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The map label for this gene is ribH [H]

Identifier: 99081968

GI number: 99081968

Start: 2233505

End: 2234029

Strand: Reverse

Name: ribH [H]

Synonym: TM1040_2128

Alternate gene names: 99081968

Gene position: 2234029-2233505 (Counterclockwise)

Preceding gene: 99081969

Following gene: 99081967

Centisome position: 69.79

GC content: 59.81

Gene sequence:

>525_bases
ATGGCCGGACAAGAAAGCCACTACATCCTGCCGCGCCCTGAGTTTGACAAGCCGGTAAAGCTGCTCATCGTGGTCTCGCC
CTATTACAAGGACATCGCTGATAATATGGTTGCCGGTGCCGTGGCCGAAATCGAAGCCGTCGGCGGAACCTATGAGGTTG
TTGAGGTCCCGGGTGCGCTGGAAATCCCCACTGCGATCGGGATCTCGGATCGGGCCTCGAACTTTGACGGCTATGTTGCG
CTGGGCTGCGTGATCCGGGGCGAAACAACCCATTACGATACGGTCTGCAATGACAGTTCGCGCGCGATCCAACTGCTTGG
GCTACAGGGGCTTTGCATCGGCAACGGTATTCTGACGGTAGAAAACCGAAAACAGGCCGAAGTGCGCGCGGACCCTGAGG
ATCAAAACAAGGGCGGCGGCGCGGCAGCTGCGGCCTTGCATCTGATCGCGCTCGCGCGTAAGTGGGGCGCCCAGACCAAG
GGAGTTGGGTTTAAACCTGCCTCCGACTCGTACCGGCTCGCCTGA

Upstream 100 bases:

>100_bases
ACTCGCCGCAAACCAAATATGTTGGGCTGGATGCCTATGGGCTGTCGATTGTCGGCACCCGTCCCATCCTGTCCCGAGAC
AGCTAAAGGAGTCCTCCGCC

Downstream 100 bases:

>100_bases
TTTCAACAACGGATCCCTCGCTCATGACCTCCAAAGACGCCCCGAAACCGGGAAAGAACAAGACGCAGGCGCGCTCTGCC
GCGCGTCTTTATGCGGTGCA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MAGQESHYILPRPEFDKPVKLLIVVSPYYKDIADNMVAGAVAEIEAVGGTYEVVEVPGALEIPTAIGISDRASNFDGYVA
LGCVIRGETTHYDTVCNDSSRAIQLLGLQGLCIGNGILTVENRKQAEVRADPEDQNKGGGAAAAALHLIALARKWGAQTK
GVGFKPASDSYRLA

Sequences:

>Translated_174_residues
MAGQESHYILPRPEFDKPVKLLIVVSPYYKDIADNMVAGAVAEIEAVGGTYEVVEVPGALEIPTAIGISDRASNFDGYVA
LGCVIRGETTHYDTVCNDSSRAIQLLGLQGLCIGNGILTVENRKQAEVRADPEDQNKGGGAAAAALHLIALARKWGAQTK
GVGFKPASDSYRLA
>Mature_173_residues
AGQESHYILPRPEFDKPVKLLIVVSPYYKDIADNMVAGAVAEIEAVGGTYEVVEVPGALEIPTAIGISDRASNFDGYVAL
GCVIRGETTHYDTVCNDSSRAIQLLGLQGLCIGNGILTVENRKQAEVRADPEDQNKGGGAAAAALHLIALARKWGAQTKG
VGFKPASDSYRLA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=135, Percent_Identity=32.5925925925926, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 18400; Mature: 18269

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQESHYILPRPEFDKPVKLLIVVSPYYKDIADNMVAGAVAEIEAVGGTYEVVEVPGAL
CCCCCCCEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCE
EIPTAIGISDRASNFDGYVALGCVIRGETTHYDTVCNDSSRAIQLLGLQGLCIGNGILTV
ECCEECCCCCCCCCCCCEEEEEEEEECCCCCCCCEECCCCCEEEEECCCCEEECCCEEEE
ENRKQAEVRADPEDQNKGGGAAAAALHLIALARKWGAQTKGVGFKPASDSYRLA
CCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGQESHYILPRPEFDKPVKLLIVVSPYYKDIADNMVAGAVAEIEAVGGTYEVVEVPGAL
CCCCCCEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCE
EIPTAIGISDRASNFDGYVALGCVIRGETTHYDTVCNDSSRAIQLLGLQGLCIGNGILTV
ECCEECCCCCCCCCCCCEEEEEEEEECCCCCCCCEECCCCCEEEEECCCCEEECCCEEEE
ENRKQAEVRADPEDQNKGGGAAAAALHLIALARKWGAQTKGVGFKPASDSYRLA
CCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA