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The map label for this gene is gdhB [H]

Identifier: 103485649

GI number: 103485649

Start: 147432

End: 148898

Strand: Direct

Name: gdhB [H]

Synonym: Sala_0153

Alternate gene names: 103485649

Gene position: 147432-148898 (Clockwise)

Preceding gene: 103485646

Following gene: 103485650

Centisome position: 4.41

GC content: 65.37

Gene sequence:

>1467_bases
ATGCCGAAGCATATTTTTGCCCTGCTGTTTTTGCTTGCATTGACATCGTGCGGAGGTGGTGGGGGAGGCGATACGCCGCC
GCCGTTGGCCAACACGCCGCCCGTATTCACCTCACTCCAGACCGCCAGCGTCGCCGAGAACACGGCGAACGCCTATCAGG
CGGCGGCAAGCGATGCCGACGGCGACGCGCTGACCTTCGCCATCGACGGCGGCGCCGATGCGGCGCGCTTTGCGATCACC
GGCGCGGGCGCATTGCGGTTCAACACGCCGCCCGATTTCGACCTGCCCGGCGATGCCGATGGCGACAATGTCTATGCCGT
CGTGCTGCGCGTCAGCGATGGCCGGGCGAGCGTGACACAGGCGGTCAACATCACCGTCACCAACAGCCGCGAAGGGATCG
CCGTCGCGCGCGTCGGAACGGGGTTCAGCCAGCCGCTTTATGTCGCGCCGATCCCCGGCGACAATCGCATCTATGTGGTC
GAAAAGGGCGGCGACGTCTATCGTTTCGACCCCGCGGACGGCAGCCGGACGCGCGTGCTCGACATTACCGACATTTCGAC
GAGCGGCGAGCGCGGCCTGCTTGGCCTTGCGCCCTATCCCGACCATGCAACCTCGCAGCGCCTGTTCGCGGTCGCCACGG
CGATCAACGGCAATGTCCAGGTGCGGCGCTACACGCTGGGCCAGCCGAATAGTTCGACCAGTTACGACCTCGTGCTCGAC
ATTCCGCATCCCGGTTTCGACAATCATAATGGCGGCTGGATCGGCTTCGGCCCCGACGGCCATGTCTATGTCGCGGTCGG
AGACGGCGGCGGCGCGGGCGACCCCAACAACAATGCGCAAAACCGCAATGTACAGCTTGGCAAGATCCTGCGCTTCGCGG
TGGGCACCGGGGGCAGCACCTATGCCCCGGCACCGGGCAACCCCTTTCTTGCGGGCGGCGGCGATCCCTATGTCTTTGCG
CTTGGCCTGCGCAACCCGTTCCGCGCCTCCTTTTCGGGGTCGACGCTGCTGATCGGCGATGTCGGGCAGAATGCGGTCGA
GGAAATCGACATGGTCGCGACGGCACAGCCGGGGCTCAACTTTGGCTGGCGCTTCCTGGAAGGCACGCAGCCCTTTTCGG
GAACGGCGCCTGCGGGCCTGACCCCGCCCGTCGCCGAATATGGCCATGGCAGCGGTCCGCGTCAGGGGCGTTCGGTCACC
GGCGGCTATGTCTACCGTGGACCGGTGGCCTCGTTGCAGGGCCAGTATGTCTTTGGCGATTTCGTGTCGGGCAATATATG
GACCGTGCCCTTTGCCGACCTCGTTGCCGGTCAGACCTTGCCCGCGGCCCGCTTTGCCGTGCGCAACGAGGATTTTGCTC
CCGACGCAGGAACGATAGCCAACATCGCCTCATTCGGCGAGGACAGCGCGGGCAATCTGTTCATCGTCAGCATCGGCGGC
GACATTTTCATGGTGCGGCCGGGCTGA

Upstream 100 bases:

