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The map label for this gene is dhbF [H]

Identifier: 99082242

GI number: 99082242

Start: 2535708

End: 2540267

Strand: Direct

Name: dhbF [H]

Synonym: TM1040_2402

Alternate gene names: 99082242

Gene position: 2535708-2540267 (Clockwise)

Preceding gene: 99082241

Following gene: 99082243

Centisome position: 79.22

GC content: 61.34

Gene sequence:

>4560_bases
ATGACTATTTCAACCGTCGTCATTGGCAATGAATCCCTGCTGATCGGTTGTTGCGAGGCCTTGCTGGCACGCGGTCATGA
TATTCGCGCCGTCGTCAGCACAGATGCTGAGATCACCTCTTGGGCAGCCTCCAAGGGTTTGAACACACATTCTAAGCCGC
TAGAGATTGACATTGAATTCGACTGGCTTTTGTCGATTGCAAACCTGCAGGTCCTGCCAGAGGCGGTGATCTCCAAAGCG
CGACTGGGGGCGGTCAACTTTCACGATGGCCCGCTGCCAGACCGGGCGGGTCTCAATACGCCAAATTGGGCCATTCTCGA
AGGCGCTGAAGAGCATGGCATCACGTGGCACCTGATCGAAGGCGGCGTCGACGAGGGCGATATTCTGGCCCAGCGCCGGT
TTGCGATTGCACCAGATGAGACGGCCTTTAGCCTCAACTCCAAATGCTACGGTGCTGCACTCGACAGCTTTGGCGAAGTG
CTCGAGCAACTCGAGAGCGGCGCACTAGAGCGCACGCCGCAAGACCTCAGCCATCGCCGCTATCATGCACGCAAGGATCG
CCCCGATGCGGCTGGCTTCTTGCGGTTTGACCGCAACCGCGACACGCTTTTGTGTCTGGTGCGGGGCCTTGATATGGGCG
GCTATTGGAACCCGTTGACCACGGCCAAAATCCGCTTGCCGGGACAGGTCGCTGCGGTCGGTGCAGCGCAAGCCACCGAA
GGCGAGGGTATTCCGGGGGAAGTTCTCGCGGTGAGCGCAAATGCTCTGACCGTCGCCTGCGCCGATGGTGCAATAGAACT
GCGCGACCTGAAGACCCTCTCGGGAGGGGCGTTGCAGCCCTCTGCCCTCCTCGAAGTGGGTGATGTGCTGCCCACCCTCT
CCGATCAAGAGGTGGAGGCCCTCAATGCGGCGGCGCAGACCTGCCAAAAGGCGGAACCTTATTGGCGCCGCTCTTTGGCT
GAGATGCTACCCTTGCCCGTGCCACTGCAGGGCGCGGAACTCGACGTCGAGGCCACTGCCGACATCCAGTTGCCGACGGA
TTGTGCGCCCCAGACCCTGATGGCCGCAATGCTGGCGTGGCTGTTGCAGAGCCTCGGTGAGACCGCAGGCTCAATCGCGC
TCTCGCTACCGGATCTACAAACGTCAGACGACTTGGGAGTGCTTTCAAACTGGGTGCCGCTGAGCGCGGAGATCGACGAA
AAGATCAAAACTGTAGAGGCCCGCGCGGCCGAGGTTCTGGACCGCTTGGACAACATGGGGGGCTTTGCAACCGACCTCAT
CCTGCGCGCGCCGGAAGTCACGATTGAAACACCTCCAGAGGTTGCGCTGTGCCTTGGGACGAACCTCGCCCCCGCACAGG
CCAAACTGGCCCTGATCCAGTCGGATAGCCGATTGCAGCTGCGCTCTTGCCAGCTATCACCCGAGGCGCTGTCGATGCTG
GCTGCGCGGCTTCAGTGCCTCTTGAACACGCTGCCCGAAGACGGTGCAGCGACGCTCTCCACGCTGCCAATGCTGCCAGA
TTCAGAGCGGACGCGCCTGATTGAGACATGGAACGATACCGGTTGTGACTACCCCACAGATCAAACCATTCACGCCGCTT
TTGAGGCGCAGGTGGCAAGAACCCCAGATGCGATAGCGGTCGTTTTTGAAGATCAACAGCTGACCTATCGCGCGTTGAAC
CAACGCGCTGACGCGCTGGCCCGACATCTGCATGACCTCGGTGCAAAACCGGGCAGCCATGTGGGCGTGTATCTGCGTCG
CTCCATGGATCTGGTGATTGCAACGCTTGGTATTTTGAAGGCCGGCGCGGCCTATGTACCGCTTGATCCTACCTACCCTG
CCGACCGTATCGCGCATTACATCACCGACAGTCAGGCCGCGGTCATTGTCACCCATGAAAGCCTCGCTGCGGAACTCCCC
GAAAGCGATGCCAGGCAGCTGCATCTCGACGCGCTCGACCTCACAACCGAGGCGGACCCGATCCGGGCAGGTGCTGCCGA
AGATCTCGCGTATCTGATCTATACCTCAGGCTCCACGGGCTTGCCAAAAGGCGTGATGGTGCGTCATCGCAATGTGGCGA
