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The map label for this gene is crt [H]

Identifier: 103486076

GI number: 103486076

Start: 593134

End: 594057

Strand: Reverse

Name: crt [H]

Synonym: Sala_0583

Alternate gene names: 103486076

Gene position: 594057-593134 (Counterclockwise)

Preceding gene: 103486080

Following gene: 103486074

Centisome position: 17.76

GC content: 68.72

Gene sequence:

>924_bases
ATGAGCTTCGACCAGATTCGCCTCGACCGCCACGAGGGCATCGCGCTGCTGACCTTGCACCGCCCCGACCGGATGAACGC
CTTTACCACCCAAATGATGCTGGAGATCGTCGCCGCGCTCGACGAATGCGACGCCGACGACGGGGTGCGCGCGGTGATCT
TCACCGGGTCGGGCGAAAAGGCCTATTGCGCCGGCGCCGATCTGGGCCAGGGCGCGGCGACCTTCGATTATGACAAGCGA
ACCGACAAGGCGGCGATCCTGCCCGACGGCTTCCCCGCCAGCCCGGTGGCCGAAGACGGCACGATCGACTGGTCGCACCC
GCTGATCCGCGATTCGGGCGGGCGCGTGTCGATGCGCATCTTCGACGCCAAAAAGCCCGTGCTTGGCGCGATCAACGGCG
CCGCGGTCGGCATCGGGGCGACGATGACCCTGTCGATGGACGCGCGCCTCGCGAGCGACACCGCGCGTTACGGCTTTGTC
TTTGCGCGGCGCGGCATCGTCCCCGAAGCGGCGTCGAGCTGGTTCCTGCCCCGCCTCGTCGGCATCCAGACTGCGGTCGA
CTGGTGCTTTTCGGGGCGGCTGATCCCGGCAGCGGAAGCGCGTGAAAAGGGCCTTGTCCAGTCGATCCACGCCCCCGGCG
AGCTGGTCGACGCCGCGATCGCCAGGGCGCGCGAGCTGACCGAGCATAGCGCCCCGGTGTCGGTCGCGCTGACGCGCCAC
ATGCTCTGGCGGATGCTTGGCGCGCCGCATCCGATGAGCGCGCACCGCTGGGACAGCCGCGCGATCTTTGCCCGCGGCCG
CAGCCCCGACGCCGCCGAGGGGGTGTCGAGCTTCCTCGAAAAGCGTCCCGCCAATTTCACGGCGAGCGTTGCGAACGACT
ATCCCTGGTTCGCCGAGTTCGAAGAGGCGCCGCCCTATAGCTAG

Upstream 100 bases:

>100_bases
GGGCGAAGGTTGGGGAGCGATCACGCCTTACGTTTACGTAAAGTGCTTGCGTTCAGCGGCCGAGCTTGCAACCCTGCCGG
CGACCGAAGGAGAGAGATGG

Downstream 100 bases:

>100_bases
GATCAGGACATCCGTTTGCCGCGCGGCGCCGGGAAGCCCGGCGCCGCGAGTCCTGCCGTCCCAAACCGGATCAGCGGGCG
CCGGTCGATCGCTCTCCAGG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSFDQIRLDRHEGIALLTLHRPDRMNAFTTQMMLEIVAALDECDADDGVRAVIFTGSGEKAYCAGADLGQGAATFDYDKR
TDKAAILPDGFPASPVAEDGTIDWSHPLIRDSGGRVSMRIFDAKKPVLGAINGAAVGIGATMTLSMDARLASDTARYGFV
FARRGIVPEAASSWFLPRLVGIQTAVDWCFSGRLIPAAEAREKGLVQSIHAPGELVDAAIARARELTEHSAPVSVALTRH
MLWRMLGAPHPMSAHRWDSRAIFARGRSPDAAEGVSSFLEKRPANFTASVANDYPWFAEFEEAPPYS

Sequences:

>Translated_307_residues
MSFDQIRLDRHEGIALLTLHRPDRMNAFTTQMMLEIVAALDECDADDGVRAVIFTGSGEKAYCAGADLGQGAATFDYDKR
TDKAAILPDGFPASPVAEDGTIDWSHPLIRDSGGRVSMRIFDAKKPVLGAINGAAVGIGATMTLSMDARLASDTARYGFV
FARRGIVPEAASSWFLPRLVGIQTAVDWCFSGRLIPAAEAREKGLVQSIHAPGELVDAAIARARELTEHSAPVSVALTRH
MLWRMLGAPHPMSAHRWDSRAIFARGRSPDAAEGVSSFLEKRPANFTASVANDYPWFAEFEEAPPYS
>Mature_306_residues
SFDQIRLDRHEGIALLTLHRPDRMNAFTTQMMLEIVAALDECDADDGVRAVIFTGSGEKAYCAGADLGQGAATFDYDKRT
DKAAILPDGFPASPVAEDGTIDWSHPLIRDSGGRVSMRIFDAKKPVLGAINGAAVGIGATMTLSMDARLASDTARYGFVF
ARRGIVPEAASSWFLPRLVGIQTAVDWCFSGRLIPAAEAREKGLVQSIHAPGELVDAAIARARELTEHSAPVSVALTRHM
LWRMLGAPHPMSAHRWDSRAIFARGRSPDAAEGVSSFLEKRPANFTASVANDYPWFAEFEEAPPYS

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=280, Percent_Identity=26.7857142857143, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI260274832, Length=207, Percent_Identity=29.951690821256, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI45643119, Length=207, Percent_Identity=29.951690821256, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI260275230, Length=207, Percent_Identity=29.951690821256, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI116235487, Length=249, Percent_Identity=27.710843373494, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4502327, Length=289, Percent_Identity=24.9134948096886, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787660, Length=286, Percent_Identity=29.3706293706294, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787659, Length=285, Percent_Identity=27.0175438596491, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI221142681, Length=283, Percent_Identity=27.5618374558304, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788597, Length=291, Percent_Identity=23.7113402061856, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788682, Length=253, Percent_Identity=23.7154150197628, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082183, Length=293, Percent_Identity=22.8668941979522, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790281, Length=223, Percent_Identity=25.5605381165919, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=276, Percent_Identity=26.4492753623188, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17549921, Length=210, Percent_Identity=32.8571428571429, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=281, Percent_Identity=28.1138790035587, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=285, Percent_Identity=25.2631578947368, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25144160, Length=231, Percent_Identity=23.3766233766234, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144157, Length=231, Percent_Identity=23.3766233766234, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=279, Percent_Identity=25.4480286738351, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653477, Length=279, Percent_Identity=25.4480286738351, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653139, Length=281, Percent_Identity=26.3345195729537, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357171, Length=222, Percent_Identity=26.5765765765766, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 33248; Mature: 33117

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDQIRLDRHEGIALLTLHRPDRMNAFTTQMMLEIVAALDECDADDGVRAVIFTGSGEK
CCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
AYCAGADLGQGAATFDYDKRTDKAAILPDGFPASPVAEDGTIDWSHPLIRDSGGRVSMRI
EEEECCCCCCCCEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEE
FDAKKPVLGAINGAAVGIGATMTLSMDARLASDTARYGFVFARRGIVPEAASSWFLPRLV
ECCCCCHHCCCCCCEEECCEEEEEEECCHHHHCHHHHHEEEECCCCCCHHHHHHHHHHHH
GIQTAVDWCFSGRLIPAAEAREKGLVQSIHAPGELVDAAIARARELTEHSAPVSVALTRH
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MLWRMLGAPHPMSAHRWDSRAIFARGRSPDAAEGVSSFLEKRPANFTASVANDYPWFAEF
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
EEAPPYS
CCCCCCC
>Mature Secondary Structure 
SFDQIRLDRHEGIALLTLHRPDRMNAFTTQMMLEIVAALDECDADDGVRAVIFTGSGEK
CCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
AYCAGADLGQGAATFDYDKRTDKAAILPDGFPASPVAEDGTIDWSHPLIRDSGGRVSMRI
EEEECCCCCCCCEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEE
FDAKKPVLGAINGAAVGIGATMTLSMDARLASDTARYGFVFARRGIVPEAASSWFLPRLV
ECCCCCHHCCCCCCEEECCEEEEEEECCHHHHCHHHHHEEEECCCCCCHHHHHHHHHHHH
GIQTAVDWCFSGRLIPAAEAREKGLVQSIHAPGELVDAAIARARELTEHSAPVSVALTRH
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MLWRMLGAPHPMSAHRWDSRAIFARGRSPDAAEGVSSFLEKRPANFTASVANDYPWFAEF
HHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
EEAPPYS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]