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The map label for this gene is paaG [H]

Identifier: 103486342

GI number: 103486342

Start: 859857

End: 860654

Strand: Direct

Name: paaG [H]

Synonym: Sala_0852

Alternate gene names: 103486342

Gene position: 859857-860654 (Clockwise)

Preceding gene: 103486341

Following gene: 103486343

Centisome position: 25.7

GC content: 63.28

Gene sequence:

>798_bases
ATGTCCGAACTGCTGATCGAAGATGATGCGGGGGTCCGCATCATAACGCTCAACCGGCCCGACCGTTTGAATGCGCTTAC
CGGTTCGATCATGGCATCGCTTGCCGATGCCTGCGCCGACGCCGCGCGCGATGCGTCGGTGGGCTGTGTCGTCGTGACCG
GCGCGGGCCGTGGCTTTTGCGCGGGCGGCGACCTGAAGGAAGGCGGTGCCGACAAGGCCGTGGTGCCGCCGAACGCCGAG
GCAGGCAGCCGAACCGAACAGAGTTTCGCCCGGCTGCGCGGCTTTATGGAAACCTCGCGTCTCCTCCATGAAATGCCCAA
GCCGACCATCGCGATGGTCAATGGCCCGGTGGCCGGGGCTGGAATAGGCATCGCGGGGGCCTGCGATCTGCGCTTCGCGT
CGAAAAGCGCTACCTTTCTGACCGCTTTTGACCGGATCGGGGCGGGGGGCGATTTTGGTTCGACCTGGTTCTGGACCAAG
ATTCTGGGCACCGGGGTGGCGCGCGAGCTGTTCTTCCTTGGCGAAAAATTGTCGGCCGAGGAGGCGTTCGCCAAGGGCAT
TTATACGCGCTTGTTTGAAGAAGCGGACTTGCGCCCGGAAACGATGCAGGCCGCCCGCCGCCTCGCCGACGGGCCACGCA
TGGGCTATCGGTACATGAAGGCGAACCTCAACAATGCGGAAGATTGGGCCTTCGAAGCCGCGCTTGATGCCGAAGCATTG
AACATGGGGCTTTCGACCGGCGCAACCGCGTTGATCTGGCGCGAAAAGAAAAAGCGGGAAGAACAGGGCGGTGGCTGA

Upstream 100 bases:

>100_bases
CGAAAAGGCGGTCAAGATGCTCGCCCGGCACCGCGAACTCGGCGGGGATTGATCCGCTCCTCCATTCCTTCGAAAAGATC
GGAACAGAGAGGGGGCTGCC

Downstream 100 bases:

>100_bases
ACCCGACCATATTCGCATCGAACGCCGCGAGCATGGAATCGCAGCCGTTGTGGTGGATCGCGCCGACATCGGCAATGCCT
CCTCGCCCGAAATGCTGGGC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSELLIEDDAGVRIITLNRPDRLNALTGSIMASLADACADAARDASVGCVVVTGAGRGFCAGGDLKEGGADKAVVPPNAE
AGSRTEQSFARLRGFMETSRLLHEMPKPTIAMVNGPVAGAGIGIAGACDLRFASKSATFLTAFDRIGAGGDFGSTWFWTK
ILGTGVARELFFLGEKLSAEEAFAKGIYTRLFEEADLRPETMQAARRLADGPRMGYRYMKANLNNAEDWAFEAALDAEAL
NMGLSTGATALIWREKKKREEQGGG

Sequences:

>Translated_265_residues
MSELLIEDDAGVRIITLNRPDRLNALTGSIMASLADACADAARDASVGCVVVTGAGRGFCAGGDLKEGGADKAVVPPNAE
AGSRTEQSFARLRGFMETSRLLHEMPKPTIAMVNGPVAGAGIGIAGACDLRFASKSATFLTAFDRIGAGGDFGSTWFWTK
ILGTGVARELFFLGEKLSAEEAFAKGIYTRLFEEADLRPETMQAARRLADGPRMGYRYMKANLNNAEDWAFEAALDAEAL
NMGLSTGATALIWREKKKREEQGGG
>Mature_264_residues
SELLIEDDAGVRIITLNRPDRLNALTGSIMASLADACADAARDASVGCVVVTGAGRGFCAGGDLKEGGADKAVVPPNAEA
GSRTEQSFARLRGFMETSRLLHEMPKPTIAMVNGPVAGAGIGIAGACDLRFASKSATFLTAFDRIGAGGDFGSTWFWTKI
LGTGVARELFFLGEKLSAEEAFAKGIYTRLFEEADLRPETMQAARRLADGPRMGYRYMKANLNNAEDWAFEAALDAEALN
MGLSTGATALIWREKKKREEQGGG