ACTTCTTTACCGCGATGGATGCGCGCATCCCCCATCAGCCGGGAGACGCCTGGCTCGCGGTGACAAGCCTCTCGTTTGAT
ATTTCGGTGCTGGAGCTTTTCTGGACGCTTGCGCGCGGCTTCAAACTGGTGCTCTCCAGCGACGAAAGCCGCCTACAGCT
GGCCAACGGTCCCATCGGGCTCAGCGATCGCAAGATGGATTTCAATCTCTATTACTGGGGCAATGACGACGGCGCGGGCG
AAAAGAAATACGAATTGCTTCTAGAGGGCGCCAAGTTTGCGGATGCCCATGGGTTCAATGCGGTCTGGACGCCAGAGCGG
CACTTCCACGCCTTTGGTGGCCCCTACCCGAACCCCTCCGTGACCGGTGCCGCCGTGGCAGCGGTGACCCGCAATATCGG
TGTGCGGGCCGGCTCCTGTGTGGCGCCGCTTCATCACCCCGCGCGCATCGCCGAAGAATGGGCGGTCATCGACAATCTGA
CGGGCGGGCGCGCGGGTATTGGCTTTGCCTCGGGCTGGCAGCCGGATGACTTCATCTTGCGCCCCGAGAACACGCCGCCT
GCCAACAAACCAGCGCTGTTTGAAGCCCTTCAGACAGTGCGAAAGCTCTGGCGAGGCGAAGAAGTCGCTTTCCCGCGCGC
GGATGGTGGCCAGCATTCGGTGGTCACGCAACCACGCCCGGTTTCAGAGGAACTTGCCGTCTGGGTCACCACGGCAGGCA
ACCCGGAGACATGGCGCGAGGCTGGGCGCGTGGGGGCCAATGTGCTTACGCATCTTCTAGGCCAGAGTATCGACGAGGTC
GGCGACAAGATCGCGCTATACCATGCCGCGCTGCGCGAGGCGGGGTATGACCCGGCGGATTTCACCGTGACACTCATGTT
GCACACCTATCTCGCCGAGACCCGCGAGGCCGCCCGCGAGGTGGCGCGCGAGCCGATGAAGGACTACCTGCGCTCTGCGG
CTGGGCTCATTAAACAGTATGCCTGGGCTTTTCCAGCGTTCAAACGCCCAAAGGGCGTCGACAATCCCTTTGAAATGGAT
CTTGGCAGTCTCAGCAGCGAGGAGCTGGAAGCCATCCTCGATTTCGCATTTGAGCGATACTTCGAAGAGTCAGGTCTCTT
TGGCACGGTCGACGACGCAGTCGCGCGCGTCGAGGATCTCAAGCGCATCGGCGTCGATGAGGTCGCCTGCCTGATTGATT
ATGGGATTGCACCGCATGTGGTGCTTGAAGGGCTCAAACCCCTTGCAGAAGTCCTGCGCCGCTCCAATCGCGTGCAAGAG
TTGGCAAATGATGACTTCTCGCTCGCCGCGCAGATCGTGCGTCACGGGGTGACGCATATGCAATGCACCCCCTCGATGGC
GCGCATGATTGCCTCTGATGCAGATGCAAGCCCCGCGCTCGGGCGCTTGCGACACCTTCTCGTTGGCGGCGAGGCCTTGC
CCGGCGATCTTGTTGCCGCCCTGCGCGAGCAGACCAGGGCCACGCTTCACAATATGTATGGCCCCACTGAGACTACGATC
TGGTCCACGGTTGAAACGCTGGAACGCGCCCCAACGGGTATTGCCCCGATCGGAACGCCTGTGGCCAATAACTCTGTCTA
CGTTCTCGACGCCAAGGGGCAACTCGCCCCCGTCGGGGCGGCAGGTGAACTCTACATCGGCGGCGCAGGCGTGACGGCCG
GGTATTGGCGGCGCGACGCGCTCACGGCCGAACGGTTCCCCGATGATCCCTTCCTGTCAGGGCAAAAGATGTATCGTACC
GGGGATTTGGTGCGGTGGCGCGAGGACGGCAAGCTCGATTTTCTCGGGCGCACGGATCATCAGGTCAAGATCCGCGGCCA
GCGGATCGAACTGGGCGAAATCGAAACCGCGCTGACCGCAGTCGAGGGCGTGACCGCTGCCGTTGTGATCCCACGCAAGG
TCGGCTCAGACGAGCGGCTGGTTGGCTATGTCACCGCATCCGGCGTTTTCTCAGAGACCGAGGCCAAGGCACAACTGTCG
CGGCAACTCGCCGGGGCAATGGTGCCGTCACACATAGTGGTGCTTGAGGCTTTCCCTCTGACGCCCAACAAGAAAATCGA
CCGCAAGGCGCTGCCCGACCCAACCCCCAGCCGACAAGAAGCACATGTAATCTCTGCCGAACCTCAGTCGCCCGTACAGC
AGAAGATCTCGGAGATCTGGAAGGCGCTCCTTGGCGTGCCGGCTGTTGGCAAAAGCGATAATTTCTTTGCGCTCGGTGGG
CATTCCCTATTGGCGGTTCAGGCTCATCGCGACATTCGCAGCGCGCTTGAGGTCGAGCGGTTGTCGATCACGGATATCTT
CCGCTTTCCGACCCTTGACGGGTTGGCCTCACACCTGGAACACCTGCAGACCGGCGACACCACGGTTGCGGAGACGTCCC
CTGCCGCCCCGGCAGGGCGTGCAGACACCATGTCCAAACGCCGCGCAATGCGCGCCAATCGCAAAGCCCGCTCTGGATGA

