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The map label for this gene is prtE [H]

Identifier: 99082318

GI number: 99082318

Start: 2616801

End: 2618123

Strand: Reverse

Name: prtE [H]

Synonym: TM1040_2478

Alternate gene names: 99082318

Gene position: 2618123-2616801 (Counterclockwise)

Preceding gene: 99082319

Following gene: 99082317

Centisome position: 81.79

GC content: 61.15

Gene sequence:

>1323_bases
ATGATCGACCCAATGACTGAGACAGCGCACAAAAGCTGGTCCGTACGCGGAGCCCTGATCGCGGGCGCGTTGGGTGTGAT
CATTCTGCTTGGCGGCTTTGGTACCTGGGCGGTTTTTTCCAATATCGCCGGGGCGGTTGTCGCCTCTGGCCAGATCGAAG
TGGATCGCAATCGTCAGGTTGTGCAGCACATCGATGGCGGAGTCGTGGAAGACATTCTTGTGGACGAAGGCGATCTGGTC
ACCGCTGGCCAGACCTTGGTTCGTCTTGACGCGGTGGACCTGCGCTCGCAGCTTACGATTACCGAAGGACAGTTGTTTGA
GATGATGGCCCGCCGAGGCAGGCTCGAGGCCGAGCGCGATGAGGTGGACACCATCAGCTTTGATGCAGAACTCCTGACGC
TGGCGCAGCAACGCCCCGAAGTGGCTGAACTCGTCGAAGGGCAAGCCCGCCTGTTTCGCGCCCGACGCGAGTCGGTGCGC
CGCGAGGTGGAGCAACTTGAAAAGCGCGCGGTCCAGATCGAGGATCAGATCACTGGCGTGCGCGCCCAGCAGGAGGCCAC
ACGAGAACAGCTGGTTCTGATCAAAGAAGAGCTCAGCAACCAGCAGTCCCTGCTGGATCGAGGTCTTGCGCAGGCGTCGG
TGGTGCTGAACCTCCGGCGCAATCAGGCCAACCTGCAAGGGACGCTGGGCGAGTTGATTGCGAGTGAGGCGCAGGCACGC
GGTCGCATCACCGAGATCGAAATCGAGGCGCTGAAGCTCCGTAATCAGCGCCGCGAGGAGGCCATCACCCGCCTGCGCGA
CCTGCGCTACAGAGAGCTCGAGTTGATTGAAACGCGCCGTTCTCTGATTGATCGACTGGGCCGTCTGGACATTACCGCGC
CTGTTTCGGGCGTGGTCTATGGGATGAGTGTGCGCACCCCACGTTCCGTCATCCGGCCCGCCGACCCTGTACTCTATCTG
GTGCCGCAGGACCGACCCCTGGTGATCGCTGCGCGGGTTGCGCCGACGGATATTGACCAGATCCATGTCGGCCAGGCGGT
CTCGATCAGATTGCCCGCGCTGGATCAGCGCCAAACGCCGGAGCTGTTTGGATCGGTGACGCTGTTTTCGGCGGATGCTT
TCCAGGACGAAACCACCGGGGCCTCCTACTATCGCGCCGAGATCGAGTTGAATGCGGGCGAAATGGATCGGCTCCCGGAG
GGCACGGTTCTCATCCCGGGGATGCCGGTCGAAAGCTTTATCCGCACTGCTGATCGCTCGCCATTGGCCTATCTTGTAAA
ACCACTTTCGGACTATTTCGTACGCGCGTTCCGCGAAAGTTGA

Upstream 100 bases:

>100_bases
ATGAGGTGCTGCGGAAAATGGTTGCAAATCACCGCGAACTGCAACCCTCTGGTGCGCGCCGCCCGGCTCAGGGAGCAAAT
GCGCTGAAGGGAGGCCCTCG

Downstream 100 bases:

>100_bases
GGAACGCGTAGAAACCTGTCCAAAGGGGTCGCATTTGCCTCTTTTCCCGCTGAGGCTTCCACTGTAGCGTCCGGCGAAAT
GACACACGGACGTTGATACA

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIDPMTETAHKSWSVRGALIAGALGVIILLGGFGTWAVFSNIAGAVVASGQIEVDRNRQVVQHIDGGVVEDILVDEGDLV
TAGQTLVRLDAVDLRSQLTITEGQLFEMMARRGRLEAERDEVDTISFDAELLTLAQQRPEVAELVEGQARLFRARRESVR
REVEQLEKRAVQIEDQITGVRAQQEATREQLVLIKEELSNQQSLLDRGLAQASVVLNLRRNQANLQGTLGELIASEAQAR
GRITEIEIEALKLRNQRREEAITRLRDLRYRELELIETRRSLIDRLGRLDITAPVSGVVYGMSVRTPRSVIRPADPVLYL
VPQDRPLVIAARVAPTDIDQIHVGQAVSIRLPALDQRQTPELFGSVTLFSADAFQDETTGASYYRAEIELNAGEMDRLPE
GTVLIPGMPVESFIRTADRSPLAYLVKPLSDYFVRAFRES

