LTAVDQPVAETVSRAVEMIIKAQRGEKLPPQPVIVAGGFVERESTSAPAHG
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEECCCCCCCCCC
>Mature Secondary Structure 
ARRRQAVTIKHVAADAGVSLQTVSRVINDEPNVRSAMKARVQASIDKLGYVPSIAARRM
CCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHC
SGSRSYLILAINDRDRTIADWTARQGTDWVDQMLLGGMLKCAEYGYRLIFELVDTHSDHV
CCCCCEEEEEECCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ERELRATIAALQPDGVILTPPHSDNPLIVRLLERQRIPFARIGSRGGGAGIALVMDDESM
HHHHHHHHHHCCCCCEEECCCCCCCCHHHEEHHHHCCCHHHCCCCCCCCEEEEEECCHHH
ARHATRHLIDLGHRRIAFIAGSSEYPLSQWRVDGWESEMRAAGLPTAGLVARGDFTYESG
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCHHHHHHCCCCCCCEEECCCCCCCCC
AAATRQLLGHPDRPSAIIASNDQMALAALEVARELGIEIPSQLSLVSFDNTPIVRFTQPT
HHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCH
LTAVDQPVAETVSRAVEMIIKAQRGEKLPPQPVIVAGGFVERESTSAPAHG
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]