Upstream 100 bases:

>100_bases
ACTTGACGCGCCATCATGTCAAACGCGCGCTTCGGCCACGTCCCGCACCGCGCCCCGCACGGCCCTTTGCACCTGACCCC
GTCTTGGAGGACAACAAGTC

Downstream 100 bases:

>100_bases
TTGCACCCCGACCCGCGCCACAGGATATCTCGCAGCAGCGCCAGCACGCGCTGCGCCAACTCTTGTCAGATCCGATCGCA
ATCGCCACCTGCGACCCACA

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1519; Mature: 1518

Protein sequence:

>1519_residues
MTISTVVIGNESLLIGCCEALLARGHDIRAVVSTDAEITSWAASKGLNTHSKPLEIDIEFDWLLSIANLQVLPEAVISKA
RLGAVNFHDGPLPDRAGLNTPNWAILEGAEEHGITWHLIEGGVDEGDILAQRRFAIAPDETAFSLNSKCYGAALDSFGEV
LEQLESGALERTPQDLSHRRYHARKDRPDAAGFLRFDRNRDTLLCLVRGLDMGGYWNPLTTAKIRLPGQVAAVGAAQATE
GEGIPGEVLAVSANALTVACADGAIELRDLKTLSGGALQPSALLEVGDVLPTLSDQEVEALNAAAQTCQKAEPYWRRSLA
EMLPLPVPLQGAELDVEATADIQLPTDCAPQTLMAAMLAWLLQSLGETAGSIALSLPDLQTSDDLGVLSNWVPLSAEIDE
KIKTVEARAAEVLDRLDNMGGFATDLILRAPEVTIETPPEVALCLGTNLAPAQAKLALIQSDSRLQLRSCQLSPEALSML
AARLQCLLNTLPEDGAATLSTLPMLPDSERTRLIETWNDTGCDYPTDQTIHAAFEAQVARTPDAIAVVFEDQQLTYRALN
QRADALARHLHDLGAKPGSHVGVYLRRSMDLVIATLGILKAGAAYVPLDPTYPADRIAHYITDSQAAVIVTHESLAAELP
ESDARQLHLDALDLTTEADPIRAGAAEDLAYLIYTSGSTGLPKGVMVRHRNVANFFTAMDARIPHQPGDAWLAVTSLSFD
ISVLELFWTLARGFKLVLSSDESRLQLANGPIGLSDRKMDFNLYYWGNDDGAGEKKYELLLEGAKFADAHGFNAVWTPER
HFHAFGGPYPNPSVTGAAVAAVTRNIGVRAGSCVAPLHHPARIAEEWAVIDNLTGGRAGIGFASGWQPDDFILRPENTPP
ANKPALFEALQTVRKLWRGEEVAFPRADGGQHSVVTQPRPVSEELAVWVTTAGNPETWREAGRVGANVLTHLLGQSIDEV
GDKIALYHAALREAGYDPADFTVTLMLHTYLAETREAAREVAREPMKDYLRSAAGLIKQYAWAFPAFKRPKGVDNPFEMD
LGSLSSEELEAILDFAFERYFEESGLFGTVDDAVARVEDLKRIGVDEVACLIDYGIAPHVVLEGLKPLAEVLRRSNRVQE
LANDDFSLAAQIVRHGVTHMQCTPSMARMIASDADASPALGRLRHLLVGGEALPGDLVAALREQTRATLHNMYGPTETTI
WSTVETLERAPTGIAPIGTPVANNSVYVLDAKGQLAPVGAAGELYIGGAGVTAGYWRRDALTAERFPDDPFLSGQKMYRT
GDLVRWREDGKLDFLGRTDHQVKIRGQRIELGEIETALTAVEGVTAAVVIPRKVGSDERLVGYVTASGVFSETEAKAQLS
RQLAGAMVPSHIVVLEAFPLTPNKKIDRKALPDPTPSRQEAHVISAEPQSPVQQKISEIWKALLGVPAVGKSDNFFALGG
HSLLAVQAHRDIRSALEVERLSITDIFRFPTLDGLASHLEHLQTGDTTVAETSPAAPAGRADTMSKRRAMRANRKARSG

Sequences:

>Translated_1519_residues
MTISTVVIGNESLLIGCCEALLARGHDIRAVVSTDAEITSWAASKGLNTHSKPLEIDIEFDWLLSIANLQVLPEAVISKA
RLGAVNFHDGPLPDRAGLNTPNWAILEGAEEHGITWHLIEGGVDEGDILAQRRFAIAPDETAFSLNSKCYGAALDSFGEV
LEQLESGALERTPQDLSHRRYHARKDRPDAAGFLRFDRNRDTLLCLVRGLDMGGYWNPLTTAKIRLPGQVAAVGAAQATE
GEGIPGEVLAVSANALTVACADGAIELRDLKTLSGGALQPSALLEVGDVLPTLSDQEVEALNAAAQTCQKAEPYWRRSLA
EMLPLPVPLQGAELDVEATADIQLPTDCAPQTLMAAMLAWLLQSLGETAGSIALSLPDLQTSDDLGVLSNWVPLSAEIDE
KIKTVEARAAEVLDRLDNMGGFATDLILRAPEVTIETPPEVALCLGTNLAPAQAKLALIQSDSRLQLRSCQLSPEALSML
AARLQCLLNTLPEDGAATLSTLPMLPDSERTRLIETWNDTGCDYPTDQTIHAAFEAQVARTPDAIAVVFEDQQLTYRALN
QRADALARHLHDLGAKPGSHVGVYLRRSMDLVIATLGILKAGAAYVPLDPTYPADRIAHYITDSQAAVIVTHESLAAELP
ESDARQLHLDALDLTTEADPIRAGAAEDLAYLIYTSGSTGLPKGVMVRHRNVANFFTAMDARIPHQPGDAWLAVTSLSFD
ISVLELFWTLARGFKLVLSSDESRLQLANGPIGLSDRKMDFNLYYWGNDDGAGEKKYELLLEGAKFADAHGFNAVWTPER
HFHAFGGPYPNPSVTGAAVAAVTRNIGVRAGSCVAPLHHPARIAEEWAVIDNLTGGRAGIGFASGWQPDDFILRPENTPP
ANKPALFEALQTVRKLWRGEEVAFPRADGGQHSVVTQPRPVSEELAVWVTTAGNPETWREAGRVGANVLTHLLGQSIDEV
GDKIALYHAALREAGYDPADFTVTLMLHTYLAETREAAREVAREPMKDYLRSAAGLIKQYAWAFPAFKRPKGVDNPFEMD
LGSLSSEELEAILDFAFERYFEESGLFGTVDDAVARVEDLKRIGVDEVACLIDYGIAPHVVLEGLKPLAEVLRRSNRVQE
LANDDFSLAAQIVRHGVTHMQCTPSMARMIASDADASPALGRLRHLLVGGEALPGDLVAALREQTRATLHNMYGPTETTI
WSTVETLERAPTGIAPIGTPVANNSVYVLDAKGQLAPVGAAGELYIGGAGVTAGYWRRDALTAERFPDDPFLSGQKMYRT
GDLVRWREDGKLDFLGRTDHQVKIRGQRIELGEIETALTAVEGVTAAVVIPRKVGSDERLVGYVTASGVFSETEAKAQLS
RQLAGAMVPSHIVVLEAFPLTPNKKIDRKALPDPTPSRQEAHVISAEPQSPVQQKISEIWKALLGVPAVGKSDNFFALGG
HSLLAVQAHRDIRSALEVERLSITDIFRFPTLDGLASHLEHLQTGDTTVAETSPAAPAGRADTMSKRRAMRANRKARSG
