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The map label for this gene is 99082011

Identifier: 99082011

GI number: 99082011

Start: 2283726

End: 2285285

Strand: Reverse

Name: 99082011

Synonym: TM1040_2171

Alternate gene names: NA

Gene position: 2285285-2283726 (Counterclockwise)

Preceding gene: 99082012

Following gene: 99082010

Centisome position: 71.39

GC content: 60.45

Gene sequence:

>1560_bases
ATGTCGCAGACACAAGCGCGCCGACGCCGGGGAGGAGGCCGGGCCGGTGCAGCCGCCCGTCGGGGAGCCGCCACTTTGGA
GCAGATGCCATGGAAGCCTCCGGTCAATATTGACCGCCCGGTCGAGCCGCTCACCGCAGAGGGTATTGCCGCAATCCATG
ATGGCGCGATGCGCATTCTCGAGGAGATCGGCGTCGAGTTCCTGAACGACGAAGCGCTTGAGATCTTCAAGGAGGCGGGG
CTCAAGGTGGATGGCGCTTTGGTGCGCATGGACCGCGAGTTTGTGATGGAGATGGTGGGCAAGGTCCCCTCGGAGTTCAC
CCTTACGCCGCGCAACCCAGAGCGCGCCATTCGCATCGGCGGCAATTCGATCGTCTTTGGCAATGTGTCCTCGCCGCCGA
ACTATTGGGATATGGACCTGAACAAGAAGGTCCCCGGCACCCGTGAACACTGCCAGAACCTGCTGAAATTGACGCAGTAT
TTCAACTGCATCCATTTTGCGGGGGGCTATCCGGTGGAGCCTGTCGATCTCCATGCCTCGATCCGTCACCTCGATGTGCT
TTATGACAAGCTCACGCTCACCGACAAGGTGATGCATGCCTATTCGCTCGGCAAAGAGCGGGTCGAGGACGTGATGGAGA
TGGTGCGCATCGCGGGTGGTCTGAGCCATGAGGAATTCGACTCCCAACCGCACATGTACACCAACATCAACTCCACCTCG
CCCTTGAAGCATGACGAGCCGATGATTGATGGTGCGCTGAGGCTGGTGCGGCGGGGCCAACCCGTGATCGTGTCACCGTT
CACGCTGGCAGGCGCGATGGCTCCGGTCACCATGGCGGGGGCCGTGGCGCAGTCGCTGGCAGAGGCGCTCTGCGCCATTG
CCCTGTTCCAATATGTCCGCCCCGGCACGCCCTGCGCGATCGGAACGTTTACCTCCAATGTCGACATGAAGTCCGGAGCA
CCTGCATTTGGAACTCCTGAATATATGCGCGCGACTCAAATGACCGGGCAGATGGCACGATTTTACGGATTGCCGATGCG
GTCCTCCGGCGTTTGCGCGGCCAATGTGCCGGATGGGCAAGCCATGTGGGAGACGTCGAACTCGCTCTGGGCAGCGGTGC
AGTCGGGCACGAATATGGTCTACCACGCTGCGGGCTGGCTCGAAGGCGGGCTGATCGCCTCTCCAGAGAAATTCATCATG
GATTGCGAGGTCTTGCAGATGATCCAGCGCTACATGGACCCGGTCATCAATGCCACCGGCCCCGAGGAAATCGCGCTCGA
TGCGATCCGGGAGGTCGGAAATGATGGACATTTCTTCGGCATCCAGCACACGCAGGATCGTTATGCGACAGCCTTTTATC
AGCCGTTCCTGAGCGACTGGCACAATTATGAGGCTTGGGAGGCCGCGGGCGGAACCTGGACCGCGCAGCGAGCAAACGGT
CTCTTCAAGCAGATCATCAACGAATTCGAGGCTCCGACGCTTGATGAGGGCATTCGCGAAGAGCTGCAGGCCTTCGTCGC
CCGCCGGAAGGAAGAAGGCGGAGCCCCCACAGATTTTTAA

Upstream 100 bases:

>100_bases
AGGGCAAATGCGACATGAGGTGTCGGTATTGGACAGGTGTGTCTGGTGTCATCCGGCCCAATCTGGACGGGTAAAAATCC
GTCGCAGGAGAGGGAATCCC

Downstream 100 bases:

>100_bases
CCATTGTTACTCAATTGACGCGGCGCAAGCAATTTTACGCGCTTCCACAAGGGGAGCGGGCACTATGGGGTTGGAGCCTC
CATGGTGCTTACGGTATGAT

Product: trimethylamine methyltransferase

Products: NA

Alternate protein names: TMA methyltransferase [H]

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MSQTQARRRRGGGRAGAAARRGAATLEQMPWKPPVNIDRPVEPLTAEGIAAIHDGAMRILEEIGVEFLNDEALEIFKEAG
LKVDGALVRMDREFVMEMVGKVPSEFTLTPRNPERAIRIGGNSIVFGNVSSPPNYWDMDLNKKVPGTREHCQNLLKLTQY
FNCIHFAGGYPVEPVDLHASIRHLDVLYDKLTLTDKVMHAYSLGKERVEDVMEMVRIAGGLSHEEFDSQPHMYTNINSTS
PLKHDEPMIDGALRLVRRGQPVIVSPFTLAGAMAPVTMAGAVAQSLAEALCAIALFQYVRPGTPCAIGTFTSNVDMKSGA
PAFGTPEYMRATQMTGQMARFYGLPMRSSGVCAANVPDGQAMWETSNSLWAAVQSGTNMVYHAAGWLEGGLIASPEKFIM
DCEVLQMIQRYMDPVINATGPEEIALDAIREVGNDGHFFGIQHTQDRYATAFYQPFLSDWHNYEAWEAAGGTWTAQRANG
LFKQIINEFEAPTLDEGIREELQAFVARRKEEGGAPTDF

Sequences:

>Translated_519_residues
MSQTQARRRRGGGRAGAAARRGAATLEQMPWKPPVNIDRPVEPLTAEGIAAIHDGAMRILEEIGVEFLNDEALEIFKEAG
LKVDGALVRMDREFVMEMVGKVPSEFTLTPRNPERAIRIGGNSIVFGNVSSPPNYWDMDLNKKVPGTREHCQNLLKLTQY
FNCIHFAGGYPVEPVDLHASIRHLDVLYDKLTLTDKVMHAYSLGKERVEDVMEMVRIAGGLSHEEFDSQPHMYTNINSTS
PLKHDEPMIDGALRLVRRGQPVIVSPFTLAGAMAPVTMAGAVAQSLAEALCAIALFQYVRPGTPCAIGTFTSNVDMKSGA
PAFGTPEYMRATQMTGQMARFYGLPMRSSGVCAANVPDGQAMWETSNSLWAAVQSGTNMVYHAAGWLEGGLIASPEKFIM
DCEVLQMIQRYMDPVINATGPEEIALDAIREVGNDGHFFGIQHTQDRYATAFYQPFLSDWHNYEAWEAAGGTWTAQRANG
LFKQIINEFEAPTLDEGIREELQAFVARRKEEGGAPTDF
>Mature_518_residues
SQTQARRRRGGGRAGAAARRGAATLEQMPWKPPVNIDRPVEPLTAEGIAAIHDGAMRILEEIGVEFLNDEALEIFKEAGL
KVDGALVRMDREFVMEMVGKVPSEFTLTPRNPERAIRIGGNSIVFGNVSSPPNYWDMDLNKKVPGTREHCQNLLKLTQYF
NCIHFAGGYPVEPVDLHASIRHLDVLYDKLTLTDKVMHAYSLGKERVEDVMEMVRIAGGLSHEEFDSQPHMYTNINSTSP
LKHDEPMIDGALRLVRRGQPVIVSPFTLAGAMAPVTMAGAVAQSLAEALCAIALFQYVRPGTPCAIGTFTSNVDMKSGAP
AFGTPEYMRATQMTGQMARFYGLPMRSSGVCAANVPDGQAMWETSNSLWAAVQSGTNMVYHAAGWLEGGLIASPEKFIMD
CEVLQMIQRYMDPVINATGPEEIALDAIREVGNDGHFFGIQHTQDRYATAFYQPFLSDWHNYEAWEAAGGTWTAQRANGL
FKQIINEFEAPTLDEGIREELQAFVARRKEEGGAPTDF