Sequences:

>Translated_440_residues
MIDPMTETAHKSWSVRGALIAGALGVIILLGGFGTWAVFSNIAGAVVASGQIEVDRNRQVVQHIDGGVVEDILVDEGDLV
TAGQTLVRLDAVDLRSQLTITEGQLFEMMARRGRLEAERDEVDTISFDAELLTLAQQRPEVAELVEGQARLFRARRESVR
REVEQLEKRAVQIEDQITGVRAQQEATREQLVLIKEELSNQQSLLDRGLAQASVVLNLRRNQANLQGTLGELIASEAQAR
GRITEIEIEALKLRNQRREEAITRLRDLRYRELELIETRRSLIDRLGRLDITAPVSGVVYGMSVRTPRSVIRPADPVLYL
VPQDRPLVIAARVAPTDIDQIHVGQAVSIRLPALDQRQTPELFGSVTLFSADAFQDETTGASYYRAEIELNAGEMDRLPE
GTVLIPGMPVESFIRTADRSPLAYLVKPLSDYFVRAFRES
>Mature_440_residues
MIDPMTETAHKSWSVRGALIAGALGVIILLGGFGTWAVFSNIAGAVVASGQIEVDRNRQVVQHIDGGVVEDILVDEGDLV
TAGQTLVRLDAVDLRSQLTITEGQLFEMMARRGRLEAERDEVDTISFDAELLTLAQQRPEVAELVEGQARLFRARRESVR
REVEQLEKRAVQIEDQITGVRAQQEATREQLVLIKEELSNQQSLLDRGLAQASVVLNLRRNQANLQGTLGELIASEAQAR
GRITEIEIEALKLRNQRREEAITRLRDLRYRELELIETRRSLIDRLGRLDITAPVSGVVYGMSVRTPRSVIRPADPVLYL
VPQDRPLVIAARVAPTDIDQIHVGQAVSIRLPALDQRQTPELFGSVTLFSADAFQDETTGASYYRAEIELNAGEMDRLPE
GTVLIPGMPVESFIRTADRSPLAYLVKPLSDYFVRAFRES

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48990; Mature: 48990

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDPMTETAHKSWSVRGALIAGALGVIILLGGFGTWAVFSNIAGAVVASGQIEVDRNRQV
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCEEEECCCHHH
VQHIDGGVVEDILVDEGDLVTAGQTLVRLDAVDLRSQLTITEGQLFEMMARRGRLEAERD
HHHCCCCHHHHHHCCCCCEEECCCCEEEEEHHHHHCCEEECHHHHHHHHHHCCCCCCCCC
EVDTISFDAELLTLAQQRPEVAELVEGQARLFRARRESVRREVEQLEKRAVQIEDQITGV
CCCEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RAQQEATREQLVLIKEELSNQQSLLDRGLAQASVVLNLRRNQANLQGTLGELIASEAQAR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHC
GRITEIEIEALKLRNQRREEAITRLRDLRYRELELIETRRSLIDRLGRLDITAPVSGVVY
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEE
GMSVRTPRSVIRPADPVLYLVPQDRPLVIAARVAPTDIDQIHVGQAVSIRLPALDQRQTP
EEECCCCHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCEECCCEEEEECCCCCCCCCH
ELFGSVTLFSADAFQDETTGASYYRAEIELNAGEMDRLPEGTVLIPGMPVESFIRTADRS
HHHCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCHHHHHHHCCCC
PLAYLVKPLSDYFVRAFRES
CHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDPMTETAHKSWSVRGALIAGALGVIILLGGFGTWAVFSNIAGAVVASGQIEVDRNRQV
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCEEEECCCHHH
VQHIDGGVVEDILVDEGDLVTAGQTLVRLDAVDLRSQLTITEGQLFEMMARRGRLEAERD
HHHCCCCHHHHHHCCCCCEEECCCCEEEEEHHHHHCCEEECHHHHHHHHHHCCCCCCCCC
EVDTISFDAELLTLAQQRPEVAELVEGQARLFRARRESVRREVEQLEKRAVQIEDQITGV
CCCEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RAQQEATREQLVLIKEELSNQQSLLDRGLAQASVVLNLRRNQANLQGTLGELIASEAQAR
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHC
GRITEIEIEALKLRNQRREEAITRLRDLRYRELELIETRRSLIDRLGRLDITAPVSGVVY
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEE
GMSVRTPRSVIRPADPVLYLVPQDRPLVIAARVAPTDIDQIHVGQAVSIRLPALDQRQTP
EEECCCCHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCEECCCEEEEECCCCCCCCCH
ELFGSVTLFSADAFQDETTGASYYRAEIELNAGEMDRLPEGTVLIPGMPVESFIRTADRS
HHHCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCHHHHHHHCCCC
PLAYLVKPLSDYFVRAFRES
CHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]