>Mature_1518_residues
TISTVVIGNESLLIGCCEALLARGHDIRAVVSTDAEITSWAASKGLNTHSKPLEIDIEFDWLLSIANLQVLPEAVISKAR
LGAVNFHDGPLPDRAGLNTPNWAILEGAEEHGITWHLIEGGVDEGDILAQRRFAIAPDETAFSLNSKCYGAALDSFGEVL
EQLESGALERTPQDLSHRRYHARKDRPDAAGFLRFDRNRDTLLCLVRGLDMGGYWNPLTTAKIRLPGQVAAVGAAQATEG
EGIPGEVLAVSANALTVACADGAIELRDLKTLSGGALQPSALLEVGDVLPTLSDQEVEALNAAAQTCQKAEPYWRRSLAE
MLPLPVPLQGAELDVEATADIQLPTDCAPQTLMAAMLAWLLQSLGETAGSIALSLPDLQTSDDLGVLSNWVPLSAEIDEK
IKTVEARAAEVLDRLDNMGGFATDLILRAPEVTIETPPEVALCLGTNLAPAQAKLALIQSDSRLQLRSCQLSPEALSMLA
ARLQCLLNTLPEDGAATLSTLPMLPDSERTRLIETWNDTGCDYPTDQTIHAAFEAQVARTPDAIAVVFEDQQLTYRALNQ
RADALARHLHDLGAKPGSHVGVYLRRSMDLVIATLGILKAGAAYVPLDPTYPADRIAHYITDSQAAVIVTHESLAAELPE
SDARQLHLDALDLTTEADPIRAGAAEDLAYLIYTSGSTGLPKGVMVRHRNVANFFTAMDARIPHQPGDAWLAVTSLSFDI
SVLELFWTLARGFKLVLSSDESRLQLANGPIGLSDRKMDFNLYYWGNDDGAGEKKYELLLEGAKFADAHGFNAVWTPERH
FHAFGGPYPNPSVTGAAVAAVTRNIGVRAGSCVAPLHHPARIAEEWAVIDNLTGGRAGIGFASGWQPDDFILRPENTPPA
NKPALFEALQTVRKLWRGEEVAFPRADGGQHSVVTQPRPVSEELAVWVTTAGNPETWREAGRVGANVLTHLLGQSIDEVG
DKIALYHAALREAGYDPADFTVTLMLHTYLAETREAAREVAREPMKDYLRSAAGLIKQYAWAFPAFKRPKGVDNPFEMDL
GSLSSEELEAILDFAFERYFEESGLFGTVDDAVARVEDLKRIGVDEVACLIDYGIAPHVVLEGLKPLAEVLRRSNRVQEL
ANDDFSLAAQIVRHGVTHMQCTPSMARMIASDADASPALGRLRHLLVGGEALPGDLVAALREQTRATLHNMYGPTETTIW
STVETLERAPTGIAPIGTPVANNSVYVLDAKGQLAPVGAAGELYIGGAGVTAGYWRRDALTAERFPDDPFLSGQKMYRTG
DLVRWREDGKLDFLGRTDHQVKIRGQRIELGEIETALTAVEGVTAAVVIPRKVGSDERLVGYVTASGVFSETEAKAQLSR
QLAGAMVPSHIVVLEAFPLTPNKKIDRKALPDPTPSRQEAHVISAEPQSPVQQKISEIWKALLGVPAVGKSDNFFALGGH
SLLAVQAHRDIRSALEVERLSITDIFRFPTLDGLASHLEHLQTGDTTVAETSPAAPAGRADTMSKRRAMRANRKARSG

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=358, Percent_Identity=25.9776536312849, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI157311624, Length=283, Percent_Identity=26.1484098939929, Blast_Score=72, Evalue=4e-12,
Organism=Homo sapiens, GI157311622, Length=283, Percent_Identity=26.1484098939929, Blast_Score=72, Evalue=4e-12,
Organism=Escherichia coli, GI1786801, Length=345, Percent_Identity=40.8695652173913, Blast_Score=200, Evalue=6e-52,
Organism=Escherichia coli, GI1788589, Length=310, Percent_Identity=27.0967741935484, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI145693145, Length=237, Percent_Identity=29.535864978903, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786810, Length=252, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI221142682, Length=187, Percent_Identity=25.1336898395722, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17556356, Length=343, Percent_Identity=30.9037900874636, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17550940, Length=309, Percent_Identity=25.2427184466019, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=264, Percent_Identity=26.1363636363636, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32563687, Length=167, Percent_Identity=27.5449101796407, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=454, Percent_Identity=27.3127753303965, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24648676, Length=356, Percent_Identity=28.6516853932584, Blast_Score=116, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24582852, Length=275, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552801, Length=197, Percent_Identity=30.4568527918782, Blast_Score=77, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45550496, Length=197, Percent_Identity=30.4568527918782, Blast_Score=77, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24581924, Length=281, Percent_Identity=27.4021352313167, Blast_Score=74, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 164083; Mature: 163951