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=239, Percent_Identity=28.8702928870293, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI260275230, Length=239, Percent_Identity=28.8702928870293, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI260274832, Length=239, Percent_Identity=28.8702928870293, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI70995211, Length=230, Percent_Identity=27.3913043478261, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI31542718, Length=260, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI194097323, Length=217, Percent_Identity=29.4930875576037, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI25453481, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI51538573, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI4757966, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI51538581, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4757968, Length=206, Percent_Identity=28.1553398058252, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=206, Percent_Identity=28.1553398058252, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221136756, Length=208, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI221136753, Length=208, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI221307494, Length=208, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI116235487, Length=188, Percent_Identity=28.7234042553192, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI37594469, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI37594471, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI213417737, Length=237, Percent_Identity=24.0506329113924, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI157694516, Length=237, Percent_Identity=24.0506329113924, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787660, Length=238, Percent_Identity=36.5546218487395, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=30.1587301587302, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787659, Length=239, Percent_Identity=31.3807531380753, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87082183, Length=215, Percent_Identity=26.046511627907, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI221142681, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=233, Percent_Identity=30.4721030042918, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=228, Percent_Identity=30.7017543859649, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17536985, Length=258, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=231, Percent_Identity=29.004329004329, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=234, Percent_Identity=30.3418803418803, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=210, Percent_Identity=26.1904761904762, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=24.609375, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=246, Percent_Identity=25.2032520325203, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=199, Percent_Identity=25.6281407035176, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144157, Length=199, Percent_Identity=25.6281407035176, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654903, Length=210, Percent_Identity=27.1428571428571, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI20129971, Length=229, Percent_Identity=27.5109170305677, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653477, Length=229, Percent_Identity=27.5109170305677, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=27.8225806451613, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920382, Length=186, Percent_Identity=28.494623655914, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653139, Length=234, Percent_Identity=28.6324786324786, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357171, Length=238, Percent_Identity=24.7899159663866, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28137; Mature: 28006

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELLIEDDAGVRIITLNRPDRLNALTGSIMASLADACADAARDASVGCVVVTGAGRGFC
CCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEE
AGGDLKEGGADKAVVPPNAEAGSRTEQSFARLRGFMETSRLLHEMPKPTIAMVNGPVAGA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GIGIAGACDLRFASKSATFLTAFDRIGAGGDFGSTWFWTKILGTGVARELFFLGEKLSAE
CCCCCCEECEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
EAFAKGIYTRLFEEADLRPETMQAARRLADGPRMGYRYMKANLNNAEDWAFEAALDAEAL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCHHHEECCCCCCHHHHHHHHHHHHHH
NMGLSTGATALIWREKKKREEQGGG
HCCCCCCCEEEEECHHHHHHHCCCC
>Mature Secondary Structure 
SELLIEDDAGVRIITLNRPDRLNALTGSIMASLADACADAARDASVGCVVVTGAGRGFC
CCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEE
AGGDLKEGGADKAVVPPNAEAGSRTEQSFARLRGFMETSRLLHEMPKPTIAMVNGPVAGA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GIGIAGACDLRFASKSATFLTAFDRIGAGGDFGSTWFWTKILGTGVARELFFLGEKLSAE
CCCCCCEECEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
EAFAKGIYTRLFEEADLRPETMQAARRLADGPRMGYRYMKANLNNAEDWAFEAALDAEAL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCHHHEECCCCCCHHHHHHHHHHHHHH
NMGLSTGATALIWREKKKREEQGGG
HCCCCCCCEEEEECHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]