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The map label for this gene is msrA [H]

Identifier: 103485613

GI number: 103485613

Start: 114425

End: 115027

Strand: Direct

Name: msrA [H]

Synonym: Sala_0117

Alternate gene names: 103485613

Gene position: 114425-115027 (Clockwise)

Preceding gene: 103485612

Following gene: 103485614

Centisome position: 3.42

GC content: 57.88

Gene sequence:

>603_bases
ATGGCGAAGATCGGCTTTGGAGGGGGGTGCCATTGGTGCACCGAAGGGGTGTTCCAGGCGCTGCGCGGCGTTGCGCAGGT
CGACCAGGGCTTTGTCCAATCGGACGCTCCGGCAGATAGCTGGTCAGAAGGGGTGATCGTCACCTTCGATCCTTCAATCA
TTCCGTTGGCAACGCTGTGCGAGGTGCATCTGAGAACGCATTCAGCCACCCGGGCCCGCTCTCCTAGCGACAAGTACCGC
AGCGCGATCTATATTTTCGATGACAACCAGCGGCATGAGGCCGAACTGGCGATCGTCCGATTTGCCGAGGAATTCGGCAA
TACGGCGCATACCCTGGTTCTGCCGTTCAGAAGCTTCAAGGCTTCGGACGAGCGTTACCAGAACTATTATCGAACCGATC
CGAGCCGACCCTTCTGCCGCCGCTTCATCGATCCCAAGCTGGACTATATTCGGCAGCATTTTTCGGAAGTGGCCCTGCCT
GAACCGAACTCTGTCGCCGAGCACGCTGTCGATCGCGACAATGTCTCGCAAGACCCCGCCAGCGCTGGGATAATGACTGA
CAGTTCTTCATCCATCGCAACTCAATCAAGGACGTCGCCATGA

Upstream 100 bases:

>100_bases
CGCTGATGCTTACATTGATTGCGTCCGCAGCCAGAAGGCTCAGGCGCGCGAGACGGCGCTGATCCGCGGAAAGAAATACG
TCTAGGCGCGAGAGGTGAAG

Downstream 100 bases:

>100_bases
TGATCAAAAAGCCATTCACTATTCTCCCTCTCGCCCTGGCGCTGCTTGGCCCGATATCCTCTTCTCCCGGTTTAGCGGCT
CCGACGCCCGCCGCGGTGCC

Product: methionine sulfoxide reductase A

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase; Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MAKIGFGGGCHWCTEGVFQALRGVAQVDQGFVQSDAPADSWSEGVIVTFDPSIIPLATLCEVHLRTHSATRARSPSDKYR
SAIYIFDDNQRHEAELAIVRFAEEFGNTAHTLVLPFRSFKASDERYQNYYRTDPSRPFCRRFIDPKLDYIRQHFSEVALP
EPNSVAEHAVDRDNVSQDPASAGIMTDSSSSIATQSRTSP

Sequences:

>Translated_200_residues
MAKIGFGGGCHWCTEGVFQALRGVAQVDQGFVQSDAPADSWSEGVIVTFDPSIIPLATLCEVHLRTHSATRARSPSDKYR
SAIYIFDDNQRHEAELAIVRFAEEFGNTAHTLVLPFRSFKASDERYQNYYRTDPSRPFCRRFIDPKLDYIRQHFSEVALP
EPNSVAEHAVDRDNVSQDPASAGIMTDSSSSIATQSRTSP
>Mature_199_residues
AKIGFGGGCHWCTEGVFQALRGVAQVDQGFVQSDAPADSWSEGVIVTFDPSIIPLATLCEVHLRTHSATRARSPSDKYRS
AIYIFDDNQRHEAELAIVRFAEEFGNTAHTLVLPFRSFKASDERYQNYYRTDPSRPFCRRFIDPKLDYIRQHFSEVALPE
PNSVAEHAVDRDNVSQDPASAGIMTDSSSSIATQSRTSP

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 22303; Mature: 22172

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIGFGGGCHWCTEGVFQALRGVAQVDQGFVQSDAPADSWSEGVIVTFDPSIIPLATLC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHH
EVHLRTHSATRARSPSDKYRSAIYIFDDNQRHEAELAIVRFAEEFGNTAHTLVLPFRSFK
HHHHHHCCHHHCCCCCHHHCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHC
ASDERYQNYYRTDPSRPFCRRFIDPKLDYIRQHFSEVALPEPNSVAEHAVDRDNVSQDPA
CCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCC
SAGIMTDSSSSIATQSRTSP
CCCEEECCCCCHHCCCCCCC
>Mature Secondary Structure 
AKIGFGGGCHWCTEGVFQALRGVAQVDQGFVQSDAPADSWSEGVIVTFDPSIIPLATLC
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHH
EVHLRTHSATRARSPSDKYRSAIYIFDDNQRHEAELAIVRFAEEFGNTAHTLVLPFRSFK
HHHHHHCCHHHCCCCCHHHCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHC
ASDERYQNYYRTDPSRPFCRRFIDPKLDYIRQHFSEVALPEPNSVAEHAVDRDNVSQDPA
CCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCC
SAGIMTDSSSSIATQSRTSP
CCCEEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]