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The map label for this gene is ruvC [H]

Identifier: 99082213

GI number: 99082213

Start: 2493554

End: 2494120

Strand: Reverse

Name: ruvC [H]

Synonym: TM1040_2373

Alternate gene names: 99082213

Gene position: 2494120-2493554 (Counterclockwise)

Preceding gene: 99082215

Following gene: 99082212

Centisome position: 77.92

GC content: 58.02

Gene sequence:

>567_bases
ATGTGTTCGCGTTTTGTGCTAGTGCTGGCCTCCAAGCAGACAATAAATAATCAAAGATCGGGCGGCGGAATGCGCATATT
GGGAATCGATCCGGGGCTTCGGACCCTTGGATGGGGGGTGATCGAATCAAATGGCGCCCGTCTCAGCCATGTCGCTAATG
GCCTGTGCCACTCTGATGGGGATGACCTTGGCGAACGGCTACTGTCGCTGCACAATCAGGTTACGGAAATCATCGACGCC
TATCGACCGGATCAGGCTGCCATTGAGCAGACTTTTGTCAACAAGGATGGCGCGGGAACGCTCAAGCTAGGTCAGGCGCG
TGGTGTCGCCTTGCTGACCTTGGCCAAAGCAGGTCTGCCGACGGGGGAATATGCGCCGAACCGCGTGAAGAAAACCGTGG
TTGGGGTCGGGCATGCCGAAAAGGAACAGGTTCTGCATATGGTGAAGCTGCAGCTGCCGGGTTGTGCGCCCAGGGGCGCG
GATGCGGCTGATGCTCTGGCGATTGCGATCTGTCACGCCTATTACGGAGGCAGCAACCAGCGGCAACTCAAAGAGGTGGG
CGCATGA

Upstream 100 bases:

>100_bases
GCATTTGTCTCAAAAATTGCCCCGTATGGGGCGTTTTGTGCTAGGTGCCGCGCGTGCATTGTGGCTCTGACACAAATGCG
TGAGGCGTGAATTCGATTGG

Downstream 100 bases:

>100_bases
TCGGCAAATTGACCGGGCGTCTGGATTACAAGACTCCGGACCATGTGATGATCGACGTGCGCGGCGTCGGTTATATCGTC
TACTGCTCGGATCGCACCTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MCSRFVLVLASKQTINNQRSGGGMRILGIDPGLRTLGWGVIESNGARLSHVANGLCHSDGDDLGERLLSLHNQVTEIIDA
YRPDQAAIEQTFVNKDGAGTLKLGQARGVALLTLAKAGLPTGEYAPNRVKKTVVGVGHAEKEQVLHMVKLQLPGCAPRGA
DAADALAIAICHAYYGGSNQRQLKEVGA

Sequences:

>Translated_188_residues
MCSRFVLVLASKQTINNQRSGGGMRILGIDPGLRTLGWGVIESNGARLSHVANGLCHSDGDDLGERLLSLHNQVTEIIDA
YRPDQAAIEQTFVNKDGAGTLKLGQARGVALLTLAKAGLPTGEYAPNRVKKTVVGVGHAEKEQVLHMVKLQLPGCAPRGA
DAADALAIAICHAYYGGSNQRQLKEVGA
>Mature_188_residues
MCSRFVLVLASKQTINNQRSGGGMRILGIDPGLRTLGWGVIESNGARLSHVANGLCHSDGDDLGERLLSLHNQVTEIIDA
YRPDQAAIEQTFVNKDGAGTLKLGQARGVALLTLAKAGLPTGEYAPNRVKKTVVGVGHAEKEQVLHMVKLQLPGCAPRGA
DAADALAIAICHAYYGGSNQRQLKEVGA

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=162, Percent_Identity=47.5308641975309, Blast_Score=127, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 19832; Mature: 19832

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSRFVLVLASKQTINNQRSGGGMRILGIDPGLRTLGWGVIESNGARLSHVANGLCHSDG
CCCCEEEEEECCHHHCCCCCCCCEEEEEECCCHHHHCCCEEECCCCCHHHHHHCCCCCCC
DDLGERLLSLHNQVTEIIDAYRPDQAAIEQTFVNKDGAGTLKLGQARGVALLTLAKAGLP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEEEHHCCCC
TGEYAPNRVKKTVVGVGHAEKEQVLHMVKLQLPGCAPRGADAADALAIAICHAYYGGSNQ
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
RQLKEVGA
HHHHHHCC
>Mature Secondary Structure
MCSRFVLVLASKQTINNQRSGGGMRILGIDPGLRTLGWGVIESNGARLSHVANGLCHSDG
CCCCEEEEEECCHHHCCCCCCCCEEEEEECCCHHHHCCCEEECCCCCHHHHHHCCCCCCC
DDLGERLLSLHNQVTEIIDAYRPDQAAIEQTFVNKDGAGTLKLGQARGVALLTLAKAGLP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCEEEEEEHHCCCC
TGEYAPNRVKKTVVGVGHAEKEQVLHMVKLQLPGCAPRGADAADALAIAICHAYYGGSNQ
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
RQLKEVGA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA