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The map label for this gene is gltD [H]

Identifier: 99082662

GI number: 99082662

Start: 2987026

End: 2988468

Strand: Direct

Name: gltD [H]

Synonym: TM1040_2822

Alternate gene names: 99082662

Gene position: 2987026-2988468 (Clockwise)

Preceding gene: 99082660

Following gene: 99082663

Centisome position: 93.32

GC content: 60.08

Gene sequence:

>1443_bases
GTGGCCAAGCAACCGATGCTAAAGTTCGTGAAGATCGATCGCGACATGCCCGAAAAACGGGACGCCGAGACGCGCAGAGA
AGACTTCGACGAGATCTATGCTGAATTTGCGGCGGTAAAGGCAGAAGAGCAGGCCAGCCGGTGCAGCCAGTGCGGCGTGC
CATATTGCCAGTCGCATTGTCCGCTCCACAACAATATTCCGGATTGGCTGCGTCTGACGGCGACCGGGCGCCTGGAAGAG
GCCTATGCCACATCGCAGGCGACGAATACCTTCCCTGAAATCTGTGGCCGCATCTGCCCGCAGGACCGTCTCTGTGAAGG
CAACTGCGTGATTGAACAGTCCGGCCACGGCACCGTAACCATTGGTGCAGTCGAGAAATACATCACCGATACCGCGTGGG
ACAAAGGCTGGGTCAAGCCCAACGCCCCGATCGAAGAACGTGCGGAATCCGTCGGTATCATCGGTGCGGGCCCCGGCGGC
CTTGCAGCAGCTGACATGCTGCGCAAGGCAGGCGTGCAGGTCACGGTATATGACCGCTATGACCGCGCTGGCGGGCTGCT
GACCTACGGCATCCCGGGCTTCAAGCTCGAAAAAGAAGTTGTCATGCGCCGCAATCAACTGCTGGCCGACGGTGGCGTCA
CTTTTGTGATGAACTGCAATATCGGCGAGGACATATCTTTTGACGAAATCCGCGCCAAGCATGACGCAGTGATCATTGCA
ACCGGCGTGTACAAATCCCGCGATCTGAACATGCCGGGCTCTGGTGCCAAAGGGATCGTGAAGGCCATCGACTTCCTCAC
AGCCTCCAACCGGGTGGCGAACTTTGGTGACACCGTACCAGAGTATGAGGACGGTACCTTCAACGCCACGGGCAAGAAGG
TTGTCGTGATCGGCGGTGGCGACACCGCGATGGACTGCGTGCGCACCTCGGTGCGTCAGGGCGCCGAGTCGGTGAAATGC
CTCTATCGTCGCGACCGTGCAAACATGCCCGGCTCGCAACGCGAAACCCAGAATGCCGAAGAAGAAGGCGTCGTCTTTGA
ATGGCTCTCCGCCCCAAAAGGCTTCACCGATGCAGACGGCAAGGTCTCGGGCGTCATGGTGCAGAAAATGCGTCTCGGCC
AACCCGATGCCTCTGGCCGTCAGGCCCCCGAGGTCATCGAGGGTGCGGACTATGTCGAAGAAGCAGACCTCGTCATCAAA
GCGCTGGGATTCGAACCCGAAGACCTGCCGACGCTCTGGGGCCAGCCGAACCTGCCGGTCACCCGCTGGGGCACCATCAA
GGCAGAGTTCAAAACCGGCGCGACCAATCTCGATGGGGTTTACGCCGTTGGGGACATTGTGCGCGGCGCGTCGCTGGTGG
TCTGGGCGATCAAGGATGGTCGCGACTGTGCAGAAGCGATCATTGAGCGTTTCAACAACAAGGCCGCCGTCGCCGCCGAG
TAA

Upstream 100 bases:

>100_bases
GGATATTCACAGGTAACACGCGAAATAATAGGTCAGCATTAGTTACCTATGTGAGCGCTACACAAGACCTATCGCCGCCA
GCCAAAAGGAGAGTATCGCC

Downstream 100 bases:

