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The map label for this gene is glpD [H]

Identifier: 103485685

GI number: 103485685

Start: 198870

End: 200369

Strand: Reverse

Name: glpD [H]

Synonym: Sala_0189

Alternate gene names: 103485685

Gene position: 200369-198870 (Counterclockwise)

Preceding gene: 103485696

Following gene: 103485684

Centisome position: 5.99

GC content: 68.4

Gene sequence:

>1500_bases
ATGGCCGACACTCCCCCACCCTATGACATCATCGTCGTCGGCGGCGGGGTGAATGGCGCGGGCGTCGCGCGCGATGCCGC
GGGGCGCGGCGCGCGGGTGCTGCTGCTGGAGGCGGGCGACCTTGCGCAAGGCACCTCGTCGAAATCGACCAAGCTGATCC
ACGGCGGGCTGCGCTATCTTGAGCATTATGAGTTCACCCTCGTTCGCGAGGCGCTGAAGGAACGCGAGGTCTTGTGGAGC
ATCGCGCCGCACATCATCCGTCCGATGCGCTTTGTCCTGCCCTATCGCGACGGGCTGCGCCCGCGCTGGTTGCTGCGGCT
GGGGCTGTTCCTCTATGACCATATCGGCGGGCGCAGGAAGCTGCCCGGGACGCGCTCGATCGACCTCAGGCGCCATGTAG
CGGGCGCGCCGCTGCAATCGCATTATGTCCATGGCTTTGAATATTCGGACGGCTGGGTCGACGACGCGCGGCTGGTGCTG
CTCAACGCGCGCGATGCCGCCGATCGCGGCGCGCGCGTCCGCACGCGCACGCGCGCCGAGATGCTGCGCTGCGACGGCGG
GCTGTGGGTCGTCGACGCGGCGGACGATCAGGGGCATCGCTATCGCTTCACCGGCCGCAGCGTGGTCAATGCCGCGGGGC
CGGCGGTGCTCGACCTGTTGAAACGCGCCGATGCGGAGCCCGACCATCAGATGCGCCTCGTGCGCGGATCGCACATCGTC
GTGCGCCGCCTGTTCGAGCATCATTATTCCTATTTTTTCCAGCTGCCTGACGGGCGCATCTTCTTTGCCATTCCCTATGA
GCACGACTTCACGCTGATCGGCACCACCGACGTGGACCATGACGGACCCGCGAGCGAGGCGCAGGCGAGCGAGGCGGAAA
TCGCCTATCTGTGCGAGGGCGCGAGCCTCTATTTCCGCACCCCCGTCACCCCGGCCGACGTGGTGTGGACCTATTCGGGC
GTGCGGCCGCTGGTCGAAGACGGATCGGGGCGGCCCGAGGCGGCGACGCGCGGATACCGGATCGACCTCGACATGGAAGA
AGGCGCGCCGCTGCTCACCATCTATGGCGGCAAAATCACCAGCTATCGCCATGTCGCCGAGGAGGCGGTCGACGCGCTCG
CGCGCCATGTGCCGGCGCTGACGGGCAAGCACTGGACGGCGAAGGCGGCGCTGCCCGGCGGCGATTTTCCGATGACCGGC
GCCGCGGCGCTGGCCGCCGAATATCGATCCGCTCACCCCTTTCTCGCGGCGACGACCGCCGAGCGGATCGCGCGCGCCTA
TGGCACCGGGGCGCGGCGCTGGCTGGGCGATGCGGGCGACTGGGACGCGCTGGGCGGCGAGATCGCGCACGGCCTGAGCG
TCGCCGAGGTCGAGTGGATGGTCGAACAGGAATGGGCGCGCACGGCCGACGATATTTTGTGGCGGCGGAGCAAGCTGGGA
CTCGTCTTCGGCGAGGAAGACAAGGCGCGGTTTGCAGCGACGCTGCGCGAACTGCAATAG

Upstream 100 bases:

>100_bases
TTCCGAAGGCTGGAGATTGGCTGGCCTCCGGCCGCCTTCGGCCCGCTCCGCTCGCAAAGACGATTCCATTCGATGCCGTC
CGGCTTTAAGAAGCCACGCC

Downstream 100 bases:

>100_bases
GTCTTTCCGCTCGATGCCGCACTGTCGCGGCGGATCGGTTAGGAAGCGGTGATGAACGACGCGGCGATCGACCTTCCTGT
CCGGCGGTTGGGGCTCGGCG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MADTPPPYDIIVVGGGVNGAGVARDAAGRGARVLLLEAGDLAQGTSSKSTKLIHGGLRYLEHYEFTLVREALKEREVLWS
IAPHIIRPMRFVLPYRDGLRPRWLLRLGLFLYDHIGGRRKLPGTRSIDLRRHVAGAPLQSHYVHGFEYSDGWVDDARLVL
LNARDAADRGARVRTRTRAEMLRCDGGLWVVDAADDQGHRYRFTGRSVVNAAGPAVLDLLKRADAEPDHQMRLVRGSHIV
VRRLFEHHYSYFFQLPDGRIFFAIPYEHDFTLIGTTDVDHDGPASEAQASEAEIAYLCEGASLYFRTPVTPADVVWTYSG
VRPLVEDGSGRPEAATRGYRIDLDMEEGAPLLTIYGGKITSYRHVAEEAVDALARHVPALTGKHWTAKAALPGGDFPMTG
AAALAAEYRSAHPFLAATTAERIARAYGTGARRWLGDAGDWDALGGEIAHGLSVAEVEWMVEQEWARTADDILWRRSKLG
LVFGEEDKARFAATLRELQ

Sequences:

>Translated_499_residues
MADTPPPYDIIVVGGGVNGAGVARDAAGRGARVLLLEAGDLAQGTSSKSTKLIHGGLRYLEHYEFTLVREALKEREVLWS
IAPHIIRPMRFVLPYRDGLRPRWLLRLGLFLYDHIGGRRKLPGTRSIDLRRHVAGAPLQSHYVHGFEYSDGWVDDARLVL
LNARDAADRGARVRTRTRAEMLRCDGGLWVVDAADDQGHRYRFTGRSVVNAAGPAVLDLLKRADAEPDHQMRLVRGSHIV
VRRLFEHHYSYFFQLPDGRIFFAIPYEHDFTLIGTTDVDHDGPASEAQASEAEIAYLCEGASLYFRTPVTPADVVWTYSG
VRPLVEDGSGRPEAATRGYRIDLDMEEGAPLLTIYGGKITSYRHVAEEAVDALARHVPALTGKHWTAKAALPGGDFPMTG
AAALAAEYRSAHPFLAATTAERIARAYGTGARRWLGDAGDWDALGGEIAHGLSVAEVEWMVEQEWARTADDILWRRSKLG
LVFGEEDKARFAATLRELQ
>Mature_498_residues
ADTPPPYDIIVVGGGVNGAGVARDAAGRGARVLLLEAGDLAQGTSSKSTKLIHGGLRYLEHYEFTLVREALKEREVLWSI
APHIIRPMRFVLPYRDGLRPRWLLRLGLFLYDHIGGRRKLPGTRSIDLRRHVAGAPLQSHYVHGFEYSDGWVDDARLVLL
NARDAADRGARVRTRTRAEMLRCDGGLWVVDAADDQGHRYRFTGRSVVNAAGPAVLDLLKRADAEPDHQMRLVRGSHIVV
RRLFEHHYSYFFQLPDGRIFFAIPYEHDFTLIGTTDVDHDGPASEAQASEAEIAYLCEGASLYFRTPVTPADVVWTYSGV
RPLVEDGSGRPEAATRGYRIDLDMEEGAPLLTIYGGKITSYRHVAEEAVDALARHVPALTGKHWTAKAALPGGDFPMTGA
AALAAEYRSAHPFLAATTAERIARAYGTGARRWLGDAGDWDALGGEIAHGLSVAEVEWMVEQEWARTADDILWRRSKLGL
VFGEEDKARFAATLRELQ

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=517, Percent_Identity=29.4003868471954, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI285002231, Length=517, Percent_Identity=29.4003868471954, Blast_Score=168, Evalue=1e-41,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=46.5811965811966, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1788574, Length=505, Percent_Identity=27.9207920792079, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115534726, Length=505, Percent_Identity=30.0990099009901, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17509253, Length=503, Percent_Identity=30.6163021868787, Blast_Score=141, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6322036, Length=555, Percent_Identity=27.5675675675676, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI161077125, Length=505, Percent_Identity=28.7128712871287, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24653942, Length=505, Percent_Identity=28.7128712871287, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24653944, Length=505, Percent_Identity=28.7128712871287, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI20130025, Length=505, Percent_Identity=28.7128712871287, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24586295, Length=505, Percent_Identity=27.7227722772277, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI19921278, Length=505, Percent_Identity=26.5346534653465, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55193; Mature: 55062

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTPPPYDIIVVGGGVNGAGVARDAAGRGARVLLLEAGDLAQGTSSKSTKLIHGGLRYL
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
EHYEFTLVREALKEREVLWSIAPHIIRPMRFVLPYRDGLRPRWLLRLGLFLYDHIGGRRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
LPGTRSIDLRRHVAGAPLQSHYVHGFEYSDGWVDDARLVLLNARDAADRGARVRTRTRAE
CCCCCCCHHHHHHCCCCHHHHCEECEECCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHH
MLRCDGGLWVVDAADDQGHRYRFTGRSVVNAAGPAVLDLLKRADAEPDHQMRLVRGSHIV
HHHCCCCEEEEECCCCCCCEEEECCCHHHHCCCHHHHHHHHHCCCCCCHHEEEECCCHHH
VRRLFEHHYSYFFQLPDGRIFFAIPYEHDFTLIGTTDVDHDGPASEAQASEAEIAYLCEG
HHHHHHHHCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
ASLYFRTPVTPADVVWTYSGVRPLVEDGSGRPEAATRGYRIDLDMEEGAPLLTIYGGKIT
CEEEEECCCCCHHEEEEECCCCHHHHCCCCCCCHHCCCEEEEEECCCCCCEEEEECCCCC
SYRHVAEEAVDALARHVPALTGKHWTAKAALPGGDFPMTGAAALAAEYRSAHPFLAATTA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHH
ERIARAYGTGARRWLGDAGDWDALGGEIAHGLSVAEVEWMVEQEWARTADDILWRRSKLG
HHHHHHHCCCHHHHCCCCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LVFGEEDKARFAATLRELQ
EEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ADTPPPYDIIVVGGGVNGAGVARDAAGRGARVLLLEAGDLAQGTSSKSTKLIHGGLRYL
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
EHYEFTLVREALKEREVLWSIAPHIIRPMRFVLPYRDGLRPRWLLRLGLFLYDHIGGRRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
LPGTRSIDLRRHVAGAPLQSHYVHGFEYSDGWVDDARLVLLNARDAADRGARVRTRTRAE
CCCCCCCHHHHHHCCCCHHHHCEECEECCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHH
MLRCDGGLWVVDAADDQGHRYRFTGRSVVNAAGPAVLDLLKRADAEPDHQMRLVRGSHIV
HHHCCCCEEEEECCCCCCCEEEECCCHHHHCCCHHHHHHHHHCCCCCCHHEEEECCCHHH
VRRLFEHHYSYFFQLPDGRIFFAIPYEHDFTLIGTTDVDHDGPASEAQASEAEIAYLCEG
HHHHHHHHCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
ASLYFRTPVTPADVVWTYSGVRPLVEDGSGRPEAATRGYRIDLDMEEGAPLLTIYGGKIT
CEEEEECCCCCHHEEEEECCCCHHHHCCCCCCCHHCCCEEEEEECCCCCCEEEEECCCCC
SYRHVAEEAVDALARHVPALTGKHWTAKAALPGGDFPMTGAAALAAEYRSAHPFLAATTA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEHHHH
ERIARAYGTGARRWLGDAGDWDALGGEIAHGLSVAEVEWMVEQEWARTADDILWRRSKLG
HHHHHHHCCCHHHHCCCCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LVFGEEDKARFAATLRELQ
EEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]