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The map label for this gene is mcpA [H]

Identifier: 99082293

GI number: 99082293

Start: 2594208

End: 2596574

Strand: Direct

Name: mcpA [H]

Synonym: TM1040_2453

Alternate gene names: 99082293

Gene position: 2594208-2596574 (Clockwise)

Preceding gene: 99082292

Following gene: 99082295

Centisome position: 81.05

GC content: 58.01

Gene sequence:

>2367_bases
ATGTTTCGCTCAAAAAACATGCGAATTTCTCGCAAGCTGCCGCTGCTGTTTGCAGGCTTTTGCGCGGGAACCAGCTTTCT
TCTCATTGCCGCTTCCTTGATCGCCTTCAACCGCTTTGCAGAACGATCTGTGCAGGACCAAATGGTGTCCCTTCTGGCCG
ATCGAAGCTATTCGGTGCGGCAAATCATCTCCAACATCGAGACTGATCTTGTTTCTTTGTCCCAGTCGCCCGCGACGTCC
TCTGCCCTGGTGGCGTTTGACGAAGGCTGGGAGGCTCTGGGTCCGGATGCACAAGCCGCCCTGCAAACGGCCTACATCAC
TCAAAACCGCCACCCCAGCGGTGCAAAGCACAAGCTTGATCGCGCGGAGGGAGAGGCCGCCTATCACGACGCCCATGAGA
CCTTTCACAATGGCCTGCGAACGCTGATTGAAGTCAAAGGCTATTATGACGCCTTCCTGATCAATCCCGAAGGCGACATT
ATCTATTCGGTCTTCAAGGAGCTGGATTACGCCACCAACCTCAGCGATGGAAAATATGCACAATCCGGCCTTGGTGCTGC
CTATCGCGCGGCCACTAAGGCGGCGGAACGCGAGGTCGTCTTTGCAGATATGGATCCCTATGCGCCCAGCGCGGGCGCGG
CGGCAGCATTTCTGGCAACCCCTGTCAAAGGCTCCGATGGCTCCCTCATCGGTGTGATCGCCGTGCAAGTACCCGTCGAT
ATGCTAGGCGTGATCACCAACAACAGCGATGGGCTTGGCAAAACCGCGCAGGTCTTTCTTGTAGGTGCTGATTTTAAGGC
CCGCACCAAATCCCGTTTCGACGGCGGCTTTGGCGTGCTGGAGACGCTGCCCGAAGTCGACCACATCAAAGAAGCCCTGC
GTGGCGAGACGGGCTTTTCCGTTGGAACAATCGGCCTGGATGGCCACCCAGTATATGCGGCATCGCGCCCCCTGGGCCTC
GAGCTGGCCAATTGGGCTCTGGTGGTCGAGCAAGATGTTTCGGATGTGATGGCTCCTGTGCGCCAAAAAGCGTGGGCCTT
GGTTCTCATCGGGCTCGCGGTCTGCACGATCATGTCATTGATTGGCTGGCGGATCGCAACCTCGATCACGCGCCCCCTGC
ATCAGATCGCAGTGGGGATGGATCGCGTCGCCTCTGGAGATGTGGCCACCACAGTCGAAGAAGCCCAGCGCAGCGATGAA
ATCGGCGACATCGGGAAATCGCTTCTGTCGCTGCAAGAGGACCTGAAAGTCGCGCGCGATGCAGAAGAGCAGCGCATCGA
GCAACAGCGCGAACAGGAGAAGGTTGTCGAAAACCTGAGCGCGGGGCTTTTGCAGCTTTCTCAAGGTGACTTCTCCGCCA
CGATTGATACGCCGTTCTCCGGCGAGCATGAGACGCTGCGCGCGGACTTCAACAAGACCGTCACCACACTGAATGAGACG
CTTGGGCATGTGGTGACTGCGGTGAGCCGCATCCGAAACGGCGCTGCAGAGATCAATCAATCTTCCAACGACCTGTCCCA
TCGCACAGAGAGCCAGGCCGCGACACTTGAAGAAACTGCCGCTGCATTGGAAGAAATGACCGCAAGCGTGAAATCTGCGG
CGGATAGCGCGCGCAGCGTGGAAACCATCACCGGCGAAGCCAAACAGGAGGCAGAAGCCAGTGGCAAAGTGGTGCAAAAC
GCTGTGACCGCGATGACCGAAATCGAAGAATCCTCAAAACAGATCGCGCAGATCATTCTGGTGATCGACGACATCGCCTT
TCAGACAAACCTGTTGGCGCTGAACGCAGGTGTCGAGGCGGCGCGTGCAGGTGAAGCCGGTCGCGGGTTTGCCGTGGTCG
CAAGCGAAGTGCGCGCATTGGCGCAGCGGTCTTCGGACGCCGCGATGGAAATCAAAACGCTGATCGGTGAAAGCTCCAAA
CAAGTGGAATCGGGCGTTGATCTGGTGGGTAAAGCCGGCGAAGCCCTCAACATGATCGTCGAGCGGGTCAATAATATCGC
GCAGCTGGTCTCCGGCATCGCCGAAGGCGCTTCAGAGCAATCCAACGGGATCGAGGAAATCAACACTGGCATGGTGCAGC
TGGATCAGGTCACGCAACAAAACGCCGCGATGGTCGAAGAGGCTTCAGCAGCTTGCCAGATGCTTGACACTGACGCATCC
GAACTGGGTGGCGTTGTGGCCAAGTTCAAACTCTCCGGTCAAACTGCACAAAACACCCCAACCACATCCACGGCTGTGTC
CTCGGCGGCTGCCAGCGACAGTTGGGATCTGGACGCGGAAACGGATGAGACGCCCATGGCGCCTACAGCACATGGGGTCC
CCACCAGCAACGGCAACGCGGCCTATAACTTTTACGAGGACTTCTGA

Upstream 100 bases:

>100_bases
CCGCGACCCAAAAGCATGTGCCGGCCGGTATGTTTGCAAATTTTTAAAGCACGCGCCGAGAAAATCCTGTGAAGGCTCAG
AAAACCCACAGGACACCAAG

Downstream 100 bases:

>100_bases
TCGCGCACCACGCTGGGTCCGAGGTATCCGTCCAGCTGATGGGCACCAGCACTTGCGCCGCTCCATGAGGGGTGCGCCAC
GTCAGCTGCGGCCTGCGGCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MFRSKNMRISRKLPLLFAGFCAGTSFLLIAASLIAFNRFAERSVQDQMVSLLADRSYSVRQIISNIETDLVSLSQSPATS
SALVAFDEGWEALGPDAQAALQTAYITQNRHPSGAKHKLDRAEGEAAYHDAHETFHNGLRTLIEVKGYYDAFLINPEGDI
IYSVFKELDYATNLSDGKYAQSGLGAAYRAATKAAEREVVFADMDPYAPSAGAAAAFLATPVKGSDGSLIGVIAVQVPVD
MLGVITNNSDGLGKTAQVFLVGADFKARTKSRFDGGFGVLETLPEVDHIKEALRGETGFSVGTIGLDGHPVYAASRPLGL
ELANWALVVEQDVSDVMAPVRQKAWALVLIGLAVCTIMSLIGWRIATSITRPLHQIAVGMDRVASGDVATTVEEAQRSDE
IGDIGKSLLSLQEDLKVARDAEEQRIEQQREQEKVVENLSAGLLQLSQGDFSATIDTPFSGEHETLRADFNKTVTTLNET
LGHVVTAVSRIRNGAAEINQSSNDLSHRTESQAATLEETAAALEEMTASVKSAADSARSVETITGEAKQEAEASGKVVQN
AVTAMTEIEESSKQIAQIILVIDDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGESSK
QVESGVDLVGKAGEALNMIVERVNNIAQLVSGIAEGASEQSNGIEEINTGMVQLDQVTQQNAAMVEEASAACQMLDTDAS
ELGGVVAKFKLSGQTAQNTPTTSTAVSSAAASDSWDLDAETDETPMAPTAHGVPTSNGNAAYNFYEDF

Sequences:

>Translated_788_residues
MFRSKNMRISRKLPLLFAGFCAGTSFLLIAASLIAFNRFAERSVQDQMVSLLADRSYSVRQIISNIETDLVSLSQSPATS
SALVAFDEGWEALGPDAQAALQTAYITQNRHPSGAKHKLDRAEGEAAYHDAHETFHNGLRTLIEVKGYYDAFLINPEGDI
IYSVFKELDYATNLSDGKYAQSGLGAAYRAATKAAEREVVFADMDPYAPSAGAAAAFLATPVKGSDGSLIGVIAVQVPVD
MLGVITNNSDGLGKTAQVFLVGADFKARTKSRFDGGFGVLETLPEVDHIKEALRGETGFSVGTIGLDGHPVYAASRPLGL
ELANWALVVEQDVSDVMAPVRQKAWALVLIGLAVCTIMSLIGWRIATSITRPLHQIAVGMDRVASGDVATTVEEAQRSDE
IGDIGKSLLSLQEDLKVARDAEEQRIEQQREQEKVVENLSAGLLQLSQGDFSATIDTPFSGEHETLRADFNKTVTTLNET
LGHVVTAVSRIRNGAAEINQSSNDLSHRTESQAATLEETAAALEEMTASVKSAADSARSVETITGEAKQEAEASGKVVQN
AVTAMTEIEESSKQIAQIILVIDDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGESSK
QVESGVDLVGKAGEALNMIVERVNNIAQLVSGIAEGASEQSNGIEEINTGMVQLDQVTQQNAAMVEEASAACQMLDTDAS
ELGGVVAKFKLSGQTAQNTPTTSTAVSSAAASDSWDLDAETDETPMAPTAHGVPTSNGNAAYNFYEDF
>Mature_788_residues
MFRSKNMRISRKLPLLFAGFCAGTSFLLIAASLIAFNRFAERSVQDQMVSLLADRSYSVRQIISNIETDLVSLSQSPATS
SALVAFDEGWEALGPDAQAALQTAYITQNRHPSGAKHKLDRAEGEAAYHDAHETFHNGLRTLIEVKGYYDAFLINPEGDI
IYSVFKELDYATNLSDGKYAQSGLGAAYRAATKAAEREVVFADMDPYAPSAGAAAAFLATPVKGSDGSLIGVIAVQVPVD
MLGVITNNSDGLGKTAQVFLVGADFKARTKSRFDGGFGVLETLPEVDHIKEALRGETGFSVGTIGLDGHPVYAASRPLGL
ELANWALVVEQDVSDVMAPVRQKAWALVLIGLAVCTIMSLIGWRIATSITRPLHQIAVGMDRVASGDVATTVEEAQRSDE
IGDIGKSLLSLQEDLKVARDAEEQRIEQQREQEKVVENLSAGLLQLSQGDFSATIDTPFSGEHETLRADFNKTVTTLNET
LGHVVTAVSRIRNGAAEINQSSNDLSHRTESQAATLEETAAALEEMTASVKSAADSARSVETITGEAKQEAEASGKVVQN
AVTAMTEIEESSKQIAQIILVIDDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGESSK
QVESGVDLVGKAGEALNMIVERVNNIAQLVSGIAEGASEQSNGIEEINTGMVQLDQVTQQNAAMVEEASAACQMLDTDAS
ELGGVVAKFKLSGQTAQNTPTTSTAVSSAAASDSWDLDAETDETPMAPTAHGVPTSNGNAAYNFYEDF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=45.364238410596, Blast_Score=215, Evalue=9e-57,
Organism=Escherichia coli, GI2367378, Length=315, Percent_Identity=45.3968253968254, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1787690, Length=298, Percent_Identity=43.6241610738255, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1788194, Length=238, Percent_Identity=50.8403361344538, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=38.9121338912134, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 83580; Mature: 83580

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSKNMRISRKLPLLFAGFCAGTSFLLIAASLIAFNRFAERSVQDQMVSLLADRSYSVR
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QIISNIETDLVSLSQSPATSSALVAFDEGWEALGPDAQAALQTAYITQNRHPSGAKHKLD
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
RAEGEAAYHDAHETFHNGLRTLIEVKGYYDAFLINPEGDIIYSVFKELDYATNLSDGKYA
HHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHH
QSGLGAAYRAATKAAEREVVFADMDPYAPSAGAAAAFLATPVKGSDGSLIGVIAVQVPVD
HHCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEECCHH
MLGVITNNSDGLGKTAQVFLVGADFKARTKSRFDGGFGVLETLPEVDHIKEALRGETGFS
HHHEEECCCCCCCCEEEEEEEECCCHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCE
VGTIGLDGHPVYAASRPLGLELANWALVVEQDVSDVMAPVRQKAWALVLIGLAVCTIMSL
EEEECCCCCEEEECCCCCCCEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGWRIATSITRPLHQIAVGMDRVASGDVATTVEEAQRSDEIGDIGKSLLSLQEDLKVARD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
AEEQRIEQQREQEKVVENLSAGLLQLSQGDFSATIDTPFSGEHETLRADFNKTVTTLNET
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
LGHVVTAVSRIRNGAAEINQSSNDLSHRTESQAATLEETAAALEEMTASVKSAADSARSV
HHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETITGEAKQEAEASGKVVQNAVTAMTEIEESSKQIAQIILVIDDIAFQTNLLALNAGVEA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHH
ARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGESSKQVESGVDLVGKAGEALNMIV
HHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCHHHHHCCHHHHHHHH
ERVNNIAQLVSGIAEGASEQSNGIEEINTGMVQLDQVTQQNAAMVEEASAACQMLDTDAS
HHHHHHHHHHHHHHHCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ELGGVVAKFKLSGQTAQNTPTTSTAVSSAAASDSWDLDAETDETPMAPTAHGVPTSNGNA
HHCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
AYNFYEDF
EECCCCCC
>Mature Secondary Structure
MFRSKNMRISRKLPLLFAGFCAGTSFLLIAASLIAFNRFAERSVQDQMVSLLADRSYSVR
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QIISNIETDLVSLSQSPATSSALVAFDEGWEALGPDAQAALQTAYITQNRHPSGAKHKLD
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHH
RAEGEAAYHDAHETFHNGLRTLIEVKGYYDAFLINPEGDIIYSVFKELDYATNLSDGKYA
HHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHH
QSGLGAAYRAATKAAEREVVFADMDPYAPSAGAAAAFLATPVKGSDGSLIGVIAVQVPVD
HHCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEECCHH
MLGVITNNSDGLGKTAQVFLVGADFKARTKSRFDGGFGVLETLPEVDHIKEALRGETGFS
HHHEEECCCCCCCCEEEEEEEECCCHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCE
VGTIGLDGHPVYAASRPLGLELANWALVVEQDVSDVMAPVRQKAWALVLIGLAVCTIMSL
EEEECCCCCEEEECCCCCCCEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGWRIATSITRPLHQIAVGMDRVASGDVATTVEEAQRSDEIGDIGKSLLSLQEDLKVARD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
AEEQRIEQQREQEKVVENLSAGLLQLSQGDFSATIDTPFSGEHETLRADFNKTVTTLNET
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
LGHVVTAVSRIRNGAAEINQSSNDLSHRTESQAATLEETAAALEEMTASVKSAADSARSV
HHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETITGEAKQEAEASGKVVQNAVTAMTEIEESSKQIAQIILVIDDIAFQTNLLALNAGVEA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHH
ARAGEAGRGFAVVASEVRALAQRSSDAAMEIKTLIGESSKQVESGVDLVGKAGEALNMIV
HHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCHHHHHCCHHHHHHHH
ERVNNIAQLVSGIAEGASEQSNGIEEINTGMVQLDQVTQQNAAMVEEASAACQMLDTDAS
HHHHHHHHHHHHHHHCCCHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ELGGVVAKFKLSGQTAQNTPTTSTAVSSAAASDSWDLDAETDETPMAPTAHGVPTSNGNA
HHCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
AYNFYEDF
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]