Click here to switch to the map view.

The map label for this gene is pdtaS [H]

Identifier: 99082564

GI number: 99082564

Start: 2866903

End: 2868744

Strand: Direct

Name: pdtaS [H]

Synonym: TM1040_2724

Alternate gene names: 99082564

Gene position: 2866903-2868744 (Clockwise)

Preceding gene: 99082563

Following gene: 99082566

Centisome position: 89.56

GC content: 57.6

Gene sequence:

>1842_bases
ATGAACTTCCCGTCTCTCGCCCTCTTGAAGGGCGGGGACGCCCGCACGCACGAAACCTCGCTCTCTGAAGATCCGACCGC
GCAGAACCGCGCGGCAGGCTGGACACGCAGCCTGTCCCTGCGCCTTGCGGTCATGCTTTCGATTGCCATGGTGCCACTGG
GTCTGATCGCGGTTGATCAAACCGTCCGGCTGCAAAAAGAGGTCAACACCTCCAACAACCTCAGCCTTCAGGCGCTCACT
GCGGAATTTGCACAAGAAGAGCGCGAGATCATTAAATCCGCCTTCGCATCGGCAGAAACCCTGACGCTTTCGGTGCCCGA
AATCGCACATGACCTGTCGCGATGCAGCTCTTTGATGCGGCGCTTCATCTCCACCACCGATGCGCGCTACAGCTTTGCAG
GGTTCCTGCCCCAGGACGGGGTTATGGCCTGCGCGTCAAGCGGCGGAACAATCGACTACTCCGAAAACCCCGATTTTCCA
GATTGGATGCGCCGTCCAAAGCGCGAAATACGGGTGAATTCTTATGGGCCCGTGGCTGGCTCTGCGGTGCTGATCATATC
CGAACCCGTTTTTGCCAGCACGGGCGTATTTCTCGGCAACCAGATCATTCATGTTCCACATGATCGCATCGACCAACAGT
TCCAGACCAAGCTTGGGGATCGCCCTCTGGATCTTGTCACCGTCAGCGCAGAGGGAGAGATCCTGAGCGCATCCGGTGCG
CGCGAAACAGCCCTAGAGCGGCTCCCGATTGATCTGACTCTCTCAGAGCTGATCTCGATACATGACGGCCAGATCGAAGC
CAAAAACGCAGCGGGCGAGGTCAGGCTGTTCTCGATTGTTCCGATCCTCAGCGATACCTTTTATGTGATCGGCAGCTGGG
ATCCCGAAGGGATCAGCCTGGCGCAAGAGACCAGCGCGCTGCGCTATCTTTTTTTGACACCTGCGCTCTTTCCCATCCTG
ATGTGGCTCGTCAGCCTGGTGCTGATCTATGTGGCGCTGGATCATCAGGTTGTGCGGCACCTGCGCGTGATCGGATTGCA
GATGCGCCAATTTGCAAGTTCCCGTGTACTGCCCGATGTGCAGACCAACGGGTTGATGCCGCATGAATTGGAAGTGATCC
AGAACCAGTTTACCTATGTGGCCGAAAAACTGCTTCATGATGAAGCGCATCTGTTTGACGCGATGCACGACAAGGATGTG
CTGCTGAAGGAGTTGCACCACCGGGTCAAAAACAATCTTCAGCTGATCTCTTCCATCATCTCGATGCAGATGCGCCGCAC
GCGCAATCAGGTGACAGCGGCGGCGCTCAAGACCGTGAACCAGCGTGTCACAAGCATGGCGACGGTGCATCAGACGCTCT
ATCAGGCATCGGAACTCGGTCAGGTCCAAGCCAACGATCTTCTGCGCGATGTGGTGCGCCCGCTGACGGAGCTGGCACCT
ACCACCGCACCGGTGCCCAAGATCGACATCACCTTGGACCCTGTGGTGCTCTATCCGGATCAGGCGGTTCCTCTGGCGCT
CTTGACGGTGGAGGCTGCAACCAATGCGTTGAAATATCTCGGCGTCGACAAGGCCGGAAATCGATGGGTCCGCGTGTCTC
TGACGACAATCGAGGACGGACGGGTCTGCCTGATGATCTCCAATTCCACCAATGATGAGACCGATTTCGAAGATGAGGGC
ACGGGGCTTGGCAGCCAATTGATCCGAGGCTTTGCACGCCAGCTCGAATGCAGCCCCGAGATCACCGAGGGTGAAGACAG
CTACGCCATCAGCGTGACCTTCGACACCTTGCCGTTTGACTCCGAAGATACGGGCAAGACCGGCATTGAGGACGAGGACT
GA

