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The map label for this gene is ilvY [H]

Identifier: 103486199

GI number: 103486199

Start: 711153

End: 712034

Strand: Direct

Name: ilvY [H]

Synonym: Sala_0706

Alternate gene names: 103486199

Gene position: 711153-712034 (Clockwise)

Preceding gene: 103486197

Following gene: 103486201

Centisome position: 21.26

GC content: 69.16

Gene sequence:

>882_bases
ATGTACGATTGGAACGATCTCAAGGCCTTTCTGGCCGTCGCCGAAACGGGCAGCACGCTCGCCGCCGCCCAGGCGATGCG
CGTCAGCCAGACGACCGTTGCGCGGCGTATCGCCGCGCTCGAAGCGGCCACCGGGGTCACGCTCTTCGAACGGCGGCAGG
CGGGCTATGCGCTCACCCCGGTGGGGGAGGCGATGCTGGCGAGCGCGGTGGCGGTCCGCGATGCCGCGGATCGCTTTGGC
GAGGCCGCGAGCGCGCGCTCGCGCGATGCGGGCGGAACGGTCAGCCTGACGGTCATGGAAATCATCGCGGTGACGATCCT
GCCGCCGATCCTGCGCGACCTGCGCGCCGAACATCCCGCCATCCATATCCAGCTCGACACGTCCGACGAAGCGCGCGACC
TCGCCGCCGGCGCCGCCGACATCGCGATCCGCAGCAGCAAGCAGCCGTCGGGCGCGGGCCTTGTCGGGCGGCGTATCGCC
GACAATGCGTGGACCGTCTATTGCAGCTGCGACTATGCCGACCGCCACGGTGTCCCGCACACGCGCGAGGAACTCGCGAA
GCATCCCTTCATCGGTGGCGGCGGCGGCGTCTGGGAGCCCTATCGCGCGTGGCTGCGCCAATATGGGCTCGAGGAATCGG
TGGTCATGCAATATGACACGGCGACCGGCCTGCTGTCGGGCGTGCGCGCGGGGATGGGACTGTCGGTGCTGCCCGCCTAT
CTTGCCGACCGCGAACCCGATCTCATCCGTTGTCTGCCGCCCAGGAGCGACGACACCACGGGGCTGTGGCTGCTCACCCA
CGAACGGCTGCGCCATGTCCCGCGCGTGCGGCTGGTGCTCGATTTCCTGGCGAGGGAATTGACCAGACTGGCGCGCGATT
AA

Upstream 100 bases:

>100_bases
TTATACCAGCCGCCGCCGCTGCCGCGGGAGCAACGATGTTGCGCGCCCATTCTGCAAAATTGCAGAATGGGCGCGCGGCG
ATTATGATGCACAAGGCGCC

Downstream 100 bases:

>100_bases
CTATTTCATCCGCGCACAGCCCAGCGCCGCCGCGTCGATCGCGGTCGCCGCGCCGCGCAGGCGATAGGTGTCGGCGATCG
CGCCGCCCGCCGCCGCGCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MYDWNDLKAFLAVAETGSTLAAAQAMRVSQTTVARRIAALEAATGVTLFERRQAGYALTPVGEAMLASAVAVRDAADRFG
EAASARSRDAGGTVSLTVMEIIAVTILPPILRDLRAEHPAIHIQLDTSDEARDLAAGAADIAIRSSKQPSGAGLVGRRIA
DNAWTVYCSCDYADRHGVPHTREELAKHPFIGGGGGVWEPYRAWLRQYGLEESVVMQYDTATGLLSGVRAGMGLSVLPAY
LADREPDLIRCLPPRSDDTTGLWLLTHERLRHVPRVRLVLDFLARELTRLARD

Sequences:

>Translated_293_residues
MYDWNDLKAFLAVAETGSTLAAAQAMRVSQTTVARRIAALEAATGVTLFERRQAGYALTPVGEAMLASAVAVRDAADRFG
EAASARSRDAGGTVSLTVMEIIAVTILPPILRDLRAEHPAIHIQLDTSDEARDLAAGAADIAIRSSKQPSGAGLVGRRIA
DNAWTVYCSCDYADRHGVPHTREELAKHPFIGGGGGVWEPYRAWLRQYGLEESVVMQYDTATGLLSGVRAGMGLSVLPAY
LADREPDLIRCLPPRSDDTTGLWLLTHERLRHVPRVRLVLDFLARELTRLARD
>Mature_293_residues
MYDWNDLKAFLAVAETGSTLAAAQAMRVSQTTVARRIAALEAATGVTLFERRQAGYALTPVGEAMLASAVAVRDAADRFG
EAASARSRDAGGTVSLTVMEIIAVTILPPILRDLRAEHPAIHIQLDTSDEARDLAAGAADIAIRSSKQPSGAGLVGRRIA
DNAWTVYCSCDYADRHGVPHTREELAKHPFIGGGGGVWEPYRAWLRQYGLEESVVMQYDTATGLLSGVRAGMGLSVLPAY
LADREPDLIRCLPPRSDDTTGLWLLTHERLRHVPRVRLVLDFLARELTRLARD

Specific function: This protein activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790208, Length=276, Percent_Identity=28.9855072463768, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787879, Length=277, Percent_Identity=27.0758122743682, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789173, Length=272, Percent_Identity=24.6323529411765, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787589, Length=280, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786401, Length=249, Percent_Identity=24.4979919678715, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788706, Length=177, Percent_Identity=27.1186440677966, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31785; Mature: 31785

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDWNDLKAFLAVAETGSTLAAAQAMRVSQTTVARRIAALEAATGVTLFERRQAGYALTP
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEECC
VGEAMLASAVAVRDAADRFGEAASARSRDAGGTVSLTVMEIIAVTILPPILRDLRAEHPA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCE
IHIQLDTSDEARDLAAGAADIAIRSSKQPSGAGLVGRRIADNAWTVYCSCDYADRHGVPH
EEEEECCCCHHHHHHCCHHHHEEECCCCCCCCCHHHHEECCCCEEEEEEECCHHCCCCCC
TREELAKHPFIGGGGGVWEPYRAWLRQYGLEESVVMQYDTATGLLSGVRAGMGLSVLPAY
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCHHHHHHH
LADREPDLIRCLPPRSDDTTGLWLLTHERLRHVPRVRLVLDFLARELTRLARD
HCCCCCCEEEECCCCCCCCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYDWNDLKAFLAVAETGSTLAAAQAMRVSQTTVARRIAALEAATGVTLFERRQAGYALTP
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEECC
VGEAMLASAVAVRDAADRFGEAASARSRDAGGTVSLTVMEIIAVTILPPILRDLRAEHPA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCE
IHIQLDTSDEARDLAAGAADIAIRSSKQPSGAGLVGRRIADNAWTVYCSCDYADRHGVPH
EEEEECCCCHHHHHHCCHHHHEEECCCCCCCCCHHHHEECCCCEEEEEEECCHHCCCCCC
TREELAKHPFIGGGGGVWEPYRAWLRQYGLEESVVMQYDTATGLLSGVRAGMGLSVLPAY
HHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCHHHHHHH
LADREPDLIRCLPPRSDDTTGLWLLTHERLRHVPRVRLVLDFLARELTRLARD
HCCCCCCEEEECCCCCCCCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3003115; 1379743; 9278503; 3550695 [H]