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The map label for this gene is cdd [H]

Identifier: 103486255

GI number: 103486255

Start: 771263

End: 771718

Strand: Reverse

Name: cdd [H]

Synonym: Sala_0763

Alternate gene names: 103486255

Gene position: 771718-771263 (Counterclockwise)

Preceding gene: 103486256

Following gene: 103486254

Centisome position: 23.07

GC content: 66.89

Gene sequence:

>456_bases
ATGACCGACACGACGACCCGCAACGCGCTGATCGCCGCCGCGCGCGATGCCGCGAGCCGCGCCTACGCGCCCTATTCGGG
CTTTCATGTCGGCGCCGCGCTGCTGCTCAAAAATGGCGATGTCGTGACCGGCGCCAATGTCGAAAATGCGAGCTATGGGC
TGACGCTCTGCGCCGAAACCGCCGCGGTGGCGAAGATCGCGAACGAAGGCTGGATCGGTGAACTGGCCGAAGTCGCGATT
GTCGGCGGCCGTCCCGACGGCGAGGCGCTGACCGGCAGCGATCCCGTCCATCCCTGCGGGCGCTGCCGCCAGATATTGAA
CGAGGCCGCCGAACGATCGCAGACCGACATCCTGGTCCATTGCGCCTCGGGCGACGACAGCGCGGTCGCAACGTACAAGC
TCAGCGAGCTGCTTCCCGCAGCGTTCGGGCCGAAGGATCTGGGGCTGATCGACTGA

Upstream 100 bases:

>100_bases
CGCATCCCTGGACGATGTGGCAGGCGAATGATTATGTCCGCCTGTCGGGCGCCGACGGCACCGTCGGCTGGAACGTGCTG
CGCGCAGGTGGAGAGATGCG

Downstream 100 bases:

>100_bases
CCGCTTGCGCAACACCTCCCATCCCGACAAGAGACACGCATGGCCATTCTTTCCGATCGCTGGATTCGCGAAGCCGCCCG
GACGCAGGGCATGATCGAAC

Product: cytidine deaminase, homotetrameric

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTDTTTRNALIAAARDAASRAYAPYSGFHVGAALLLKNGDVVTGANVENASYGLTLCAETAAVAKIANEGWIGELAEVAI
VGGRPDGEALTGSDPVHPCGRCRQILNEAAERSQTDILVHCASGDDSAVATYKLSELLPAAFGPKDLGLID

Sequences:

>Translated_151_residues
MTDTTTRNALIAAARDAASRAYAPYSGFHVGAALLLKNGDVVTGANVENASYGLTLCAETAAVAKIANEGWIGELAEVAI
VGGRPDGEALTGSDPVHPCGRCRQILNEAAERSQTDILVHCASGDDSAVATYKLSELLPAAFGPKDLGLID
>Mature_150_residues
TDTTTRNALIAAARDAASRAYAPYSGFHVGAALLLKNGDVVTGANVENASYGLTLCAETAAVAKIANEGWIGELAEVAIV
GGRPDGEALTGSDPVHPCGRCRQILNEAAERSQTDILVHCASGDDSAVATYKLSELLPAAFGPKDLGLID

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=140, Percent_Identity=37.1428571428571, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17540514, Length=142, Percent_Identity=38.7323943661972, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551074, Length=144, Percent_Identity=36.1111111111111, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6323274, Length=139, Percent_Identity=38.8489208633094, Blast_Score=89, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920920, Length=130, Percent_Identity=40.7692307692308, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582741, Length=99, Percent_Identity=39.3939393939394, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582744, Length=146, Percent_Identity=35.6164383561644, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 15512; Mature: 15381

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTTTRNALIAAARDAASRAYAPYSGFHVGAALLLKNGDVVTGANVENASYGLTLCAET
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCEEECCCCCCCCCCEEEHHHH
AAVAKIANEGWIGELAEVAIVGGRPDGEALTGSDPVHPCGRCRQILNEAAERSQTDILVH
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
CASGDDSAVATYKLSELLPAAFGPKDLGLID
ECCCCCCEEEEEEHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TDTTTRNALIAAARDAASRAYAPYSGFHVGAALLLKNGDVVTGANVENASYGLTLCAET
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCEEECCCCCCCCCCEEEHHHH
AAVAKIANEGWIGELAEVAIVGGRPDGEALTGSDPVHPCGRCRQILNEAAERSQTDILVH
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
CASGDDSAVATYKLSELLPAAFGPKDLGLID
ECCCCCCEEEEEEHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]