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISTVVIGNESLLIGCCEALLARGHDIRAVVSTDAEITSWAASKGLNTHSKPLEIDIEF
CEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEEEEH
DWLLSIANLQVLPEAVISKARLGAVNFHDGPLPDRAGLNTPNWAILEGAEEHGITWHLIE
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEEECCHHCCCEEEEEE
GGVDEGDILAQRRFAIAPDETAFSLNSKCYGAALDSFGEVLEQLESGALERTPQDLSHRR
CCCCCCHHHHHCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
YHARKDRPDAAGFLRFDRNRDTLLCLVRGLDMGGYWNPLTTAKIRLPGQVAAVGAAQATE
HHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCEEECCCCCCCC
GEGIPGEVLAVSANALTVACADGAIELRDLKTLSGGALQPSALLEVGDVLPTLSDQEVEA
CCCCCCCEEEEECCEEEEEECCCCEEEEHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
LNAAAQTCQKAEPYWRRSLAEMLPLPVPLQGAELDVEATADIQLPTDCAPQTLMAAMLAW
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEECEEEEECEECCCCCCHHHHHHHHHHH
LLQSLGETAGSIALSLPDLQTSDDLGVLSNWVPLSAEIDEKIKTVEARAAEVLDRLDNMG
HHHHHHHCCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GFATDLILRAPEVTIETPPEVALCLGTNLAPAQAKLALIQSDSRLQLRSCQLSPEALSML
CHHHHHHEECCCCEECCCCCEEEEECCCCCCCHHEEEEEECCCCEEEHHCCCCHHHHHHH
AARLQCLLNTLPEDGAATLSTLPMLPDSERTRLIETWNDTGCDYPTDQTIHAAFEAQVAR
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHEEECCCCCCCCCCCCCHHHHHHHHHHHC
TPDAIAVVFEDQQLTYRALNQRADALARHLHDLGAKPGSHVGVYLRRSMDLVIATLGILK
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHH
AGAAYVPLDPTYPADRIAHYITDSQAAVIVTHESLAAELPESDARQLHLDALDLTTEADP
CCCEEECCCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHCCCCCCCEEEEEHEECCCCCCC
IRAGAAEDLAYLIYTSGSTGLPKGVMVRHRNVANFFTAMDARIPHQPGDAWLAVTSLSFD
CCCCCCCCEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCEEEEEEECCH
ISVLELFWTLARGFKLVLSSDESRLQLANGPIGLSDRKMDFNLYYWGNDDGAGEKKYELL
HHHHHHHHHHHHCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCCHHHHHH
LEGAKFADAHGFNAVWTPERHFHAFGGPYPNPSVTGAAVAAVTRNIGVRAGSCVAPLHHP
HCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCH
ARIAEEWAVIDNLTGGRAGIGFASGWQPDDFILRPENTPPANKPALFEALQTVRKLWRGE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCC
EVAFPRADGGQHSVVTQPRPVSEELAVWVTTAGNPETWREAGRVGANVLTHLLGQSIDEV
CEECCCCCCCCCCEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHHH
GDKIALYHAALREAGYDPADFTVTLMLHTYLAETREAAREVAREPMKDYLRSAAGLIKQY
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWAFPAFKRPKGVDNPFEMDLGSLSSEELEAILDFAFERYFEESGLFGTVDDAVARVEDL
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
KRIGVDEVACLIDYGIAPHVVLEGLKPLAEVLRRSNRVQELANDDFSLAAQIVRHGVTHM
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
QCTPSMARMIASDADASPALGRLRHLLVGGEALPGDLVAALREQTRATLHNMYGPTETTI
EECHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
WSTVETLERAPTGIAPIGTPVANNSVYVLDAKGQLAPVGAAGELYIGGAGVTAGYWRRDA
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCCCCCHHHHHC
LTAERFPDDPFLSGQKMYRTGDLVRWREDGKLDFLGRTDHQVKIRGQRIELGEIETALTA
CCHHCCCCCCCCCCCCEECCCCEEEECCCCCEEEECCCCCEEEEECCEEEHHHHHHHHHH
VEGVTAAVVIPRKVGSDERLVGYVTASGVFSETEAKAQLSRQLAGAMVPSHIVVLEAFPL
HHCCEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
TPNKKIDRKALPDPTPSRQEAHVISAEPQSPVQQKISEIWKALLGVPAVGKSDNFFALGG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
HSLLAVQAHRDIRSALEVERLSITDIFRFPTLDGLASHLEHLQTGDTTVAETSPAAPAGR
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCC
ADTMSKRRAMRANRKARSG
