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The map label for this gene is yrbG [C]

Identifier: 99082362

GI number: 99082362

Start: 2662400

End: 2663344

Strand: Reverse

Name: yrbG [C]

Synonym: TM1040_2522

Alternate gene names: 99082362

Gene position: 2663344-2662400 (Counterclockwise)

Preceding gene: 99082363

Following gene: 99082361

Centisome position: 83.21

GC content: 57.99

Gene sequence:

>945_bases
ATGATGCCCTGGCTGCTTTCTGTCCTAGGCTTGGTAATTCTGTTGCTGGCAGGTGATGCGCTGGTGCGCGGCGCGGTGAA
CCTCAGTCTGCGGGTTGGTATTCCTGCGTTGATCGTCAGCCTGACCATCGTGGCATTTGGCACCTCTGCGCCAGAGCTGC
TGATCGCGATCCAGGCGGTGCATGAAAATGCCGACGGTATCGCACTGGGTAACGTGGTGGGGTCCAATACGGCCAACATA
CTTTTGGTGCTCGGGCTGCCCGCCTTGATGCGTGCACTGCACACAAGCGAGTGCAACACGCGCAAGAACTACATCTTCAT
GATTGCGGCCTCGGTGCTGTTTATCGCGCTGGCCTTTGTTGGGACCTTCACTTGGGTCTCGGGCGTTGTCCTTCTGCTGG
CGCTCTTTGGCGTACTGTTTACGGCTTTTCGCGAGGCTCAGGCGCATCGTGCTGCCGGGGAAGACGACGAACTCGAAGAG
ATTGACGAAGCCGACCCGGACATGCCGTATTGGCGCATCGGCATATATCTGGTGCTCGGTTTGATCGGTTTGCCTCTTGG
TGCAGAGCTTTTGGTCGAGAACGCGACCATCATCGCGCGCATGTATGGGCTCTCTGAAACCGTGATCGGCCTGACGTTGG
TGGCGCTGGGCACCTCGCTGCCTGAGCTGGCCACAACGCTGGTTGCGGCCCTGCGCCGACAGGCGGACGTTGCCTTGGGC
AATGTGATCGGCTCAAACATGTTCAACCTTCTGGCAATCATCGGTCTGACCACTTTTGTGGGGCCGATCACCGTCGACCC
GGCCTTCCTGCGCTTTGATCTCTGGGTGATGCTGGCGTCGTCCTTGCTGATCATCCCGTTTGTGTTCTTCCGACAGGACA
TTACGCGCATCTGGGGGATCATATTGACGGGGCTTTATGTGGTCTATGTATGGTCTCTGCTCTAG

Upstream 100 bases:

>100_bases
TTCCGGGACAAAAGAAACTCAATTCGGCTCGCTGCCCGTCCTGTGGACGTTTCAAAATCGGCAGGGGCGCCTGTGACTGT
GGACGAGGAGGTCCAAAACC

Downstream 100 bases:

>100_bases
GTCTTTGTGAAAGCCACAAAGACAAAGGGATCAAACATGCGGGCATTGGTAACCGGAGCGGGTAAGCGTTTGGGGCGGGC
AATGGCCTTGGCGCTTGCAG

Product: K+-dependent Na+/Ca+ exchanger related-protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MMPWLLSVLGLVILLLAGDALVRGAVNLSLRVGIPALIVSLTIVAFGTSAPELLIAIQAVHENADGIALGNVVGSNTANI
LLVLGLPALMRALHTSECNTRKNYIFMIAASVLFIALAFVGTFTWVSGVVLLLALFGVLFTAFREAQAHRAAGEDDELEE
IDEADPDMPYWRIGIYLVLGLIGLPLGAELLVENATIIARMYGLSETVIGLTLVALGTSLPELATTLVAALRRQADVALG
NVIGSNMFNLLAIIGLTTFVGPITVDPAFLRFDLWVMLASSLLIIPFVFFRQDITRIWGIILTGLYVVYVWSLL

Sequences:

>Translated_314_residues
MMPWLLSVLGLVILLLAGDALVRGAVNLSLRVGIPALIVSLTIVAFGTSAPELLIAIQAVHENADGIALGNVVGSNTANI
LLVLGLPALMRALHTSECNTRKNYIFMIAASVLFIALAFVGTFTWVSGVVLLLALFGVLFTAFREAQAHRAAGEDDELEE
IDEADPDMPYWRIGIYLVLGLIGLPLGAELLVENATIIARMYGLSETVIGLTLVALGTSLPELATTLVAALRRQADVALG
NVIGSNMFNLLAIIGLTTFVGPITVDPAFLRFDLWVMLASSLLIIPFVFFRQDITRIWGIILTGLYVVYVWSLL
>Mature_314_residues
MMPWLLSVLGLVILLLAGDALVRGAVNLSLRVGIPALIVSLTIVAFGTSAPELLIAIQAVHENADGIALGNVVGSNTANI
LLVLGLPALMRALHTSECNTRKNYIFMIAASVLFIALAFVGTFTWVSGVVLLLALFGVLFTAFREAQAHRAAGEDDELEE
IDEADPDMPYWRIGIYLVLGLIGLPLGAELLVENATIIARMYGLSETVIGLTLVALGTSLPELATTLVAALRRQADVALG
NVIGSNMFNLLAIIGLTTFVGPITVDPAFLRFDLWVMLASSLLIIPFVFFRQDITRIWGIILTGLYVVYVWSLL

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=296, Percent_Identity=34.4594594594595, Blast_Score=127, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 33700; Mature: 33700

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPWLLSVLGLVILLLAGDALVRGAVNLSLRVGIPALIVSLTIVAFGTSAPELLIAIQAV
CCHHHHHHHHHHHHHHHCHHHHHHHHCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHH
HENADGIALGNVVGSNTANILLVLGLPALMRALHTSECNTRKNYIFMIAASVLFIALAFV
HCCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
GTFTWVSGVVLLLALFGVLFTAFREAQAHRAAGEDDELEEIDEADPDMPYWRIGIYLVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
LIGLPLGAELLVENATIIARMYGLSETVIGLTLVALGTSLPELATTLVAALRRQADVALG
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
NVIGSNMFNLLAIIGLTTFVGPITVDPAFLRFDLWVMLASSLLIIPFVFFRQDITRIWGI
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTGLYVVYVWSLL
HHHHHHHHHHHHHC
>Mature Secondary Structure
MMPWLLSVLGLVILLLAGDALVRGAVNLSLRVGIPALIVSLTIVAFGTSAPELLIAIQAV
CCHHHHHHHHHHHHHHHCHHHHHHHHCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHH
HENADGIALGNVVGSNTANILLVLGLPALMRALHTSECNTRKNYIFMIAASVLFIALAFV
HCCCCCEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
GTFTWVSGVVLLLALFGVLFTAFREAQAHRAAGEDDELEEIDEADPDMPYWRIGIYLVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
LIGLPLGAELLVENATIIARMYGLSETVIGLTLVALGTSLPELATTLVAALRRQADVALG
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
NVIGSNMFNLLAIIGLTTFVGPITVDPAFLRFDLWVMLASSLLIIPFVFFRQDITRIWGI
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTGLYVVYVWSLL
HHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]