>100_bases
CGGACGGCGCGGGCGATGGTAAACGGGGCGAGGTTGCGGACCCGCCCGTGCGGTGGCAGTTTGCGTCGGGGTGGGCCCGA
TCGCGAAAGGCTGGTCGCCG

Downstream 100 bases:

>100_bases
CCGTCCCGCGGCGGCCGCCGATTCCCGTCATCGGGATGCCATGGGATGCCATGCCTTTCGCACGAAAAGCCTGGCCCGCC
GATTTTCGCCGTTGGCCGCG

Product: glucose/sorbosone dehydrogenases-like protein

Products: NA

Alternate protein names: Glucose dehydrogenase B [pyrroloquinoline-quinone]; Soluble glucose dehydrogenase; s-GDH [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MPKHIFALLFLLALTSCGGGGGGDTPPPLANTPPVFTSLQTASVAENTANAYQAAASDADGDALTFAIDGGADAARFAIT
GAGALRFNTPPDFDLPGDADGDNVYAVVLRVSDGRASVTQAVNITVTNSREGIAVARVGTGFSQPLYVAPIPGDNRIYVV
EKGGDVYRFDPADGSRTRVLDITDISTSGERGLLGLAPYPDHATSQRLFAVATAINGNVQVRRYTLGQPNSSTSYDLVLD
IPHPGFDNHNGGWIGFGPDGHVYVAVGDGGGAGDPNNNAQNRNVQLGKILRFAVGTGGSTYAPAPGNPFLAGGGDPYVFA
LGLRNPFRASFSGSTLLIGDVGQNAVEEIDMVATAQPGLNFGWRFLEGTQPFSGTAPAGLTPPVAEYGHGSGPRQGRSVT
GGYVYRGPVASLQGQYVFGDFVSGNIWTVPFADLVAGQTLPAARFAVRNEDFAPDAGTIANIASFGEDSAGNLFIVSIGG
DIFMVRPG

Sequences:

>Translated_488_residues
MPKHIFALLFLLALTSCGGGGGGDTPPPLANTPPVFTSLQTASVAENTANAYQAAASDADGDALTFAIDGGADAARFAIT
GAGALRFNTPPDFDLPGDADGDNVYAVVLRVSDGRASVTQAVNITVTNSREGIAVARVGTGFSQPLYVAPIPGDNRIYVV
EKGGDVYRFDPADGSRTRVLDITDISTSGERGLLGLAPYPDHATSQRLFAVATAINGNVQVRRYTLGQPNSSTSYDLVLD
IPHPGFDNHNGGWIGFGPDGHVYVAVGDGGGAGDPNNNAQNRNVQLGKILRFAVGTGGSTYAPAPGNPFLAGGGDPYVFA
LGLRNPFRASFSGSTLLIGDVGQNAVEEIDMVATAQPGLNFGWRFLEGTQPFSGTAPAGLTPPVAEYGHGSGPRQGRSVT
GGYVYRGPVASLQGQYVFGDFVSGNIWTVPFADLVAGQTLPAARFAVRNEDFAPDAGTIANIASFGEDSAGNLFIVSIGG
DIFMVRPG
>Mature_487_residues
PKHIFALLFLLALTSCGGGGGGDTPPPLANTPPVFTSLQTASVAENTANAYQAAASDADGDALTFAIDGGADAARFAITG
AGALRFNTPPDFDLPGDADGDNVYAVVLRVSDGRASVTQAVNITVTNSREGIAVARVGTGFSQPLYVAPIPGDNRIYVVE
KGGDVYRFDPADGSRTRVLDITDISTSGERGLLGLAPYPDHATSQRLFAVATAINGNVQVRRYTLGQPNSSTSYDLVLDI
PHPGFDNHNGGWIGFGPDGHVYVAVGDGGGAGDPNNNAQNRNVQLGKILRFAVGTGGSTYAPAPGNPFLAGGGDPYVFAL
GLRNPFRASFSGSTLLIGDVGQNAVEEIDMVATAQPGLNFGWRFLEGTQPFSGTAPAGLTPPVAEYGHGSGPRQGRSVTG
GYVYRGPVASLQGQYVFGDFVSGNIWTVPFADLVAGQTLPAARFAVRNEDFAPDAGTIANIASFGEDSAGNLFIVSIGGD
IFMVRPG

