Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 103485830

GI number: 103485830

Start: 339509

End: 340108

Strand: Reverse

Name: ruvA

Synonym: Sala_0335

Alternate gene names: 103485830

Gene position: 340108-339509 (Counterclockwise)

Preceding gene: 103485831

Following gene: 103485829

Centisome position: 10.17

GC content: 70.17

Gene sequence:

>600_bases
ATGATCGCGAAACTCACCGGACGGCTCGACAGCAACGGCGCAGGCCATGCGGTGATCGATGTCGGCGGCGTCGGCTATCT
GGTCGAGGCGTCGGCGCGCACCCTCGACGCGCTGGGCGCGGTCGGCGGCGAGGTCACCATCCACACCGAAATGCTGGTGG
GTGAGGATTTTCTGCGCCTGCTCGGCTTCGCACGCGCCGAGGAACGCGACTGGTTCCGCCTGCTCACCAGCGTCCAGGGC
GTCGGCGCCAAGGTCGCGCTGGCGATCCTCTCGGCGCTCGAAGTCGCCGACCTGCAACGCGCGCTGGCGAGCGGCGACAG
CGCGATGATCGCGCGCGCCAACGGCGTCGGCCCGAAACTCGCGCAGCGCATCACGCATGAACTGAAGGACAAGGCCGGCG
CGCTCGGCGGCATTTCGGGGAGCGGCCCGGCCCTCTCGGCCGCCGCCGGCCCGGTCGGCGACGCCATTGCCGCACTCACC
GGCCTCGGCTTCAAACCCGGCGAAGCCAGCGCCGCGGTCGCGGCGGCTAATGAGGAATTGGGCGCGGATGCCAGCCTTGA
TGCACTTGTCCGCGTGGCGCTCAAGAAAGCGGCGAAGTGA

Upstream 100 bases:

>100_bases
CATTCGCCTCTCAGATCAAATCAAGCCGACGAACGTACAACGCCTTTGACAAAGCCGGAAACCGATTCCCTTTTCGTTCT
CCTCGCGCTACGCAGTTTCC

Downstream 100 bases:

>100_bases
CCGACCGCACCCGCCACCCATCCTGCCGCTGCGGGCAGGTGCGCATCGCCTGCACCGGCGAGCCGATCCGCGTGTCGGTG
TGCCATTGCCGCGAGTGCAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIAKLTGRLDSNGAGHAVIDVGGVGYLVEASARTLDALGAVGGEVTIHTEMLVGEDFLRLLGFARAEERDWFRLLTSVQG
VGAKVALAILSALEVADLQRALASGDSAMIARANGVGPKLAQRITHELKDKAGALGGISGSGPALSAAAGPVGDAIAALT
GLGFKPGEASAAVAAANEELGADASLDALVRVALKKAAK

Sequences:

>Translated_199_residues
MIAKLTGRLDSNGAGHAVIDVGGVGYLVEASARTLDALGAVGGEVTIHTEMLVGEDFLRLLGFARAEERDWFRLLTSVQG
VGAKVALAILSALEVADLQRALASGDSAMIARANGVGPKLAQRITHELKDKAGALGGISGSGPALSAAAGPVGDAIAALT
GLGFKPGEASAAVAAANEELGADASLDALVRVALKKAAK
>Mature_199_residues
MIAKLTGRLDSNGAGHAVIDVGGVGYLVEASARTLDALGAVGGEVTIHTEMLVGEDFLRLLGFARAEERDWFRLLTSVQG
VGAKVALAILSALEVADLQRALASGDSAMIARANGVGPKLAQRITHELKDKAGALGGISGSGPALSAAAGPVGDAIAALT
GLGFKPGEASAAVAAANEELGADASLDALVRVALKKAAK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=34.6341463414634, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_SPHAL (Q1GWB4)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615391.1
- ProteinModelPortal:   Q1GWB4
- SMR:   Q1GWB4
- GeneID:   4081033
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0335
- NMPDR:   fig|317655.9.peg.310
- HOGENOM:   HBG635309
- OMA:   YKTAMSI
- ProtClustDB:   PRK00116
- BioCyc:   SALA317655:SALA_0335-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 19832; Mature: 19832

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAKLTGRLDSNGAGHAVIDVGGVGYLVEASARTLDALGAVGGEVTIHTEMLVGEDFLRL
CCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
LGFARAEERDWFRLLTSVQGVGAKVALAILSALEVADLQRALASGDSAMIARANGVGPKL
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
AQRITHELKDKAGALGGISGSGPALSAAAGPVGDAIAALTGLGFKPGEASAAVAAANEEL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCHHC
GADASLDALVRVALKKAAK
CCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAKLTGRLDSNGAGHAVIDVGGVGYLVEASARTLDALGAVGGEVTIHTEMLVGEDFLRL
CCCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
LGFARAEERDWFRLLTSVQGVGAKVALAILSALEVADLQRALASGDSAMIARANGVGPKL
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
AQRITHELKDKAGALGGISGSGPALSAAAGPVGDAIAALTGLGFKPGEASAAVAAANEEL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCHHC
GADASLDALVRVALKKAAK
CCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA