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The map label for this gene is fnrL [H]

Identifier: 99082387

GI number: 99082387

Start: 2688724

End: 2689464

Strand: Reverse

Name: fnrL [H]

Synonym: TM1040_2547

Alternate gene names: 99082387

Gene position: 2689464-2688724 (Counterclockwise)

Preceding gene: 99082389

Following gene: 99082385

Centisome position: 84.02

GC content: 58.43

Gene sequence:

>741_bases
ATGTCCCTTGCTCAATTTCAGTCCGTCGAATGTGCGGATTGTCCGATCCGCCATCGCGCGGTCTGCGCCCGTTGCGATGC
CGATGAGCTTGAGGCGCTCGATGCGATCAAGTTTTATCGCAGCTATGAGGCCGGGCAAACTGTGGTGTGGTCCGGGGACC
AGATGAATTTTGTGGGCTCCGTTGTCTCGGGTATCGCGACCTTGACCCAAACCATGGAAGACGGGCGCACCCAGATGGTC
GGTCTGCTGTTGCCGAGCGATTTTGTGGGGCGGCCCGGGCGGGAGGGATCCGCCTATGACGTTGTGGCCACCACAGACGT
GATAATGTGTTGTTTCAGAAAGAAACCTTTCGAAGACCTAATGGTGCGCACACCGCATATCGCGCATCGTTTGCTGGAAA
TGACGCTCGACGAGCTTGATGCTGCGCGCGAGTGGATGCTGGTCTTGGGCCGCAAGACCGCACGCGAAAAGATCGCCAGC
CTTCTGTCGATCATCGCGCGTCGCGATGCATCGTTGGCGGTGGATCCTTCGAACGGAGCTGTCAGCTTTGATTTGAAACT
CACCCGCGAGGCGATGGCGGACTATCTCGGCTTGACGCTCGAAACCGTAAGCCGCCAGATTTCTGCGTTGAAAAAGGCGG
GTGTGATCCAGCTGGAAGGCAAGCGTCATGTGACGGTCCCAGACATGCATCGCCTGATCGAAGAGGCGGGCGATGACAGC
GACGGTGGCGTTCTGGGCTAG

Upstream 100 bases:

>100_bases
CGAAAAGTCCGAGCCGCGCCAATTGAGATTCCTGTGTCATGCGACTAGGGTAGGGTCAGCTGGCACCGTCGGCTTTGACA
CAGATCAACCAGAGGCACAC

Downstream 100 bases:

>100_bases
AGGCAGCGTTGATGTGTAGATGTCCGTTGACCGCATCCGCTCACTCACGAAGTCCCCATAGTGACATCGAAAGGCGCTCT
TGCAAAAGTTGTGCCTGCGC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSLAQFQSVECADCPIRHRAVCARCDADELEALDAIKFYRSYEAGQTVVWSGDQMNFVGSVVSGIATLTQTMEDGRTQMV
GLLLPSDFVGRPGREGSAYDVVATTDVIMCCFRKKPFEDLMVRTPHIAHRLLEMTLDELDAAREWMLVLGRKTAREKIAS
LLSIIARRDASLAVDPSNGAVSFDLKLTREAMADYLGLTLETVSRQISALKKAGVIQLEGKRHVTVPDMHRLIEEAGDDS
DGGVLG

Sequences:

>Translated_246_residues
MSLAQFQSVECADCPIRHRAVCARCDADELEALDAIKFYRSYEAGQTVVWSGDQMNFVGSVVSGIATLTQTMEDGRTQMV
GLLLPSDFVGRPGREGSAYDVVATTDVIMCCFRKKPFEDLMVRTPHIAHRLLEMTLDELDAAREWMLVLGRKTAREKIAS
LLSIIARRDASLAVDPSNGAVSFDLKLTREAMADYLGLTLETVSRQISALKKAGVIQLEGKRHVTVPDMHRLIEEAGDDS
DGGVLG
>Mature_245_residues
SLAQFQSVECADCPIRHRAVCARCDADELEALDAIKFYRSYEAGQTVVWSGDQMNFVGSVVSGIATLTQTMEDGRTQMVG
LLLPSDFVGRPGREGSAYDVVATTDVIMCCFRKKPFEDLMVRTPHIAHRLLEMTLDELDAAREWMLVLGRKTAREKIASL
LSIIARRDASLAVDPSNGAVSFDLKLTREAMADYLGLTLETVSRQISALKKAGVIQLEGKRHVTVPDMHRLIEEAGDDSD
GGVLG

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=238, Percent_Identity=28.1512605042017, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26993; Mature: 26862

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAQFQSVECADCPIRHRAVCARCDADELEALDAIKFYRSYEAGQTVVWSGDQMNFVGS
CCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHH
VVSGIATLTQTMEDGRTQMVGLLLPSDFVGRPGREGSAYDVVATTDVIMCCFRKKPFEDL
HHHHHHHHHHHHHCCHHEEEEEECCCHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHH
MVRTPHIAHRLLEMTLDELDAAREWMLVLGRKTAREKIASLLSIIARRDASLAVDPSNGA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCE
VSFDLKLTREAMADYLGLTLETVSRQISALKKAGVIQLEGKRHVTVPDMHRLIEEAGDDS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHCCCCC
DGGVLG
CCCCCC
>Mature Secondary Structure 
SLAQFQSVECADCPIRHRAVCARCDADELEALDAIKFYRSYEAGQTVVWSGDQMNFVGS
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHH
VVSGIATLTQTMEDGRTQMVGLLLPSDFVGRPGREGSAYDVVATTDVIMCCFRKKPFEDL
HHHHHHHHHHHHHCCHHEEEEEECCCHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHH
MVRTPHIAHRLLEMTLDELDAAREWMLVLGRKTAREKIASLLSIIARRDASLAVDPSNGA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCE
VSFDLKLTREAMADYLGLTLETVSRQISALKKAGVIQLEGKRHVTVPDMHRLIEEAGDDS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHCCCCC
DGGVLG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]