Click here to switch to the map view.

The map label for this gene is yafV [C]

Identifier: 99082744

GI number: 99082744

Start: 3072152

End: 3072985

Strand: Direct

Name: yafV [C]

Synonym: TM1040_2904

Alternate gene names: 99082744

Gene position: 3072152-3072985 (Clockwise)

Preceding gene: 99082743

Following gene: 99082745

Centisome position: 95.98

GC content: 61.03

Gene sequence:

>834_bases
ATGGTTCGGATTGCGCTCCTGCAGATGACGTCTTCCGACTTGCCGGAAGAGAACCTTGCAGCGGCGCGCGAAATGATCGC
GCGCACGGCCGCTGCAGGGGCGCAGTTTGTGTTGACGCCAGAGGTCACCAATTGCCTCTCGACCAGCCGGACACAGCAAC
AGGCTGTTTTGCATCCCGAAGAGAACGACCCCACCCTTGCCGGTCTGCGTGATGCGGCTCGGCAGCATGGGGTTTGGCTG
TCGATCGGCTCTCTTGGGGTGAAAACCACCGATGCGGACGGCCGGTTTGCCAACCGGCAGTTTCTGATTTCCCCCGATGG
CGAGATCAAGGCGCGCTATGACAAGATCCACATGTTTGATGTGGAGGTCACGCCTGAAGAGACCTATCGCGAATCCGATG
GCTACCGCCCTGGAACCCGCGCCGTGCTTGCGGACGCTGGATTTGCAAAGATCGGTATGACGATCTGTTACGATGTGCGC
TTTCCTGCGTTGCATCGTCGTCTTGCCCAAGCCGGGGCAGAAATCATCACGGCGCCGGCTGCCTTCAGTCATGTGACGGG
AGCAGCGCATTGGCACAGCCTCCTGCGGGCGCGGGCGATTGAAACCGGGTGTTTCGTGCTTGCCGCTGCGCAGACGGGGG
TTCACGACACCAGTCGTGGCGCTGCCCGCCAGACCTATGGGCATTCGCTTGCCGTTGCCCCTTGGGGCGAGATTTTGGCG
GATGCTGGCACCGAAACTGGAATTACCTGCGTTGACCTCGATCTCGAAGCGGTGAAAAAGGCGCGCAAACGCGTCCCGTC
TCTGACGCACGACCGGGAGTTTGACGGACCCTGA

Upstream 100 bases:

>100_bases
CCGCAGATCTTTGTTGGCGACATTCACGTGGGCGGTTGTGACGAGCTTCACGCTCTGGACCGGGCAGGGAAGCTCGACTC
GCTGCTGGCGTCCTGATCCG

Downstream 100 bases:

>100_bases
TGGATGAGAAGCATTCCCTTGCGATTTCGCTCTTCAGCGAGATTCTTATGGCGGACCAATTGGCCCGTGCTCGGCTGAGC
AAGGCTCTGCCCAAAGGGAT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MVRIALLQMTSSDLPEENLAAAREMIARTAAAGAQFVLTPEVTNCLSTSRTQQQAVLHPEENDPTLAGLRDAARQHGVWL
SIGSLGVKTTDADGRFANRQFLISPDGEIKARYDKIHMFDVEVTPEETYRESDGYRPGTRAVLADAGFAKIGMTICYDVR
FPALHRRLAQAGAEIITAPAAFSHVTGAAHWHSLLRARAIETGCFVLAAAQTGVHDTSRGAARQTYGHSLAVAPWGEILA
DAGTETGITCVDLDLEAVKKARKRVPSLTHDREFDGP

Sequences:

>Translated_277_residues
MVRIALLQMTSSDLPEENLAAAREMIARTAAAGAQFVLTPEVTNCLSTSRTQQQAVLHPEENDPTLAGLRDAARQHGVWL
SIGSLGVKTTDADGRFANRQFLISPDGEIKARYDKIHMFDVEVTPEETYRESDGYRPGTRAVLADAGFAKIGMTICYDVR
FPALHRRLAQAGAEIITAPAAFSHVTGAAHWHSLLRARAIETGCFVLAAAQTGVHDTSRGAARQTYGHSLAVAPWGEILA
DAGTETGITCVDLDLEAVKKARKRVPSLTHDREFDGP
>Mature_277_residues
MVRIALLQMTSSDLPEENLAAAREMIARTAAAGAQFVLTPEVTNCLSTSRTQQQAVLHPEENDPTLAGLRDAARQHGVWL
SIGSLGVKTTDADGRFANRQFLISPDGEIKARYDKIHMFDVEVTPEETYRESDGYRPGTRAVLADAGFAKIGMTICYDVR
FPALHRRLAQAGAEIITAPAAFSHVTGAAHWHSLLRARAIETGCFVLAAAQTGVHDTSRGAARQTYGHSLAVAPWGEILA
DAGTETGITCVDLDLEAVKKARKRVPSLTHDREFDGP

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=276, Percent_Identity=36.5942028985507, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI297632348, Length=276, Percent_Identity=36.5942028985507, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI5031947, Length=274, Percent_Identity=36.1313868613139, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI9910460, Length=274, Percent_Identity=34.6715328467153, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI297632346, Length=196, Percent_Identity=33.1632653061224, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1786412, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=270, Percent_Identity=36.2962962962963, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=30.8970099667774, Blast_Score=152, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6323383, Length=280, Percent_Identity=31.7857142857143, Blast_Score=142, Evalue=6e-35,
Organism=Drosophila melanogaster, GI17933642, Length=273, Percent_Identity=38.0952380952381, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21355835, Length=278, Percent_Identity=29.8561151079137, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29945; Mature: 29945

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIALLQMTSSDLPEENLAAAREMIARTAAAGAQFVLTPEVTNCLSTSRTQQQAVLHPE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCHHHHHEECCC
ENDPTLAGLRDAARQHGVWLSIGSLGVKTTDADGRFANRQFLISPDGEIKARYDKIHMFD
CCCCHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCCCEEEECCCCCEEEEEEEEEEEE
VEVTPEETYRESDGYRPGTRAVLADAGFAKIGMTICYDVRFPALHRRLAQAGAEIITAPA
EEECCHHHHHCCCCCCCCCCEEEECCCHHHHCEEEEEECCCHHHHHHHHHCCHHEEECCH
AFSHVTGAAHWHSLLRARAIETGCFVLAAAQTGVHDTSRGAARQTYGHSLAVAPWGEILA
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHCCCEEEECCHHHHHH
DAGTETGITCVDLDLEAVKKARKRVPSLTHDREFDGP
CCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVRIALLQMTSSDLPEENLAAAREMIARTAAAGAQFVLTPEVTNCLSTSRTQQQAVLHPE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCHHHHHEECCC
ENDPTLAGLRDAARQHGVWLSIGSLGVKTTDADGRFANRQFLISPDGEIKARYDKIHMFD
CCCCHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCCCEEEECCCCCEEEEEEEEEEEE
VEVTPEETYRESDGYRPGTRAVLADAGFAKIGMTICYDVRFPALHRRLAQAGAEIITAPA
EEECCHHHHHCCCCCCCCCCEEEECCCHHHHCEEEEEECCCHHHHHHHHHCCHHEEECCH
AFSHVTGAAHWHSLLRARAIETGCFVLAAAQTGVHDTSRGAARQTYGHSLAVAPWGEILA
HHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHCCCEEEECCHHHHHH
DAGTETGITCVDLDLEAVKKARKRVPSLTHDREFDGP
CCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]