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The map label for this gene is cdd [H]

Identifier: 99081413

GI number: 99081413

Start: 1680082

End: 1680576

Strand: Reverse

Name: cdd [H]

Synonym: TM1040_1572

Alternate gene names: 99081413

Gene position: 1680576-1680082 (Counterclockwise)

Preceding gene: 99081416

Following gene: 99081412

Centisome position: 52.5

GC content: 63.23

Gene sequence:

>495_bases
ATGCCACAAGGCCCGAGGCCCCACGCGCTGGCGCAGGATCGTCAGCCACGGCCCCCTGCGAGGACGGAGATCATTATGCC
TGCATCAGACACCGATACTATTCATCCATTGCGCGCAGCCGCTGCTACGGTGCGCCAGAATGCCCATGCGCCCTATTCGA
ACTTCAAGGTGGGCGCGGCGATCCGGGCCAAATCCGGCACGGTCTATGTGGGCTGCAATGTCGAAAACGTGGCCTATCCC
GAAGGCACCTGTGCCGAGGCCGGTGCGATTGCGGCGATGGTGGCGGCCGGTGAAACTGAACTTCTTGAGGCCTATGTGAT
CGCCGATTGCCCAAGCCCGGTGCCGCCCTGCGGCGGCTGCCGTCAGAAGCTCAAGGAATTCGGCGCTGCCGAGGTCGCGG
TGACCCTTGCAACCACCGATGGCGTCGAAATGCAGACCACGATTGGTGATCTGCTGCCTGGCGCGTTTGACGCAGGCCAT
ATGGAGCGGAGCTGA

Upstream 100 bases:

>100_bases
CCAGAAGGCTTTGGTCTTGTTGATTGAGGGAGGGTGCCGCGAGATGACATTTGACCATCCGATCAAAACGGGCAAAGACT
GGGACAACAGGACCACACGA

Downstream 100 bases:

>100_bases
GGGCATGGATGCGCGCGCGGTCATTGCCCGGTTAAGGCAGAAACACACCCCAAGCACCGAGGAGCTGCGCTGGTTTGCCG
AGGGGCTTGCCAGTGGCGCC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MPQGPRPHALAQDRQPRPPARTEIIMPASDTDTIHPLRAAAATVRQNAHAPYSNFKVGAAIRAKSGTVYVGCNVENVAYP
EGTCAEAGAIAAMVAAGETELLEAYVIADCPSPVPPCGGCRQKLKEFGAAEVAVTLATTDGVEMQTTIGDLLPGAFDAGH
MERS

Sequences:

>Translated_164_residues
MPQGPRPHALAQDRQPRPPARTEIIMPASDTDTIHPLRAAAATVRQNAHAPYSNFKVGAAIRAKSGTVYVGCNVENVAYP
EGTCAEAGAIAAMVAAGETELLEAYVIADCPSPVPPCGGCRQKLKEFGAAEVAVTLATTDGVEMQTTIGDLLPGAFDAGH
MERS
>Mature_163_residues
PQGPRPHALAQDRQPRPPARTEIIMPASDTDTIHPLRAAAATVRQNAHAPYSNFKVGAAIRAKSGTVYVGCNVENVAYPE
GTCAEAGAIAAMVAAGETELLEAYVIADCPSPVPPCGGCRQKLKEFGAAEVAVTLATTDGVEMQTTIGDLLPGAFDAGHM
ERS

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=134, Percent_Identity=32.8358208955224, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540514, Length=128, Percent_Identity=42.1875, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551074, Length=111, Percent_Identity=40.5405405405405, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323274, Length=132, Percent_Identity=31.8181818181818, Blast_Score=78, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19920920, Length=156, Percent_Identity=41.025641025641, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24582744, Length=102, Percent_Identity=46.078431372549, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582741, Length=159, Percent_Identity=32.7044025157233, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 17054; Mature: 16923

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGPRPHALAQDRQPRPPARTEIIMPASDTDTIHPLRAAAATVRQNAHAPYSNFKVGAA
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECEE
IRAKSGTVYVGCNVENVAYPEGTCAEAGAIAAMVAAGETELLEAYVIADCPSPVPPCGGC
EEECCCEEEEECCCCCEECCCCCCCHHHHHEEHHHCCCHHHEEEEEEECCCCCCCCCCHH
RQKLKEFGAAEVAVTLATTDGVEMQTTIGDLLPGAFDAGHMERS
HHHHHHCCCCEEEEEEEECCCCEEHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PQGPRPHALAQDRQPRPPARTEIIMPASDTDTIHPLRAAAATVRQNAHAPYSNFKVGAA
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECEE
IRAKSGTVYVGCNVENVAYPEGTCAEAGAIAAMVAAGETELLEAYVIADCPSPVPPCGGC
EEECCCEEEEECCCCCEECCCCCCCHHHHHEEHHHCCCHHHEEEEEEECCCCCCCCCCHH
RQKLKEFGAAEVAVTLATTDGVEMQTTIGDLLPGAFDAGHMERS
HHHHHHCCCCEEEEEEEECCCCEEHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]