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TISTVVIGNESLLIGCCEALLARGHDIRAVVSTDAEITSWAASKGLNTHSKPLEIDIEF
EEEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEEEEH
DWLLSIANLQVLPEAVISKARLGAVNFHDGPLPDRAGLNTPNWAILEGAEEHGITWHLIE
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEEECCHHCCCEEEEEE
GGVDEGDILAQRRFAIAPDETAFSLNSKCYGAALDSFGEVLEQLESGALERTPQDLSHRR
CCCCCCHHHHHCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHH
YHARKDRPDAAGFLRFDRNRDTLLCLVRGLDMGGYWNPLTTAKIRLPGQVAAVGAAQATE
HHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCEEECCCCCCCC
GEGIPGEVLAVSANALTVACADGAIELRDLKTLSGGALQPSALLEVGDVLPTLSDQEVEA
CCCCCCCEEEEECCEEEEEECCCCEEEEHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
LNAAAQTCQKAEPYWRRSLAEMLPLPVPLQGAELDVEATADIQLPTDCAPQTLMAAMLAW
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEECEEEEECEECCCCCCHHHHHHHHHHH
LLQSLGETAGSIALSLPDLQTSDDLGVLSNWVPLSAEIDEKIKTVEARAAEVLDRLDNMG
HHHHHHHCCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GFATDLILRAPEVTIETPPEVALCLGTNLAPAQAKLALIQSDSRLQLRSCQLSPEALSML
CHHHHHHEECCCCEECCCCCEEEEECCCCCCCHHEEEEEECCCCEEEHHCCCCHHHHHHH
AARLQCLLNTLPEDGAATLSTLPMLPDSERTRLIETWNDTGCDYPTDQTIHAAFEAQVAR
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHEEECCCCCCCCCCCCCHHHHHHHHHHHC
TPDAIAVVFEDQQLTYRALNQRADALARHLHDLGAKPGSHVGVYLRRSMDLVIATLGILK
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHH
AGAAYVPLDPTYPADRIAHYITDSQAAVIVTHESLAAELPESDARQLHLDALDLTTEADP
CCCEEECCCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHCCCCCCCEEEEEHEECCCCCCC
IRAGAAEDLAYLIYTSGSTGLPKGVMVRHRNVANFFTAMDARIPHQPGDAWLAVTSLSFD
CCCCCCCCEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCEEEEEEECCH
ISVLELFWTLARGFKLVLSSDESRLQLANGPIGLSDRKMDFNLYYWGNDDGAGEKKYELL
HHHHHHHHHHHHCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCCHHHHHH
LEGAKFADAHGFNAVWTPERHFHAFGGPYPNPSVTGAAVAAVTRNIGVRAGSCVAPLHHP
HCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCCH
ARIAEEWAVIDNLTGGRAGIGFASGWQPDDFILRPENTPPANKPALFEALQTVRKLWRGE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCC
EVAFPRADGGQHSVVTQPRPVSEELAVWVTTAGNPETWREAGRVGANVLTHLLGQSIDEV
CEECCCCCCCCCCEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHHH
GDKIALYHAALREAGYDPADFTVTLMLHTYLAETREAAREVAREPMKDYLRSAAGLIKQY
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWAFPAFKRPKGVDNPFEMDLGSLSSEELEAILDFAFERYFEESGLFGTVDDAVARVEDL
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
KRIGVDEVACLIDYGIAPHVVLEGLKPLAEVLRRSNRVQELANDDFSLAAQIVRHGVTHM
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
QCTPSMARMIASDADASPALGRLRHLLVGGEALPGDLVAALREQTRATLHNMYGPTETTI
EECHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
WSTVETLERAPTGIAPIGTPVANNSVYVLDAKGQLAPVGAAGELYIGGAGVTAGYWRRDA
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCCCCCHHHHHC
LTAERFPDDPFLSGQKMYRTGDLVRWREDGKLDFLGRTDHQVKIRGQRIELGEIETALTA
CCHHCCCCCCCCCCCCEECCCCEEEECCCCCEEEECCCCCEEEEECCEEEHHHHHHHHHH
VEGVTAAVVIPRKVGSDERLVGYVTASGVFSETEAKAQLSRQLAGAMVPSHIVVLEAFPL
HHCCEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
TPNKKIDRKALPDPTPSRQEAHVISAEPQSPVQQKISEIWKALLGVPAVGKSDNFFALGG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
HSLLAVQAHRDIRSALEVERLSITDIFRFPTLDGLASHLEHLQTGDTTVAETSPAAPAGR
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCC
ADTMSKRRAMRANRKARSG
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]