Click here to switch to the map view.

The map label for this gene is siaT [H]

Identifier: 99081430

GI number: 99081430

Start: 1700175

End: 1701434

Strand: Reverse

Name: siaT [H]

Synonym: TM1040_1589

Alternate gene names: 99081430

Gene position: 1701434-1700175 (Counterclockwise)

Preceding gene: 99081431

Following gene: 99081429

Centisome position: 53.15

GC content: 58.89

Gene sequence:

>1260_bases
ATGACGCCTTTGATCTTTGCTTTCAAACTCTTGATCGCGGTGCCGGTGGCCTTGGTTCTGGCGCTCACGGCCATCTGGTA
CATCTGGGAGAGCGGCAACACGGTCCTCTATGACAGTTTTGCGCAAAAGATGTTCTCCGGGCTAGAGAGTTACGGCCTGC
TGGCGATCCCGCTGTTCATGCTGACGGGGGAGATGATGAACGAAGGCGGCATGACCCGCCGCTTGATCAATGCGGCTCGG
GTCTTTGTCGGCGGGTTTCGCGGTGGGCTCGCCTATATCAACCTGCTGACCAATATGTTCATGGCGGCGATCATCGGATC
GGCCACAGCGCAGATCGCGGTGATGGCCCGTGCGATGACGCCAGAGATGGAAAAAGAGGGGTATGACACGGGCTTTGCCG
CTGCCACGACAGCGGCGGGCGGGTTGCTTGCGCCGGTCATCCCGCCGTCGATGATGTTCGTGATCTTCGGCGTACTGGCC
CAGGTTCCGATTGGCGAGATGTTTCTTGCAGGCCTCATTCCGGGGATGATGCTTGCAGGGGCCTTTGCGCTGGTGATCTT
CGGGATCGGTGTCGCCACAGGCTTTCCAAAGGGCAGCTGGTTCACCGCGCCAGAGGCGTTCTCGGCGCTTCTATATTGCT
TGCCCGCAGCGCTGATCCCCTGTGCGATCATCGGCGGTGTGGTGTTTGGGATTGCAACCCCGACCGAGAGCGCTGCAATC
GCCTCTCTGCTGGCCTTTGGGATGGGGTGGCTGGTCTATGGCGAACTGAAGCCTGCGGCCCTCTTTGCGATGTTCCGTCG
CACTGCCATCAACGCCTCGATGATCATCTTCATGATCGCCTGTGCCAATGTCTTTGGCTGGGTCATCATCTACGAGGCCC
TGCCACAAAAGCTCGCGGCGCTGATCACCTCGATCACCAGTGACCCGTTTCTGTTTCTGCTGATCGTCAATCTGATCCTG
CTGCTGATCGGGATGCTGGTGGATGGGATCGCCGCCGTGATCCTGATCTCGCCCATCTTGTTGCCGATCGCGGTAAACCA
CTATGACATCAGCGCCCATCAATTTGGTGTCGTCATGTGCCTGAACCTCGTGCTGGGCTTGCTGACACCGCCCGTTGGGG
TCGGGCTTTATATTGCGTCTTCCATGAGTGGCGCCACGCCCGGCCAGATCCTGCGCTCCCTCTGGCCATTCCTTTTGGCG
GTAGCGCTAATCCTTGTCCTATTGAGCCGGTTTCCTGTGTTGTCGACCGCGTTTCTATAG

Upstream 100 bases:

>100_bases
ATTGGGTCTGGTCCGTGATGTGGGTCTTCGCGCTCGGGATGACACTGCACAGTTTTGCAAATCTGATCGGGCAGGGTGCC
AACCCAGAGGATGACCGTTC

Downstream 100 bases:

>100_bases
TTCAGGTGATCTAAATGGGGCGCAAATGGCGCTGAATTCATTCAAATTGAAATTACTAAATGGGCTCGTATGAGATGTTT
TTGTTGCGCGTACTGGCCAA

Product: TRAP dicarboxylate transporter- DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTPLIFAFKLLIAVPVALVLALTAIWYIWESGNTVLYDSFAQKMFSGLESYGLLAIPLFMLTGEMMNEGGMTRRLINAAR
VFVGGFRGGLAYINLLTNMFMAAIIGSATAQIAVMARAMTPEMEKEGYDTGFAAATTAAGGLLAPVIPPSMMFVIFGVLA
QVPIGEMFLAGLIPGMMLAGAFALVIFGIGVATGFPKGSWFTAPEAFSALLYCLPAALIPCAIIGGVVFGIATPTESAAI
ASLLAFGMGWLVYGELKPAALFAMFRRTAINASMIIFMIACANVFGWVIIYEALPQKLAALITSITSDPFLFLLIVNLIL
LLIGMLVDGIAAVILISPILLPIAVNHYDISAHQFGVVMCLNLVLGLLTPPVGVGLYIASSMSGATPGQILRSLWPFLLA
VALILVLLSRFPVLSTAFL

Sequences:

>Translated_419_residues
MTPLIFAFKLLIAVPVALVLALTAIWYIWESGNTVLYDSFAQKMFSGLESYGLLAIPLFMLTGEMMNEGGMTRRLINAAR
VFVGGFRGGLAYINLLTNMFMAAIIGSATAQIAVMARAMTPEMEKEGYDTGFAAATTAAGGLLAPVIPPSMMFVIFGVLA
QVPIGEMFLAGLIPGMMLAGAFALVIFGIGVATGFPKGSWFTAPEAFSALLYCLPAALIPCAIIGGVVFGIATPTESAAI
ASLLAFGMGWLVYGELKPAALFAMFRRTAINASMIIFMIACANVFGWVIIYEALPQKLAALITSITSDPFLFLLIVNLIL
LLIGMLVDGIAAVILISPILLPIAVNHYDISAHQFGVVMCLNLVLGLLTPPVGVGLYIASSMSGATPGQILRSLWPFLLA
VALILVLLSRFPVLSTAFL
>Mature_418_residues
TPLIFAFKLLIAVPVALVLALTAIWYIWESGNTVLYDSFAQKMFSGLESYGLLAIPLFMLTGEMMNEGGMTRRLINAARV
FVGGFRGGLAYINLLTNMFMAAIIGSATAQIAVMARAMTPEMEKEGYDTGFAAATTAAGGLLAPVIPPSMMFVIFGVLAQ
VPIGEMFLAGLIPGMMLAGAFALVIFGIGVATGFPKGSWFTAPEAFSALLYCLPAALIPCAIIGGVVFGIATPTESAAIA
SLLAFGMGWLVYGELKPAALFAMFRRTAINASMIIFMIACANVFGWVIIYEALPQKLAALITSITSDPFLFLLIVNLILL
LIGMLVDGIAAVILISPILLPIAVNHYDISAHQFGVVMCLNLVLGLLTPPVGVGLYIASSMSGATPGQILRSLWPFLLAV
ALILVLLSRFPVLSTAFL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=403, Percent_Identity=32.7543424317618, Blast_Score=176, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44280; Mature: 44149

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLIFAFKLLIAVPVALVLALTAIWYIWESGNTVLYDSFAQKMFSGLESYGLLAIPLFM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHH
LTGEMMNEGGMTRRLINAARVFVGGFRGGLAYINLLTNMFMAAIIGSATAQIAVMARAMT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEMEKEGYDTGFAAATTAAGGLLAPVIPPSMMFVIFGVLAQVPIGEMFLAGLIPGMMLAG
CCHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AFALVIFGIGVATGFPKGSWFTAPEAFSALLYCLPAALIPCAIIGGVVFGIATPTESAAI
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ASLLAFGMGWLVYGELKPAALFAMFRRTAINASMIIFMIACANVFGWVIIYEALPQKLAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITSITSDPFLFLLIVNLILLLIGMLVDGIAAVILISPILLPIAVNHYDISAHQFGVVMC
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LNLVLGLLTPPVGVGLYIASSMSGATPGQILRSLWPFLLAVALILVLLSRFPVLSTAFL
HHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
TPLIFAFKLLIAVPVALVLALTAIWYIWESGNTVLYDSFAQKMFSGLESYGLLAIPLFM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHH
LTGEMMNEGGMTRRLINAARVFVGGFRGGLAYINLLTNMFMAAIIGSATAQIAVMARAMT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEMEKEGYDTGFAAATTAAGGLLAPVIPPSMMFVIFGVLAQVPIGEMFLAGLIPGMMLAG
CCHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AFALVIFGIGVATGFPKGSWFTAPEAFSALLYCLPAALIPCAIIGGVVFGIATPTESAAI
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ASLLAFGMGWLVYGELKPAALFAMFRRTAINASMIIFMIACANVFGWVIIYEALPQKLAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITSITSDPFLFLLIVNLILLLIGMLVDGIAAVILISPILLPIAVNHYDISAHQFGVVMC
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LNLVLGLLTPPVGVGLYIASSMSGATPGQILRSLWPFLLAVALILVLLSRFPVLSTAFL
HHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]