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The map label for this gene is zntR [H]

Identifier: 99082771

GI number: 99082771

Start: 3099944

End: 3100360

Strand: Direct

Name: zntR [H]

Synonym: TM1040_2931

Alternate gene names: 99082771

Gene position: 3099944-3100360 (Clockwise)

Preceding gene: 99082768

Following gene: 99082773

Centisome position: 96.84

GC content: 58.27

Gene sequence:

>417_bases
ATGCTGTCCATTGGTGCATTGTCCAAGGCCACCGGGGTCAAGGTTCCGACCATTCGCTATTACGAAGAGATCGGTTTGAT
CGACCATGCCAGTAGAAATGCCGGCAATCAAAGGCGCTACGATCAGGCGGGGCTGGAGCGGCTTGGCTTTATCAAACATG
CCCGCGATCTCGGTTTTACATTAGAAGAAATCAGGGACTTGATGGGGCTCAACGGGCAGCTGGGCCAGGATTGCAGAGCT
GCCGATCGCATCGCGCAGTCGCAGCTTGAAAAGGTGCGGGCGCGGATCGCGCGCTTACGCCGTCTCGAGGCCGAGTTGGA
GCGGATCACCACCCTGTGCCAAGGTGGCAATGGTGGTCAGTGCCAGGTCCTGAGCGCCTTGGGGGACCATAGCTTGTGCT
TGGGCGACCATGATTGA

Upstream 100 bases:

>100_bases
TGCAGCATCCTGCCATGAGTCAGGTCCTTTGCGCTTCGTCTTGAATTCGATTCGAGAGGAACTTAATTGCTCTAGTGACT
AGAGGTTCAAGGGGGATTTG

Downstream 100 bases:

>100_bases
AGGTGTTGTTTACACGCCGGGTGGATCCGCAGGCGGGACAAATTTCTCCATGTCCTCCGCTGAAAAGACCGCCTGCAATC
CGCTTCGATAATCCGGGTAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MLSIGALSKATGVKVPTIRYYEEIGLIDHASRNAGNQRRYDQAGLERLGFIKHARDLGFTLEEIRDLMGLNGQLGQDCRA
ADRIAQSQLEKVRARIARLRRLEAELERITTLCQGGNGGQCQVLSALGDHSLCLGDHD

Sequences:

>Translated_138_residues
MLSIGALSKATGVKVPTIRYYEEIGLIDHASRNAGNQRRYDQAGLERLGFIKHARDLGFTLEEIRDLMGLNGQLGQDCRA
ADRIAQSQLEKVRARIARLRRLEAELERITTLCQGGNGGQCQVLSALGDHSLCLGDHD
>Mature_138_residues
MLSIGALSKATGVKVPTIRYYEEIGLIDHASRNAGNQRRYDQAGLERLGFIKHARDLGFTLEEIRDLMGLNGQLGQDCRA
ADRIAQSQLEKVRARIARLRRLEAELERITTLCQGGNGGQCQVLSALGDHSLCLGDHD

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=39.2307692307692, Blast_Score=91, Evalue=3e-20,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=26.7716535433071, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15216; Mature: 15216

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIGALSKATGVKVPTIRYYEEIGLIDHASRNAGNQRRYDQAGLERLGFIKHARDLGFT
CCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LEEIRDLMGLNGQLGQDCRAADRIAQSQLEKVRARIARLRRLEAELERITTLCQGGNGGQ
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
CQVLSALGDHSLCLGDHD
CHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLSIGALSKATGVKVPTIRYYEEIGLIDHASRNAGNQRRYDQAGLERLGFIKHARDLGFT
CCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LEEIRDLMGLNGQLGQDCRAADRIAQSQLEKVRARIARLRRLEAELERITTLCQGGNGGQ
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
CQVLSALGDHSLCLGDHD
CHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]