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The map label for this gene is azlB [H]

Identifier: 99082578

GI number: 99082578

Start: 2883257

End: 2883715

Strand: Direct

Name: azlB [H]

Synonym: TM1040_2738

Alternate gene names: 99082578

Gene position: 2883257-2883715 (Clockwise)

Preceding gene: 99082575

Following gene: 99082586

Centisome position: 90.08

GC content: 57.95

Gene sequence:

>459_bases
ATGGACTCAAAGGATCGCCAGATCATTCGCGTGCTGCAGGCCAAGGGCCGGATGACCAATCAGGACCTGGCCGAGGCCGT
GAACCTGTCGCCCTCGCCCTGCCTGCGCCGGGTCAAGAACCTGGAAACCGCCGGGGTAATCCGGGGCTACAGCGCCGATG
TGGACGCCCGTGCCTACGGGTTGCCGATCACGGTATTTGTCCGCATCAAGCTAGAACGCCACAACGAGGAAGATGTCCGA
AGTTTTGAGCGCCGGGTGCAGATGATCGACGAGGTGCTCGAATGTCACATCCTGACCGGAGCCACAGATTATCAACTGCG
GGTGGTGGTCGCGGATCTCGATGCCTATGAGGATTTTATCCGCAATCGTATCCACCCCATCGGCGGGATCGCCTCCATTG
ATACCAGTTTTGTCTATAGCACCGTGAAGAATACATCGGTCTTTCCACGGCTGGGATAA

Upstream 100 bases:

>100_bases
CTCATTTGCCTGCCATGATGCGCCTCCACACAGGGCGAGAGATTGCAAAAACTACCAATGCGAGACATGATATTGGCAGA
TTATGCCAATAGGTGACGAT

Downstream 100 bases:

>100_bases
CACCGGGATGACAATGGCCCCGAGCGATCCCCGAGGCCATTGGCTTGCCTTCCGCCTCAGAGGCGCGGCATCAACTCTGC
AAGCGACTTGAACCGGTCAT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MDSKDRQIIRVLQAKGRMTNQDLAEAVNLSPSPCLRRVKNLETAGVIRGYSADVDARAYGLPITVFVRIKLERHNEEDVR
SFERRVQMIDEVLECHILTGATDYQLRVVVADLDAYEDFIRNRIHPIGGIASIDTSFVYSTVKNTSVFPRLG

Sequences:

>Translated_152_residues
MDSKDRQIIRVLQAKGRMTNQDLAEAVNLSPSPCLRRVKNLETAGVIRGYSADVDARAYGLPITVFVRIKLERHNEEDVR
SFERRVQMIDEVLECHILTGATDYQLRVVVADLDAYEDFIRNRIHPIGGIASIDTSFVYSTVKNTSVFPRLG
>Mature_152_residues
MDSKDRQIIRVLQAKGRMTNQDLAEAVNLSPSPCLRRVKNLETAGVIRGYSADVDARAYGLPITVFVRIKLERHNEEDVR
SFERRVQMIDEVLECHILTGATDYQLRVVVADLDAYEDFIRNRIHPIGGIASIDTSFVYSTVKNTSVFPRLG

Specific function: Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=149, Percent_Identity=35.5704697986577, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=35.6164383561644, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1790182, Length=138, Percent_Identity=28.9855072463768, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17208; Mature: 17208

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKDRQIIRVLQAKGRMTNQDLAEAVNLSPSPCLRRVKNLETAGVIRGYSADVDARAYG
CCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCEEEC
LPITVFVRIKLERHNEEDVRSFERRVQMIDEVLECHILTGATDYQLRVVVADLDAYEDFI
CCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHH
RNRIHPIGGIASIDTSFVYSTVKNTSVFPRLG
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDSKDRQIIRVLQAKGRMTNQDLAEAVNLSPSPCLRRVKNLETAGVIRGYSADVDARAYG
CCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCEEEC
LPITVFVRIKLERHNEEDVRSFERRVQMIDEVLECHILTGATDYQLRVVVADLDAYEDFI
CCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHH
RNRIHPIGGIASIDTSFVYSTVKNTSVFPRLG
HHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]