>100_bases
TCAACAGGTTTCCCAAGCGGTCCGGCGCCCCTGACACAAGGCGCGGCGCCACCGCCAGGCAGAGGAGAATGAACATGACA
AAATATGATGAGAACTGGGT

Product: putative oxidoreductase

Products: NA

Alternate protein names: Glutamate synthase subunit beta; GLTS beta chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MAKQPMLKFVKIDRDMPEKRDAETRREDFDEIYAEFAAVKAEEQASRCSQCGVPYCQSHCPLHNNIPDWLRLTATGRLEE
AYATSQATNTFPEICGRICPQDRLCEGNCVIEQSGHGTVTIGAVEKYITDTAWDKGWVKPNAPIEERAESVGIIGAGPGG
LAAADMLRKAGVQVTVYDRYDRAGGLLTYGIPGFKLEKEVVMRRNQLLADGGVTFVMNCNIGEDISFDEIRAKHDAVIIA
TGVYKSRDLNMPGSGAKGIVKAIDFLTASNRVANFGDTVPEYEDGTFNATGKKVVVIGGGDTAMDCVRTSVRQGAESVKC
LYRRDRANMPGSQRETQNAEEEGVVFEWLSAPKGFTDADGKVSGVMVQKMRLGQPDASGRQAPEVIEGADYVEEADLVIK
ALGFEPEDLPTLWGQPNLPVTRWGTIKAEFKTGATNLDGVYAVGDIVRGASLVVWAIKDGRDCAEAIIERFNNKAAVAAE

Sequences:

>Translated_480_residues
MAKQPMLKFVKIDRDMPEKRDAETRREDFDEIYAEFAAVKAEEQASRCSQCGVPYCQSHCPLHNNIPDWLRLTATGRLEE
AYATSQATNTFPEICGRICPQDRLCEGNCVIEQSGHGTVTIGAVEKYITDTAWDKGWVKPNAPIEERAESVGIIGAGPGG
LAAADMLRKAGVQVTVYDRYDRAGGLLTYGIPGFKLEKEVVMRRNQLLADGGVTFVMNCNIGEDISFDEIRAKHDAVIIA
TGVYKSRDLNMPGSGAKGIVKAIDFLTASNRVANFGDTVPEYEDGTFNATGKKVVVIGGGDTAMDCVRTSVRQGAESVKC
LYRRDRANMPGSQRETQNAEEEGVVFEWLSAPKGFTDADGKVSGVMVQKMRLGQPDASGRQAPEVIEGADYVEEADLVIK
ALGFEPEDLPTLWGQPNLPVTRWGTIKAEFKTGATNLDGVYAVGDIVRGASLVVWAIKDGRDCAEAIIERFNNKAAVAAE
>Mature_479_residues
AKQPMLKFVKIDRDMPEKRDAETRREDFDEIYAEFAAVKAEEQASRCSQCGVPYCQSHCPLHNNIPDWLRLTATGRLEEA
YATSQATNTFPEICGRICPQDRLCEGNCVIEQSGHGTVTIGAVEKYITDTAWDKGWVKPNAPIEERAESVGIIGAGPGGL
AAADMLRKAGVQVTVYDRYDRAGGLLTYGIPGFKLEKEVVMRRNQLLADGGVTFVMNCNIGEDISFDEIRAKHDAVIIAT
GVYKSRDLNMPGSGAKGIVKAIDFLTASNRVANFGDTVPEYEDGTFNATGKKVVVIGGGDTAMDCVRTSVRQGAESVKCL
YRRDRANMPGSQRETQNAEEEGVVFEWLSAPKGFTDADGKVSGVMVQKMRLGQPDASGRQAPEVIEGADYVEEADLVIKA
LGFEPEDLPTLWGQPNLPVTRWGTIKAEFKTGATNLDGVYAVGDIVRGASLVVWAIKDGRDCAEAIIERFNNKAAVAAE

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=455, Percent_Identity=25.4945054945055, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI1788811, Length=468, Percent_Identity=45.2991452991453, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1789606, Length=473, Percent_Identity=44.3974630021142, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI87082180, Length=469, Percent_Identity=42.0042643923241, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1789243, Length=433, Percent_Identity=31.8706697459584, Blast_Score=168, Evalue=9e-43,
Organism=Escherichia coli, GI1788468, Length=441, Percent_Identity=28.5714285714286, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17570289, Length=499, Percent_Identity=37.2745490981964, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71984108, Length=451, Percent_Identity=26.1640798226164, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17543860, Length=162, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320030, Length=488, Percent_Identity=37.5, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI28574881, Length=483, Percent_Identity=38.7163561076605, Blast_Score=289, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24665539, Length=483, Percent_Identity=38.7163561076605, Blast_Score=289, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24665547, Length=483, Percent_Identity=38.7163561076605, Blast_Score=288, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24665543, Length=483, Percent_Identity=38.7163561076605, Blast_Score=288, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24640763, Length=462, Percent_Identity=25.5411255411255, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI18858217, Length=462, Percent_Identity=25.5411255411255, Blast_Score=130, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 52176; Mature: 52045

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQPMLKFVKIDRDMPEKRDAETRREDFDEIYAEFAAVKAEEQASRCSQCGVPYCQSHC
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PLHNNIPDWLRLTATGRLEEAYATSQATNTFPEICGRICPQDRLCEGNCVIEQSGHGTVT
CCCCCCCHHEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCEEE
IGAVEKYITDTAWDKGWVKPNAPIEERAESVGIIGAGPGGLAAADMLRKAGVQVTVYDRY
EHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCEEECCCCHHHHHHHHHHCCCEEEEEECC
DRAGGLLTYGIPGFKLEKEVVMRRNQLLADGGVTFVMNCNIGEDISFDEIRAKHDAVIIA
CCCCCEEEECCCCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCCCHHHHHCCCCEEEEE
TGVYKSRDLNMPGSGAKGIVKAIDFLTASNRVANFGDTVPEYEDGTFNATGKKVVVIGGG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEECCC
DTAMDCVRTSVRQGAESVKCLYRRDRANMPGSQRETQNAEEEGVVFEWLSAPKGFTDADG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCC
KVSGVMVQKMRLGQPDASGRQAPEVIEGADYVEEADLVIKALGFEPEDLPTLWGQPNLPV
CCHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
TRWGTIKAEFKTGATNLDGVYAVGDIVRGASLVVWAIKDGRDCAEAIIERFNNKAAVAAE
EECCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure 
AKQPMLKFVKIDRDMPEKRDAETRREDFDEIYAEFAAVKAEEQASRCSQCGVPYCQSHC
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
PLHNNIPDWLRLTATGRLEEAYATSQATNTFPEICGRICPQDRLCEGNCVIEQSGHGTVT
CCCCCCCHHEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCEEE
IGAVEKYITDTAWDKGWVKPNAPIEERAESVGIIGAGPGGLAAADMLRKAGVQVTVYDRY
EHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCEEECCCCHHHHHHHHHHCCCEEEEEECC
DRAGGLLTYGIPGFKLEKEVVMRRNQLLADGGVTFVMNCNIGEDISFDEIRAKHDAVIIA
CCCCCEEEECCCCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCCCHHHHHCCCCEEEEE
TGVYKSRDLNMPGSGAKGIVKAIDFLTASNRVANFGDTVPEYEDGTFNATGKKVVVIGGG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEECCC
DTAMDCVRTSVRQGAESVKCLYRRDRANMPGSQRETQNAEEEGVVFEWLSAPKGFTDADG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCC
KVSGVMVQKMRLGQPDASGRQAPEVIEGADYVEEADLVIKALGFEPEDLPTLWGQPNLPV
CCHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
TRWGTIKAEFKTGATNLDGVYAVGDIVRGASLVVWAIKDGRDCAEAIIERFNNKAAVAAE
EECCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428988; 2198943 [H]