BacMap

Definition	Ruegeria sp. TM1040, complete genome.
Accession	NC_008044
Length	3,200,938

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The map label for this gene is fabG [H]

Identifier: 99082025

GI number: 99082025

Start: 2294846

End: 2295598

Strand: Reverse

Name: fabG [H]

Synonym: TM1040_2185

Alternate gene names: 99082025

Gene position: 2295598-2294846 (Counterclockwise)

Preceding gene: 99082026

Following gene: 99082023

Centisome position: 71.72

GC content: 66.93

Gene sequence:

>753_bases
ATGCGCGTTCTGGTGACGGCGGGCGCGTCCGGTATCGGGCGCGCCATGGCAGAGGGCTTTGTCGCGACGGGCGCCGAAGT
CTGGGTTTCCGATGTGGATCGCGACGCCCTGGCCGCGCTGCCCGACGGGTGGAACGCGCGGCAGGTCGATGCCACCGACG
AGGTCGCGATGCGCGCGCTCTTTGCCGAGATTGCGCAGGCAGGCGGGCTTGATGTGCTCTGCGCCAATGCTGGCGTGGCC
GGGCCGACCGCCTTGGTGGAAGACATCCAGCTGGAGGACTGGCGCGCCTGTGTCAGCGTCAACCTCGAGGGTGCCTTTCT
GGCGGCGAAATACGCGGCACCGCTCATGAAAGCGGCCGGGCAGGGCAGCATCGTGCTTACATCGTCTACGGCGGGGATCT
ACGGCTATCCCAATCGCGCGCCCTATGCGGCCGCGAAATGGGCTGTGATTGGCCTGATGAAAACCCTCGCGATGGAGCTC
GGCCCCTTTGGTATCCGCGCCAATGCGATCTGCCCCGGCGCGGTCGAGGGGCCGCGCATGGAGGGCGTTCTGGCGCGCGA
GGCGGCACTCAAAGGCATGAGCCGCGATGCGGTCCACGAGGGCTATGCCGCGGGCACGTCTATGCGCACCTGGGTCACGG
CTGAGGATGTGGCCAACATGGCGGTGTTCCTTGGCTCCGAAGCTTCGCGGCGCATCTCCGGTCAGGTCATTGCGGTGGAT
GGCCACACGGAAAACCCGGATCCGAAGGTATAG

Upstream 100 bases:

>100_bases
CGGCCGCGCATATCGAGGCCAATCTTGTGAAGCTCGCCGAGGCACATGCGGCGTTGCCCGCACCCGAAGGGCTGGGTCGC
GCCATCGGTGCGCCTCGCTA

Downstream 100 bases:

>100_bases
GACCGGCGTCAAACACGGAGCGTTTTGGTCACTCGGATCAGGTGCCGCCAGCCGCCCGGATGGCGCAGCGCTACGTCGCC
ACCCCGATCTGTGCGCGCAG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRVLVTAGASGIGRAMAEGFVATGAEVWVSDVDRDALAALPDGWNARQVDATDEVAMRALFAEIAQAGGLDVLCANAGVA
GPTALVEDIQLEDWRACVSVNLEGAFLAAKYAAPLMKAAGQGSIVLTSSTAGIYGYPNRAPYAAAKWAVIGLMKTLAMEL
GPFGIRANAICPGAVEGPRMEGVLAREAALKGMSRDAVHEGYAAGTSMRTWVTAEDVANMAVFLGSEASRRISGQVIAVD
GHTENPDPKV

Sequences:

>Translated_250_residues
MRVLVTAGASGIGRAMAEGFVATGAEVWVSDVDRDALAALPDGWNARQVDATDEVAMRALFAEIAQAGGLDVLCANAGVA
GPTALVEDIQLEDWRACVSVNLEGAFLAAKYAAPLMKAAGQGSIVLTSSTAGIYGYPNRAPYAAAKWAVIGLMKTLAMEL
GPFGIRANAICPGAVEGPRMEGVLAREAALKGMSRDAVHEGYAAGTSMRTWVTAEDVANMAVFLGSEASRRISGQVIAVD
GHTENPDPKV
>Mature_250_residues
MRVLVTAGASGIGRAMAEGFVATGAEVWVSDVDRDALAALPDGWNARQVDATDEVAMRALFAEIAQAGGLDVLCANAGVA
GPTALVEDIQLEDWRACVSVNLEGAFLAAKYAAPLMKAAGQGSIVLTSSTAGIYGYPNRAPYAAAKWAVIGLMKTLAMEL
GPFGIRANAICPGAVEGPRMEGVLAREAALKGMSRDAVHEGYAAGTSMRTWVTAEDVANMAVFLGSEASRRISGQVIAVD
GHTENPDPKV

Specific function: Sorbitol metabolism. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=29.4354838709677, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI66933014, Length=226, Percent_Identity=30.9734513274336, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.5490196078431, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI59889578, Length=214, Percent_Identity=34.1121495327103, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=31.3432835820896, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI4504505, Length=214, Percent_Identity=33.1775700934579, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI126723191, Length=178, Percent_Identity=33.7078651685393, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=30.5825242718447, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=36.8932038834951, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI223718074, Length=217, Percent_Identity=31.3364055299539, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI209862901, Length=207, Percent_Identity=31.8840579710145, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19923983, Length=207, Percent_Identity=31.8840579710145, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=25.9842519685039, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789057, Length=250, Percent_Identity=30.4, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=31.9838056680162, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=31.2252964426877, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=30.0813008130081, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=32.1285140562249, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=27.7551020408163, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.4900398406374, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=26.8774703557312, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=27.6422764227642, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=28.1124497991968, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787820, Length=188, Percent_Identity=28.1914893617021, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI2367175, Length=187, Percent_Identity=33.6898395721925, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=32.2448979591837, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=29.2490118577075, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=27.710843373494, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=28.8973384030418, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=31.2820512820513, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=194, Percent_Identity=32.4742268041237, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=28.8973384030418, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=27.8884462151394, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.1746031746032, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=187, Percent_Identity=31.0160427807487, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=25.8964143426295, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=186, Percent_Identity=26.8817204301075, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=29.4339622641509, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=28.030303030303, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=262, Percent_Identity=27.8625954198473, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=29.4820717131474, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=30.3643724696356, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=29.296875, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859837, Length=202, Percent_Identity=33.6633663366337, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356301, Length=245, Percent_Identity=26.1224489795918, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571526, Length=183, Percent_Identity=29.5081967213115, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=193, Percent_Identity=33.6787564766839, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=181, Percent_Identity=31.4917127071823, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644337, Length=182, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643142, Length=177, Percent_Identity=31.638418079096, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=28.2868525896414, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25837; Mature: 25837

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVTAGASGIGRAMAEGFVATGAEVWVSDVDRDALAALPDGWNARQVDATDEVAMRAL
CEEEEECCCCHHHHHHHHHHHHCCHHHHEHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
FAEIAQAGGLDVLCANAGVAGPTALVEDIQLEDWRACVSVNLEGAFLAAKYAAPLMKAAG
HHHHHHCCCCEEEEECCCCCCCHHHHHHCCHHCCEEEEEECCCCHHHHHHHHHHHHHHCC
QGSIVLTSSTAGIYGYPNRAPYAAAKWAVIGLMKTLAMELGPFGIRANAICPGAVEGPRM
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
EGVLAREAALKGMSRDAVHEGYAAGTSMRTWVTAEDVANMAVFLGSEASRRISGQVIAVD
CHHHHHHHHHCCCCHHHHHHCHHCCCCEEEEEEHHHHHHHHHEECCCCCCCCCCEEEEEE
GHTENPDPKV
CCCCCCCCCC
>Mature Secondary Structure
MRVLVTAGASGIGRAMAEGFVATGAEVWVSDVDRDALAALPDGWNARQVDATDEVAMRAL
CEEEEECCCCHHHHHHHHHHHHCCHHHHEHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHH
FAEIAQAGGLDVLCANAGVAGPTALVEDIQLEDWRACVSVNLEGAFLAAKYAAPLMKAAG
HHHHHHCCCCEEEEECCCCCCCHHHHHHCCHHCCEEEEEECCCCHHHHHHHHHHHHHHCC
QGSIVLTSSTAGIYGYPNRAPYAAAKWAVIGLMKTLAMELGPFGIRANAICPGAVEGPRM
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCC
EGVLAREAALKGMSRDAVHEGYAAGTSMRTWVTAEDVANMAVFLGSEASRRISGQVIAVD
CHHHHHHHHHCCCCHHHHHHCHHCCCCEEEEEEHHHHHHHHHEECCCCCCCCCCEEEEEE
GHTENPDPKV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]