Upstream 100 bases:

>100_bases
CAGCCAAGATGCAGTTGGATGCGAATGAGCAGTTGGAACTGACCGATGCTGCCACCCACGCGGTTGTTGCAGCCAACAAT
GGGACTGCCGCGTGAACCGA

Downstream 100 bases:

>100_bases
CAGCTGTCTCGCACCTTGGTCGCGCGCGATCATCGCTGATTTGCCAAGATCGGTCCTGCCCCGGCTGGGGCGGGCGTCTT
GGCGCGTGTGGACTCTGGTC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MNFPSLALLKGGDARTHETSLSEDPTAQNRAAGWTRSLSLRLAVMLSIAMVPLGLIAVDQTVRLQKEVNTSNNLSLQALT
AEFAQEEREIIKSAFASAETLTLSVPEIAHDLSRCSSLMRRFISTTDARYSFAGFLPQDGVMACASSGGTIDYSENPDFP
DWMRRPKREIRVNSYGPVAGSAVLIISEPVFASTGVFLGNQIIHVPHDRIDQQFQTKLGDRPLDLVTVSAEGEILSASGA
RETALERLPIDLTLSELISIHDGQIEAKNAAGEVRLFSIVPILSDTFYVIGSWDPEGISLAQETSALRYLFLTPALFPIL
MWLVSLVLIYVALDHQVVRHLRVIGLQMRQFASSRVLPDVQTNGLMPHELEVIQNQFTYVAEKLLHDEAHLFDAMHDKDV
LLKELHHRVKNNLQLISSIISMQMRRTRNQVTAAALKTVNQRVTSMATVHQTLYQASELGQVQANDLLRDVVRPLTELAP
TTAPVPKIDITLDPVVLYPDQAVPLALLTVEAATNALKYLGVDKAGNRWVRVSLTTIEDGRVCLMISNSTNDETDFEDEG
TGLGSQLIRGFARQLECSPEITEGEDSYAISVTFDTLPFDSEDTGKTGIEDED

Sequences:

>Translated_613_residues
MNFPSLALLKGGDARTHETSLSEDPTAQNRAAGWTRSLSLRLAVMLSIAMVPLGLIAVDQTVRLQKEVNTSNNLSLQALT
AEFAQEEREIIKSAFASAETLTLSVPEIAHDLSRCSSLMRRFISTTDARYSFAGFLPQDGVMACASSGGTIDYSENPDFP
DWMRRPKREIRVNSYGPVAGSAVLIISEPVFASTGVFLGNQIIHVPHDRIDQQFQTKLGDRPLDLVTVSAEGEILSASGA
RETALERLPIDLTLSELISIHDGQIEAKNAAGEVRLFSIVPILSDTFYVIGSWDPEGISLAQETSALRYLFLTPALFPIL
MWLVSLVLIYVALDHQVVRHLRVIGLQMRQFASSRVLPDVQTNGLMPHELEVIQNQFTYVAEKLLHDEAHLFDAMHDKDV
LLKELHHRVKNNLQLISSIISMQMRRTRNQVTAAALKTVNQRVTSMATVHQTLYQASELGQVQANDLLRDVVRPLTELAP
TTAPVPKIDITLDPVVLYPDQAVPLALLTVEAATNALKYLGVDKAGNRWVRVSLTTIEDGRVCLMISNSTNDETDFEDEG
TGLGSQLIRGFARQLECSPEITEGEDSYAISVTFDTLPFDSEDTGKTGIEDED
>Mature_613_residues
MNFPSLALLKGGDARTHETSLSEDPTAQNRAAGWTRSLSLRLAVMLSIAMVPLGLIAVDQTVRLQKEVNTSNNLSLQALT
AEFAQEEREIIKSAFASAETLTLSVPEIAHDLSRCSSLMRRFISTTDARYSFAGFLPQDGVMACASSGGTIDYSENPDFP
DWMRRPKREIRVNSYGPVAGSAVLIISEPVFASTGVFLGNQIIHVPHDRIDQQFQTKLGDRPLDLVTVSAEGEILSASGA
RETALERLPIDLTLSELISIHDGQIEAKNAAGEVRLFSIVPILSDTFYVIGSWDPEGISLAQETSALRYLFLTPALFPIL
MWLVSLVLIYVALDHQVVRHLRVIGLQMRQFASSRVLPDVQTNGLMPHELEVIQNQFTYVAEKLLHDEAHLFDAMHDKDV
LLKELHHRVKNNLQLISSIISMQMRRTRNQVTAAALKTVNQRVTSMATVHQTLYQASELGQVQANDLLRDVVRPLTELAP
TTAPVPKIDITLDPVVLYPDQAVPLALLTVEAATNALKYLGVDKAGNRWVRVSLTTIEDGRVCLMISNSTNDETDFEDEG
TGLGSQLIRGFARQLECSPEITEGEDSYAISVTFDTLPFDSEDTGKTGIEDED

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67562; Mature: 67562

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPSLALLKGGDARTHETSLSEDPTAQNRAAGWTRSLSLRLAVMLSIAMVPLGLIAVDQ
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
TVRLQKEVNTSNNLSLQALTAEFAQEEREIIKSAFASAETLTLSVPEIAHDLSRCSSLMR
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
RFISTTDARYSFAGFLPQDGVMACASSGGTIDYSENPDFPDWMRRPKREIRVNSYGPVAG
HHHHCCCCCEEEECCCCCCCHHHEECCCCEEECCCCCCCHHHHHCCHHHEEECCCCCCCC
SAVLIISEPVFASTGVFLGNQIIHVPHDRIDQQFQTKLGDRPLDLVTVSAEGEILSASGA
CEEEEEECCCHHHCCHHHCCEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCC
RETALERLPIDLTLSELISIHDGQIEAKNAAGEVRLFSIVPILSDTFYVIGSWDPEGISL
HHHHHHHCCCCEEHHHHHHHCCCCEEECCCCCCEEEEEEEHHHCCCEEEEECCCCCCCCH
AQETSALRYLFLTPALFPILMWLVSLVLIYVALDHQVVRHLRVIGLQMRQFASSRVLPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QTNGLMPHELEVIQNQFTYVAEKLLHDEAHLFDAMHDKDVLLKELHHRVKNNLQLISSII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SMQMRRTRNQVTAAALKTVNQRVTSMATVHQTLYQASELGQVQANDLLRDVVRPLTELAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
TTAPVPKIDITLDPVVLYPDQAVPLALLTVEAATNALKYLGVDKAGNRWVRVSLTTIEDG
CCCCCCEEEEEECCEEECCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEEEEEEECCC
RVCLMISNSTNDETDFEDEGTGLGSQLIRGFARQLECSPEITEGEDSYAISVTFDTLPFD
CEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCC
SEDTGKTGIEDED
CCCCCCCCCCCCC
>Mature Secondary Structure
MNFPSLALLKGGDARTHETSLSEDPTAQNRAAGWTRSLSLRLAVMLSIAMVPLGLIAVDQ
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
TVRLQKEVNTSNNLSLQALTAEFAQEEREIIKSAFASAETLTLSVPEIAHDLSRCSSLMR
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
RFISTTDARYSFAGFLPQDGVMACASSGGTIDYSENPDFPDWMRRPKREIRVNSYGPVAG
HHHHCCCCCEEEECCCCCCCHHHEECCCCEEECCCCCCCHHHHHCCHHHEEECCCCCCCC
SAVLIISEPVFASTGVFLGNQIIHVPHDRIDQQFQTKLGDRPLDLVTVSAEGEILSASGA
CEEEEEECCCHHHCCHHHCCEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCC
RETALERLPIDLTLSELISIHDGQIEAKNAAGEVRLFSIVPILSDTFYVIGSWDPEGISL
HHHHHHHCCCCEEHHHHHHHCCCCEEECCCCCCEEEEEEEHHHCCCEEEEECCCCCCCCH
AQETSALRYLFLTPALFPILMWLVSLVLIYVALDHQVVRHLRVIGLQMRQFASSRVLPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QTNGLMPHELEVIQNQFTYVAEKLLHDEAHLFDAMHDKDVLLKELHHRVKNNLQLISSII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SMQMRRTRNQVTAAALKTVNQRVTSMATVHQTLYQASELGQVQANDLLRDVVRPLTELAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
TTAPVPKIDITLDPVVLYPDQAVPLALLTVEAATNALKYLGVDKAGNRWVRVSLTTIEDG
CCCCCCEEEEEECCEEECCCCCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEEEEEEECCC
RVCLMISNSTNDETDFEDEGTGLGSQLIRGFARQLECSPEITEGEDSYAISVTFDTLPFD
CEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCC
SEDTGKTGIEDED
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]