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The map label for this gene is pkn1 [H]

Identifier: 103485795

GI number: 103485795

Start: 299483

End: 300412

Strand: Reverse

Name: pkn1 [H]

Synonym: Sala_0300

Alternate gene names: 103485795

Gene position: 300412-299483 (Counterclockwise)

Preceding gene: 103485796

Following gene: 103485791

Centisome position: 8.98

GC content: 69.68

Gene sequence:

>930_bases
ATGATCCGCAGCGCCGCCTTGCCCGCGCTGCTTCTGATTGGCGCACTCGCAGCGTGCGGCGATGATCCCGACACTCCGCT
GGCCGAAACCAAGCCCCCCGAATGCCCCGCGATGCCGGCACAGGATTATGCCTGGATCCCCGGCGCGACCTTCACCCTCG
GTGCCGACGCGCAGCTGCCCGAAGAGGGGCCGCCGCGCGAAGTCACGGTCGCGGGCTTCTGGATCGCGACGCACGAGGTC
ACCAACGCCGAGTTCGCCGAATTCGTCCGCGCGACGGGCTATAAAACGCTCGCCGAGCAAGACCCGCCGCCGCTGCCCGG
CGCGCCGCCCGACATGCTTATCCCCGGTTCGGCGGTGTTCACCGCGCCGACCGACGGCAATCCGAACTGGTGGCGCTGGG
TCGTCGGCGCCGAGTGGCGTCACCCCGCCGGACCCGCGACGAACATCGACGGGCGCGGCCGCGACCCGGTGGTGCAGATC
GGCTATGAGGACGCGCTCGCCTTCGCCAAATGGAAGGGCAAGACGCTGCCGAGCGAGGAGCAATGGGAACTCGCCGCGGC
GAGCGGCGGCGCCGACCGCAACGTCCCCGTCGGCAAAGACGGCAAACCGCGCGCCAATTTTTATCAGGGCAGCTTTCCGC
TGCGCGACCTTGGCACCGATGGCTTCACCGGCCGCGCGCCGGTCGCCTGTTTTCCCGCCGACGCGCACGGCGTCCACGAC
CTCATCGGCAATGTCTGGGAATGGACGACGAGCGCGGCAGGCAGCGAGCGCAATGTCATCAAGGGCGGCAGCTTCCTGTG
CGCCGCCAATTATTGCGCCCGCTATCGCCCCGCCGCGCGCCAGTTCCAGGAACGCAGCCTGGGAACCGACCATATCGGCT
TCCGCCTGATCGACCCGGCGCGCCCGGCGCCGGACAAACCCACGCCGTAG

Upstream 100 bases:

>100_bases
CCTGGCGCACGCTGCGCCACGACCAGGGGCTGTCGGCCGAGGAAGCGGGCGAGGTGCTGGGGCAAATGGTGGCGGCGCTG
CTGGCGACGGTGGCCGACGA

Downstream 100 bases:

>100_bases
CGACGACGGGAACGGCGGCTTGCGACCGAAAGCAGCCGTTGGCATTTCGGGCTCTCTCCCCTTCAGGGGAGAGACACGAA
GGCTTGGCAGCTTGCTGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIRSAALPALLLIGALAACGDDPDTPLAETKPPECPAMPAQDYAWIPGATFTLGADAQLPEEGPPREVTVAGFWIATHEV
TNAEFAEFVRATGYKTLAEQDPPPLPGAPPDMLIPGSAVFTAPTDGNPNWWRWVVGAEWRHPAGPATNIDGRGRDPVVQI
GYEDALAFAKWKGKTLPSEEQWELAAASGGADRNVPVGKDGKPRANFYQGSFPLRDLGTDGFTGRAPVACFPADAHGVHD
LIGNVWEWTTSAAGSERNVIKGGSFLCAANYCARYRPAARQFQERSLGTDHIGFRLIDPARPAPDKPTP

Sequences:

>Translated_309_residues
MIRSAALPALLLIGALAACGDDPDTPLAETKPPECPAMPAQDYAWIPGATFTLGADAQLPEEGPPREVTVAGFWIATHEV
TNAEFAEFVRATGYKTLAEQDPPPLPGAPPDMLIPGSAVFTAPTDGNPNWWRWVVGAEWRHPAGPATNIDGRGRDPVVQI
GYEDALAFAKWKGKTLPSEEQWELAAASGGADRNVPVGKDGKPRANFYQGSFPLRDLGTDGFTGRAPVACFPADAHGVHD
LIGNVWEWTTSAAGSERNVIKGGSFLCAANYCARYRPAARQFQERSLGTDHIGFRLIDPARPAPDKPTP
>Mature_309_residues
MIRSAALPALLLIGALAACGDDPDTPLAETKPPECPAMPAQDYAWIPGATFTLGADAQLPEEGPPREVTVAGFWIATHEV
TNAEFAEFVRATGYKTLAEQDPPPLPGAPPDMLIPGSAVFTAPTDGNPNWWRWVVGAEWRHPAGPATNIDGRGRDPVVQI
GYEDALAFAKWKGKTLPSEEQWELAAASGGADRNVPVGKDGKPRANFYQGSFPLRDLGTDGFTGRAPVACFPADAHGVHD
LIGNVWEWTTSAAGSERNVIKGGSFLCAANYCARYRPAARQFQERSLGTDHIGFRLIDPARPAPDKPTP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=288, Percent_Identity=37.1527777777778, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI257470975, Length=284, Percent_Identity=35.2112676056338, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI257470977, Length=271, Percent_Identity=36.90036900369, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI194248088, Length=279, Percent_Identity=37.2759856630824, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI194248087, Length=274, Percent_Identity=36.1313868613139, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI226437577, Length=181, Percent_Identity=41.9889502762431, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI194248090, Length=204, Percent_Identity=37.2549019607843, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI20130397, Length=277, Percent_Identity=37.9061371841155, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33018; Mature: 33018

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSAALPALLLIGALAACGDDPDTPLAETKPPECPAMPAQDYAWIPGATFTLGADAQLP
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCC
EEGPPREVTVAGFWIATHEVTNAEFAEFVRATGYKTLAEQDPPPLPGAPPDMLIPGSAVF
CCCCCCEEEEEEEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCEEECCCEEE
TAPTDGNPNWWRWVVGAEWRHPAGPATNIDGRGRDPVVQIGYEDALAFAKWKGKTLPSEE
ECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCHH
QWELAAASGGADRNVPVGKDGKPRANFYQGSFPLRDLGTDGFTGRAPVACFPADAHGVHD
CEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCCCCCCCCCCEEEECCCCCHHHH
LIGNVWEWTTSAAGSERNVIKGGSFLCAANYCARYRPAARQFQERSLGTDHIGFRLIDPA
HHHHHHHHHHCCCCCCCCEECCCCEEEECHHHHHCCHHHHHHHHHCCCCCCCCEEEECCC
RPAPDKPTP
CCCCCCCCC
>Mature Secondary Structure
MIRSAALPALLLIGALAACGDDPDTPLAETKPPECPAMPAQDYAWIPGATFTLGADAQLP
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCC
EEGPPREVTVAGFWIATHEVTNAEFAEFVRATGYKTLAEQDPPPLPGAPPDMLIPGSAVF
CCCCCCEEEEEEEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCEEECCCEEE
TAPTDGNPNWWRWVVGAEWRHPAGPATNIDGRGRDPVVQIGYEDALAFAKWKGKTLPSEE
ECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCHH
QWELAAASGGADRNVPVGKDGKPRANFYQGSFPLRDLGTDGFTGRAPVACFPADAHGVHD
CEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCCCCCCCCCCEEEECCCCCHHHH
LIGNVWEWTTSAAGSERNVIKGGSFLCAANYCARYRPAARQFQERSLGTDHIGFRLIDPA
HHHHHHHHHHCCCCCCCCEECCCCEEEECHHHHHCCHHHHHHHHHCCCCCCCCEEEECCC
RPAPDKPTP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]