Specific function: Oxidizes glucose to gluconolactone [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936953, Length=394, Percent_Identity=34.2639593908629, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI187936955, Length=394, Percent_Identity=34.2639593908629, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI124248546, Length=392, Percent_Identity=32.9081632653061, Blast_Score=162, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR019893
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 50319; Mature: 50188

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00018 EF_HAND_1 ; PS50268 CADHERIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKHIFALLFLLALTSCGGGGGGDTPPPLANTPPVFTSLQTASVAENTANAYQAAASDAD
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCC
GDALTFAIDGGADAARFAITGAGALRFNTPPDFDLPGDADGDNVYAVVLRVSDGRASVTQ
CCEEEEEEECCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEE
AVNITVTNSREGIAVARVGTGFSQPLYVAPIPGDNRIYVVEKGGDVYRFDPADGSRTRVL
EEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCCCEEEECCCCCCCEEEE
DITDISTSGERGLLGLAPYPDHATSQRLFAVATAINGNVQVRRYTLGQPNSSTSYDLVLD
EEEECCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEE
IPHPGFDNHNGGWIGFGPDGHVYVAVGDGGGAGDPNNNAQNRNVQLGKILRFAVGTGGST
CCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEHHEEEEEEECCCCCE
YAPAPGNPFLAGGGDPYVFALGLRNPFRASFSGSTLLIGDVGQNAVEEIDMVATAQPGLN
ECCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHEEEECCCCCC
FGWRFLEGTQPFSGTAPAGLTPPVAEYGHGSGPRQGRSVTGGYVYRGPVASLQGQYVFGD
CCEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCEEEEE
FVSGNIWTVPFADLVAGQTLPAARFAVRNEDFAPDAGTIANIASFGEDSAGNLFIVSIGG
ECCCCEEEECHHHHHCCCCCCHHHEEECCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECC
DIFMVRPG
CEEEECCC
>Mature Secondary Structure 
PKHIFALLFLLALTSCGGGGGGDTPPPLANTPPVFTSLQTASVAENTANAYQAAASDAD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCC
GDALTFAIDGGADAARFAITGAGALRFNTPPDFDLPGDADGDNVYAVVLRVSDGRASVTQ
CCEEEEEEECCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEE
AVNITVTNSREGIAVARVGTGFSQPLYVAPIPGDNRIYVVEKGGDVYRFDPADGSRTRVL
EEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEECCCCEEEECCCCCCCEEEE
DITDISTSGERGLLGLAPYPDHATSQRLFAVATAINGNVQVRRYTLGQPNSSTSYDLVLD
EEEECCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEE
IPHPGFDNHNGGWIGFGPDGHVYVAVGDGGGAGDPNNNAQNRNVQLGKILRFAVGTGGST
CCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEHHEEEEEEECCCCCE
YAPAPGNPFLAGGGDPYVFALGLRNPFRASFSGSTLLIGDVGQNAVEEIDMVATAQPGLN
ECCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHEEEECCCCCC
FGWRFLEGTQPFSGTAPAGLTPPVAEYGHGSGPRQGRSVTGGYVYRGPVASLQGQYVFGD
CCEEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCEEEEE
FVSGNIWTVPFADLVAGQTLPAARFAVRNEDFAPDAGTIANIASFGEDSAGNLFIVSIGG
ECCCCEEEECHHHHHCCCCCCHHHEEECCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECC
DIFMVRPG
CEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2671663; 10366508; 10508152 [H]