Specific function: Catalyzes probably the transfer of a methyl group from trimethylamine to the corrinoid cofactor of mttC [H]

COG id: COG5598

COG function: function code H; Trimethylamine:corrinoid methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trimethylamine methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010426 [H]

Pfam domain/function: PF06253 MTTB [H]

EC number: NA

Molecular weight: Translated: 57221; Mature: 57090

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTQARRRRGGGRAGAAARRGAATLEQMPWKPPVNIDRPVEPLTAEGIAAIHDGAMRIL
CCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EEIGVEFLNDEALEIFKEAGLKVDGALVRMDREFVMEMVGKVPSEFTLTPRNPERAIRIG
HHHCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
GNSIVFGNVSSPPNYWDMDLNKKVPGTREHCQNLLKLTQYFNCIHFAGGYPVEPVDLHAS
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IRHLDVLYDKLTLTDKVMHAYSLGKERVEDVMEMVRIAGGLSHEEFDSQPHMYTNINSTS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCEEECCCCCC
PLKHDEPMIDGALRLVRRGQPVIVSPFTLAGAMAPVTMAGAVAQSLAEALCAIALFQYVR
CCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGTPCAIGTFTSNVDMKSGAPAFGTPEYMRATQMTGQMARFYGLPMRSSGVCAANVPDGQ
CCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
AMWETSNSLWAAVQSGTNMVYHAAGWLEGGLIASPEKFIMDCEVLQMIQRYMDPVINATG
HHHHCCCHHHHHHHCCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
PEEIALDAIREVGNDGHFFGIQHTQDRYATAFYQPFLSDWHNYEAWEAAGGTWTAQRANG
HHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCEEHHHHHH
LFKQIINEFEAPTLDEGIREELQAFVARRKEEGGAPTDF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SQTQARRRRGGGRAGAAARRGAATLEQMPWKPPVNIDRPVEPLTAEGIAAIHDGAMRIL
CCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EEIGVEFLNDEALEIFKEAGLKVDGALVRMDREFVMEMVGKVPSEFTLTPRNPERAIRIG
HHHCHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
GNSIVFGNVSSPPNYWDMDLNKKVPGTREHCQNLLKLTQYFNCIHFAGGYPVEPVDLHAS
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IRHLDVLYDKLTLTDKVMHAYSLGKERVEDVMEMVRIAGGLSHEEFDSQPHMYTNINSTS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCCCEEECCCCCC
PLKHDEPMIDGALRLVRRGQPVIVSPFTLAGAMAPVTMAGAVAQSLAEALCAIALFQYVR
CCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGTPCAIGTFTSNVDMKSGAPAFGTPEYMRATQMTGQMARFYGLPMRSSGVCAANVPDGQ
CCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
AMWETSNSLWAAVQSGTNMVYHAAGWLEGGLIASPEKFIMDCEVLQMIQRYMDPVINATG
HHHHCCCHHHHHHHCCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
PEEIALDAIREVGNDGHFFGIQHTQDRYATAFYQPFLSDWHNYEAWEAAGGTWTAQRANG
HHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCEEHHHHHH
LFKQIINEFEAPTLDEGIREELQAFVARRKEEGGAPTDF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA