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The map label for this gene is oxyR [H]

Identifier: 103485593

GI number: 103485593

Start: 97276

End: 98235

Strand: Direct

Name: oxyR [H]

Synonym: Sala_0095

Alternate gene names: 103485593

Gene position: 97276-98235 (Clockwise)

Preceding gene: 103485592

Following gene: 103485594

Centisome position: 2.91

GC content: 60.31

Gene sequence:

>960_bases
ATGCGTCGCGCATACTTATTTCGCCTCTCCCAGGAACGCGGTCTTTCGGAAGAAGCATCAGTCAGGCGCATGGATCGACG
GACTATGGAACTCAATCAGGTCAGCTATTTCATCAACTTGGCCAAGACGCTGAATTTTACAGCGGCCGCTCGCCTGAGCG
GTGTGTCGCAGCCGAGCCTGACCCGCGCAATCCGCCGCTTGGAAGAGGAGCTCGGCGGGCCGCTGATTCACCGCGACGGG
AAAAACAGTCGCCTGACCGGCCTTGGCCGGGACGTCGAGACAGAATTCCGGCGCATGCTGGTGGCGATGCGAAGCGTCCG
CAATCATTCCGAGAACTGGGCGATGGGGATGCACCGTGTTCTGGATGTGGCGGTCGCGCCGACTGTCGGACCGCAGGAGT
TTGCCGCGTTTTTCGAGAGCGCGTTGGCGGAGGTGCCATCCATTGAAATCAAGCTGCACTCGCTTCAGCCGAACGAGGAC
ACCTCGGACATTCTGTCCGGAAAATATCATGCGTGCATCATGCCGCGCGAGACAAGGCCGGAGCCTAAGCTCGATGTGCA
TCCGCTATTCAGAGAGCGCTTCGTACTGGGCTGTTCTGCGAGCCATCCCTTGGCATCCCGCGAAATCGTGCGCGGAGAAG
ACCTGCTCGAGTTTCCTTTCGTCGATCGCCTCAAGTGCGAGTTTCGCGATCAGATCCTCGATCATTTCGCGCGGCACGAC
CTGCTCATGCAGCCCCGCTTTCGATCGGACCGCGAGGACTGGGTGCAACACTTCGTCGCCGATGGCACCGCCATATGCAT
TCTTCCGGAACGATCCGCCACGGCGCCCGGTCTTGTTACGCGGCCGATCGAGGGATTTGCCCTGGAGCGCGAAGTCGTGA
TCGCGACGGTATCTGGCTCCACCGCACCCGTCGAGATACGGAAGATCGCGCAACTGGCAGCCGGATATGCGTGGCACTAA

Upstream 100 bases:

>100_bases
TTCGGCAGCCCGAGCGCACGGCCACGGCCACGGCTACGCATCGCATCGCGTATAAAATATATGCGCCGCGCATATAGACA
AAGCTGCACACTATGATTAT

Downstream 100 bases:

>100_bases
ACCCCGTCGCGAGAGCGTCGGTGCTATGGAAACTATAGGCACAGCCTATTGGATAAATCCTAGGCGCACTGCGATAGTCG
GCGCAGTGACTGACACGATA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRRAYLFRLSQERGLSEEASVRRMDRRTMELNQVSYFINLAKTLNFTAAARLSGVSQPSLTRAIRRLEEELGGPLIHRDG
KNSRLTGLGRDVETEFRRMLVAMRSVRNHSENWAMGMHRVLDVAVAPTVGPQEFAAFFESALAEVPSIEIKLHSLQPNED
TSDILSGKYHACIMPRETRPEPKLDVHPLFRERFVLGCSASHPLASREIVRGEDLLEFPFVDRLKCEFRDQILDHFARHD
LLMQPRFRSDREDWVQHFVADGTAICILPERSATAPGLVTRPIEGFALEREVVIATVSGSTAPVEIRKIAQLAAGYAWH

Sequences:

>Translated_319_residues
MRRAYLFRLSQERGLSEEASVRRMDRRTMELNQVSYFINLAKTLNFTAAARLSGVSQPSLTRAIRRLEEELGGPLIHRDG
KNSRLTGLGRDVETEFRRMLVAMRSVRNHSENWAMGMHRVLDVAVAPTVGPQEFAAFFESALAEVPSIEIKLHSLQPNED
TSDILSGKYHACIMPRETRPEPKLDVHPLFRERFVLGCSASHPLASREIVRGEDLLEFPFVDRLKCEFRDQILDHFARHD
LLMQPRFRSDREDWVQHFVADGTAICILPERSATAPGLVTRPIEGFALEREVVIATVSGSTAPVEIRKIAQLAAGYAWH
>Mature_319_residues
MRRAYLFRLSQERGLSEEASVRRMDRRTMELNQVSYFINLAKTLNFTAAARLSGVSQPSLTRAIRRLEEELGGPLIHRDG
KNSRLTGLGRDVETEFRRMLVAMRSVRNHSENWAMGMHRVLDVAVAPTVGPQEFAAFFESALAEVPSIEIKLHSLQPNED
TSDILSGKYHACIMPRETRPEPKLDVHPLFRERFVLGCSASHPLASREIVRGEDLLEFPFVDRLKCEFRDQILDHFARHD
LLMQPRFRSDREDWVQHFVADGTAICILPERSATAPGLVTRPIEGFALEREVVIATVSGSTAPVEIRKIAQLAAGYAWH

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=243, Percent_Identity=27.9835390946502, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI157672245, Length=206, Percent_Identity=31.5533980582524, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=203, Percent_Identity=26.6009852216749, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788296, Length=232, Percent_Identity=27.1551724137931, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=195, Percent_Identity=29.2307692307692, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36197; Mature: 36197

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAYLFRLSQERGLSEEASVRRMDRRTMELNQVSYFINLAKTLNFTAAARLSGVSQPSL
CCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHH
TRAIRRLEEELGGPLIHRDGKNSRLTGLGRDVETEFRRMLVAMRSVRNHSENWAMGMHRV
HHHHHHHHHHHCCCEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDVAVAPTVGPQEFAAFFESALAEVPSIEIKLHSLQPNEDTSDILSGKYHACIMPRETRP
HHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEECCCCCCC
EPKLDVHPLFRERFVLGCSASHPLASREIVRGEDLLEFPFVDRLKCEFRDQILDHFARHD
CCCCCCCHHHHHHEEECCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LLMQPRFRSDREDWVQHFVADGTAICILPERSATAPGLVTRPIEGFALEREVVIATVSGS
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCCEECCEEEEEEECCC
TAPVEIRKIAQLAAGYAWH
CCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRRAYLFRLSQERGLSEEASVRRMDRRTMELNQVSYFINLAKTLNFTAAARLSGVSQPSL
CCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHH
TRAIRRLEEELGGPLIHRDGKNSRLTGLGRDVETEFRRMLVAMRSVRNHSENWAMGMHRV
HHHHHHHHHHHCCCEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDVAVAPTVGPQEFAAFFESALAEVPSIEIKLHSLQPNEDTSDILSGKYHACIMPRETRP
HHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEECCCCCCC
EPKLDVHPLFRERFVLGCSASHPLASREIVRGEDLLEFPFVDRLKCEFRDQILDHFARHD
CCCCCCCHHHHHHEEECCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
LLMQPRFRSDREDWVQHFVADGTAICILPERSATAPGLVTRPIEGFALEREVVIATVSGS
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCCEECCEEEEEEECCC
TAPVEIRKIAQLAAGYAWH
CCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]