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The map label for this gene is phhB

Identifier: 99082314

GI number: 99082314

Start: 2613915

End: 2614211

Strand: Reverse

Name: phhB

Synonym: TM1040_2474

Alternate gene names: NA

Gene position: 2614211-2613915 (Counterclockwise)

Preceding gene: 99082315

Following gene: 99082311

Centisome position: 81.67

GC content: 52.86

Gene sequence:

>297_bases
ATGACCGAGAAGCTTTCCGATGAAACCCGAGGCCCCCTGCTGGAGCCATTATTCGCTACGGGATGGGAACTTGAAACAGG
ACGAGATGCGATTCGAAAAACCTATGAGTTTGCGGACTTTGTGGAGGCCTTTGCCTTCATGACAAAGGCCGCGATCTGGG
CGGAAAAATGGAATCACCATCCAGAATGGAGCAATATCTACAACAAAGTGACGGTTGTTCTGACCACCCATGACGTCGGC
GGGGTGAGCTCCCTCGATGCAAAGCTCGCCCGAAAGATGGATGGTCTGACCTCCTAG

Upstream 100 bases:

>100_bases
TCGAACAATATCTGGAGGCAGAACGGGCTGCCGTAGGAGAAGAGATCGAGATCCTCACCTCCTATGGGCCGTTCAAGAAG
ACCCATGTGGAGGAACAGGA

Downstream 100 bases:

>100_bases
CTCTTGCAGAGAGCGGTAAGGACACAACAGGTGCGCCAGATCGGAAGGCGCTAGGCAGCCAGCGCGCAGTCTCATCGCGT
TCTTCAGGTCAGAGACGGTG

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MTEKLSDETRGPLLEPLFATGWELETGRDAIRKTYEFADFVEAFAFMTKAAIWAEKWNHHPEWSNIYNKVTVVLTTHDVG
GVSSLDAKLARKMDGLTS

Sequences:

>Translated_98_residues
MTEKLSDETRGPLLEPLFATGWELETGRDAIRKTYEFADFVEAFAFMTKAAIWAEKWNHHPEWSNIYNKVTVVLTTHDVG
GVSSLDAKLARKMDGLTS
>Mature_97_residues
TEKLSDETRGPLLEPLFATGWELETGRDAIRKTYEFADFVEAFAFMTKAAIWAEKWNHHPEWSNIYNKVTVVLTTHDVGG
VSSLDAKLARKMDGLTS

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=87, Percent_Identity=52.8735632183908, Blast_Score=97, Evalue=2e-21,
Organism=Homo sapiens, GI134133240, Length=90, Percent_Identity=47.7777777777778, Blast_Score=96, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI115533705, Length=86, Percent_Identity=53.4883720930233, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45549100, Length=94, Percent_Identity=52.1276595744681, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_SILST (Q1GDR0)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_614468.1
- ProteinModelPortal:   Q1GDR0
- SMR:   Q1GDR0
- STRING:   Q1GDR0
- GeneID:   4076839
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_2474
- NMPDR:   fig|292414.1.peg.807
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   SEERKTR
- ProtClustDB:   PRK00823
- BioCyc:   SSP292414:TM1040_2474-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11091; Mature: 10959

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKLSDETRGPLLEPLFATGWELETGRDAIRKTYEFADFVEAFAFMTKAAIWAEKWNHH
CCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEWSNIYNKVTVVLTTHDVGGVSSLDAKLARKMDGLTS
CCHHHHHCEEEEEEEECCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEKLSDETRGPLLEPLFATGWELETGRDAIRKTYEFADFVEAFAFMTKAAIWAEKWNHH
CCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEWSNIYNKVTVVLTTHDVGGVSSLDAKLARKMDGLTS
CCHHHHHCEEEEEEEECCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA