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The map label for this gene is ybbO [H]

Identifier: 99082270

GI number: 99082270

Start: 2569211

End: 2570041

Strand: Reverse

Name: ybbO [H]

Synonym: TM1040_2430

Alternate gene names: 99082270

Gene position: 2570041-2569211 (Counterclockwise)

Preceding gene: 99082271

Following gene: 99082269

Centisome position: 80.29

GC content: 60.05

Gene sequence:

>831_bases
ATGACCAAGACTTTGCTGATTACCGGCTGCTCGTCGGGCATTGGCCATGCGGCAGCTCACGACATGCGCGCGCGCGGATG
GAGGGTTTTTGCCTCCTGCAGGCAGCAGCGTGATTGCGACCGGCTCCGAGCCGAAGGCTTTGAAAGTCCGCGGATTGATT
ACATCGATGCCCAAAGCATCCAGTCGGGGCTTGCTGAGGTACTGGCTGCCACCGGCGGTAGGCTAGATGCGCTGTTCAAC
AACGGTGCGCATGGCCTGCCGGGTGCGGTGGAGGATCTGCCGACCGAGGCGCTGCGCGAGATCTTCGAGACCAATGTCTT
TGGCTGGCATGAGCTTATCCGGCAGGTCATTCCTGTTATGCGCGCTCAGGGGCATGGGCGTATCGTGCAGAATTCCTCGG
TGCTGGGGCTGGTGACCTATCCTTGGCGCGGCGCCTATGCGGCGACGAAATTTGCTATCGAGGGGCTGAGTGACACGCTA
CGCCTTGAGCTTACGGGAAGCGGGATCGAGGTCATCCTGATCGAGCCGGGGCCGGTCACATCCAAGATCCGTGAAAACGC
GATTCCGCATTTTGAGAAGCATATCGACTGGAAAAACTCGCCAATCCGGGACCGCTACGAAGGGTCGTTGTTGAAACGGC
TCTATCACTCCAGCGGGCCAGATGCGTTTGAACTGCCTCCCTCCGCGGTATCCCGGAAACTTGCGCATGCTCTCGAGGCC
CGACGCCCGAAGCCGCGCTACTATGTCACCACCCCGACCTATATCGCCGGGACATTGCGCAGGATACTGTCGACGCGCGC
GATTGACCGCATCCTGTTGCGGTATAGATAG

Upstream 100 bases:

>100_bases
GCTGGAAAACCCGAAGACCGGCCAGGTGGGCTGGATTGCGGCTTCCCTGCTGAGCGCGAAACAGTCATAACTCGGCCCCG
GACAGATCCGGGGAACCACA

Downstream 100 bases:

>100_bases
ACGTTCCAATGCGCTGGCCGACGACCTAGCACGCTCCCGGCAGCAAACGACAACAAAGGATCACACCGATCATGGGCTCT
CCACTTTACATTCTGGGTAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTKTLLITGCSSGIGHAAAHDMRARGWRVFASCRQQRDCDRLRAEGFESPRIDYIDAQSIQSGLAEVLAATGGRLDALFN
NGAHGLPGAVEDLPTEALREIFETNVFGWHELIRQVIPVMRAQGHGRIVQNSSVLGLVTYPWRGAYAATKFAIEGLSDTL
RLELTGSGIEVILIEPGPVTSKIRENAIPHFEKHIDWKNSPIRDRYEGSLLKRLYHSSGPDAFELPPSAVSRKLAHALEA
RRPKPRYYVTTPTYIAGTLRRILSTRAIDRILLRYR

Sequences:

>Translated_276_residues
MTKTLLITGCSSGIGHAAAHDMRARGWRVFASCRQQRDCDRLRAEGFESPRIDYIDAQSIQSGLAEVLAATGGRLDALFN
NGAHGLPGAVEDLPTEALREIFETNVFGWHELIRQVIPVMRAQGHGRIVQNSSVLGLVTYPWRGAYAATKFAIEGLSDTL
RLELTGSGIEVILIEPGPVTSKIRENAIPHFEKHIDWKNSPIRDRYEGSLLKRLYHSSGPDAFELPPSAVSRKLAHALEA
RRPKPRYYVTTPTYIAGTLRRILSTRAIDRILLRYR
>Mature_275_residues
TKTLLITGCSSGIGHAAAHDMRARGWRVFASCRQQRDCDRLRAEGFESPRIDYIDAQSIQSGLAEVLAATGGRLDALFNN
GAHGLPGAVEDLPTEALREIFETNVFGWHELIRQVIPVMRAQGHGRIVQNSSVLGLVTYPWRGAYAATKFAIEGLSDTLR
LELTGSGIEVILIEPGPVTSKIRENAIPHFEKHIDWKNSPIRDRYEGSLLKRLYHSSGPDAFELPPSAVSRKLAHALEAR
RPKPRYYVTTPTYIAGTLRRILSTRAIDRILLRYR

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=290, Percent_Identity=30.6896551724138, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI223718074, Length=266, Percent_Identity=31.9548872180451, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI19743808, Length=255, Percent_Identity=30.1960784313725, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI150247226, Length=255, Percent_Identity=29.8039215686275, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI40548397, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI214010158, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI214010156, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI22758144, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI44680136, Length=272, Percent_Identity=28.3088235294118, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI44680133, Length=272, Percent_Identity=28.3088235294118, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI17738292, Length=272, Percent_Identity=28.3088235294118, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI22507405, Length=285, Percent_Identity=29.4736842105263, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI119392083, Length=261, Percent_Identity=30.6513409961686, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=32.6424870466321, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=31.1224489795918, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI50726952, Length=264, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4504503, Length=261, Percent_Identity=27.9693486590038, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=26.8817204301075, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786701, Length=272, Percent_Identity=38.6029411764706, Blast_Score=190, Evalue=9e-50,
Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=31.3513513513514, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=32.6315789473684, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786812, Length=184, Percent_Identity=29.8913043478261, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71997402, Length=189, Percent_Identity=31.7460317460317, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193210355, Length=263, Percent_Identity=27.3764258555133, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115534660, Length=260, Percent_Identity=26.1538461538462, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=266, Percent_Identity=23.6842105263158, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17570069, Length=188, Percent_Identity=26.5957446808511, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=270, Percent_Identity=24.4444444444444, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=270, Percent_Identity=24.4444444444444, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=29.5546558704453, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322067, Length=243, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=30.1020408163265, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24651139, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=29.4736842105263, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580925, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=193, Percent_Identity=26.9430051813472, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=184, Percent_Identity=27.7173913043478, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30766; Mature: 30634

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTLLITGCSSGIGHAAAHDMRARGWRVFASCRQQRDCDRLRAEGFESPRIDYIDAQSI
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHHH
QSGLAEVLAATGGRLDALFNNGAHGLPGAVEDLPTEALREIFETNVFGWHELIRQVIPVM
HHHHHHHHHHCCCCEEHHHCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RAQGHGRIVQNSSVLGLVTYPWRGAYAATKFAIEGLSDTLRLELTGSGIEVILIEPGPVT
HCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCH
SKIRENAIPHFEKHIDWKNSPIRDRYEGSLLKRLYHSSGPDAFELPPSAVSRKLAHALEA
HHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
RRPKPRYYVTTPTYIAGTLRRILSTRAIDRILLRYR
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKTLLITGCSSGIGHAAAHDMRARGWRVFASCRQQRDCDRLRAEGFESPRIDYIDAQSI
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHHH
QSGLAEVLAATGGRLDALFNNGAHGLPGAVEDLPTEALREIFETNVFGWHELIRQVIPVM
HHHHHHHHHHCCCCEEHHHCCCCCCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RAQGHGRIVQNSSVLGLVTYPWRGAYAATKFAIEGLSDTLRLELTGSGIEVILIEPGPVT
HCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCH
SKIRENAIPHFEKHIDWKNSPIRDRYEGSLLKRLYHSSGPDAFELPPSAVSRKLAHALEA
HHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
RRPKPRYYVTTPTYIAGTLRRILSTRAIDRILLRYR
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]