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The map label for this gene is etfA [H]

Identifier: 99082266

GI number: 99082266

Start: 2566366

End: 2567295

Strand: Reverse

Name: etfA [H]

Synonym: TM1040_2426

Alternate gene names: 99082266

Gene position: 2567295-2566366 (Counterclockwise)

Preceding gene: 99082267

Following gene: 99082264

Centisome position: 80.2

GC content: 61.29

Gene sequence:

>930_bases
ATGGCTGTTCTTCTCCTTGCCGAAGTCAACGCGGGTGAACTGGCGCTTGATGCGACCGCAAAGGCTGTTTCTGCTGCAAA
GTCGCTGGGCGATGTTACTGTTCTGGCTGCTGGGGCGTCCGCCGCTGCAGCGGGCGAAGCTGCCGCCAAAATCGATGGCG
TAGCCAAGGTGCTGGTAGCCGAAGACGAAAGCCTCGGCCACCGTCTTGCAGAACCCACAGCGGCTCTGGTTGCTGCGCTG
GCCAGCGACTACAGCCACATTGTCGCGCCTGCTACCACCGACGCCAAAAACATCCTGCCCCGCGTGGCGGCACTTCTGGA
TGTGATGGTGATCTCCGACGTGACGGCCGTTGTCGACGCTGACACCTTCGAGCGCCCGATCTACGCAGGCAACGCCATTC
AGGTGGTGAAATCTGCGGATGCAAAAAAGGTGATCTCCTTCCGGACTTCCACCTTTGATGCAGCCGGAGAAGGCGGTGCG
GCGTCTGTGGAGACCATCTCCGCGACCGAGAACCCCGGCCTCAGCTCTTGGGTCGAAGACAAGCTCGCCGAAAGCGATCG
TCCAGAGCTCACATCTGCGGGTGTGGTTGTCTCCGGCGGCCGTGGGGTTGGCTCCGAAGAAGACTTCAAGATCATCGAAG
CCCTGGCCGACAAGCTGGGTGCGGCTGTTGGTGCGTCCCGCGCAGCCGTCGACTCCGGCTTTGCGCCGAACGACTGGCAG
GTGGGTCAGACCGGTAAAGTCGTAGCGCCCGAGCTCTACATCGCAGTTGGCATCTCCGGTGCGATCCAGCACCTTGCCGG
GATGAAGGACTCCAAGATCATCGTCGCGATCAACAAAGACGAAGAAGCGCCGATCTTCCAGGTGGCGGACTACGGTCTGG
TCGCAGACCTGTTCCAGGCCGTGCCTGAGCTGACGGAAAAGCTGGGTTAA

Upstream 100 bases:

>100_bases
CCGTGGTGGAGACCAAGGAACCCGAAGCCCGCTCCGCAGGTGTCATCGTGGGATCCGTGGACGAGCTGGTTGCGAAACTC
AAAGAAGCGGGAGCTGTGTA

Downstream 100 bases:

>100_bases
ACCCCACCGCTTTGGATTTGAAAAGGCCCATGCAGCGCATGGGCCTTTTTTCTTGAGCGAAGGGCTCGAGTTACGCTGTC
GAGAGCATCTTTAGCAGCCG

Product: electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAVLLLAEVNAGELALDATAKAVSAAKSLGDVTVLAAGASAAAAGEAAAKIDGVAKVLVAEDESLGHRLAEPTAALVAAL
ASDYSHIVAPATTDAKNILPRVAALLDVMVISDVTAVVDADTFERPIYAGNAIQVVKSADAKKVISFRTSTFDAAGEGGA
ASVETISATENPGLSSWVEDKLAESDRPELTSAGVVVSGGRGVGSEEDFKIIEALADKLGAAVGASRAAVDSGFAPNDWQ
VGQTGKVVAPELYIAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFQAVPELTEKLG

Sequences:

>Translated_309_residues
MAVLLLAEVNAGELALDATAKAVSAAKSLGDVTVLAAGASAAAAGEAAAKIDGVAKVLVAEDESLGHRLAEPTAALVAAL
ASDYSHIVAPATTDAKNILPRVAALLDVMVISDVTAVVDADTFERPIYAGNAIQVVKSADAKKVISFRTSTFDAAGEGGA
ASVETISATENPGLSSWVEDKLAESDRPELTSAGVVVSGGRGVGSEEDFKIIEALADKLGAAVGASRAAVDSGFAPNDWQ
VGQTGKVVAPELYIAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFQAVPELTEKLG
>Mature_308_residues
AVLLLAEVNAGELALDATAKAVSAAKSLGDVTVLAAGASAAAAGEAAAKIDGVAKVLVAEDESLGHRLAEPTAALVAALA
SDYSHIVAPATTDAKNILPRVAALLDVMVISDVTAVVDADTFERPIYAGNAIQVVKSADAKKVISFRTSTFDAAGEGGAA
SVETISATENPGLSSWVEDKLAESDRPELTSAGVVVSGGRGVGSEEDFKIIEALADKLGAAVGASRAAVDSGFAPNDWQV
GQTGKVVAPELYIAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFQAVPELTEKLG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=294, Percent_Identity=58.5034013605442, Blast_Score=317, Evalue=8e-87,
Organism=Homo sapiens, GI189181759, Length=276, Percent_Identity=60.1449275362319, Blast_Score=307, Evalue=6e-84,
Organism=Escherichia coli, GI1786226, Length=228, Percent_Identity=35.0877192982456, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787990, Length=263, Percent_Identity=32.6996197718631, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082157, Length=263, Percent_Identity=31.1787072243346, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=55.3054662379421, Blast_Score=310, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6325261, Length=287, Percent_Identity=48.780487804878, Blast_Score=261, Evalue=7e-71,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=59.2948717948718, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=59.2948717948718, Blast_Score=322, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31247; Mature: 31116

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLLLAEVNAGELALDATAKAVSAAKSLGDVTVLAAGASAAAAGEAAAKIDGVAKVLVA
CEEEEEEECCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCHHHCCHHHHHHHHHEEEEEE
EDESLGHRLAEPTAALVAALASDYSHIVAPATTDAKNILPRVAALLDVMVISDVTAVVDA
CCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DTFERPIYAGNAIQVVKSADAKKVISFRTSTFDAAGEGGAASVETISATENPGLSSWVED
CHHCCCCCCCCHHEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
KLAESDRPELTSAGVVVSGGRGVGSEEDFKIIEALADKLGAAVGASRAAVDSGFAPNDWQ
HHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPELYIAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFQA
CCCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH
VPELTEKLG
HHHHHHHCC
>Mature Secondary Structure 
AVLLLAEVNAGELALDATAKAVSAAKSLGDVTVLAAGASAAAAGEAAAKIDGVAKVLVA
EEEEEEECCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCHHHCCHHHHHHHHHEEEEEE
EDESLGHRLAEPTAALVAALASDYSHIVAPATTDAKNILPRVAALLDVMVISDVTAVVDA
CCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DTFERPIYAGNAIQVVKSADAKKVISFRTSTFDAAGEGGAASVETISATENPGLSSWVED
CHHCCCCCCCCHHEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
KLAESDRPELTSAGVVVSGGRGVGSEEDFKIIEALADKLGAAVGASRAAVDSGFAPNDWQ
HHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPELYIAVGISGAIQHLAGMKDSKIIVAINKDEEAPIFQVADYGLVADLFQA
CCCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH
VPELTEKLG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8376381; 1576992; 10026281 [H]