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The map label for this gene is walR [H]

Identifier: 99081350

GI number: 99081350

Start: 1615337

End: 1615750

Strand: Reverse

Name: walR [H]

Synonym: TM1040_1509

Alternate gene names: 99081350

Gene position: 1615750-1615337 (Counterclockwise)

Preceding gene: 99081351

Following gene: 99081349

Centisome position: 50.48

GC content: 59.18

Gene sequence:

>414_bases
ATGGCTGGACGAGTCGTTTTGATTGAAGACGAAGCCAATATCGCCGAGGCGATCCGCTTCTTGTTGTCGCGCGAGGGGTG
GCAGGTCGATGTTCATGCCGATGGCGGCACTGCGGTTTCCGTGATCGAAGCCAAAAAACCCGATCTGGTGATTTTGGATC
TGATGCTGCCGGGCAAGAGTGGCATGGAAATTATCCGTGAACTCAGGGAGTTGAGCGCGTTTTCGGATCTGCCTGTGCTA
ATGTTGACCGCACGCGGGCAACTCAAGGACCGCGAAATGGCAGAGCGCGCCGGTGTGACCCGTTTTATGACCAAGCCGTT
CTCCAACACCGAAGTGTTGACGGCCGTGCGCGATCTTGATGCGCAGGCGCGGCAGTCTCAGGCGCAGGCAGCGGCCGTGC
GCGACGCCGGCTGA

Upstream 100 bases:

>100_bases
AACTGCTGGGTGACAGCCGCGCTGCTTTCATGCAAAGATTGCTACCGCACCCGGAGGAACCGGTAACACGGTGTGGTGCT
TGGGGAGGACAAGGACATCA

Downstream 100 bases:

>100_bases
GCCGCGCGGGATGATCCGATCTGATGGCGCAGGCAGCAAGGACGAGCTGCGCGCTCCTTTTGTGGAGCGCCGGACGTATC
GCCGTCGTCGCCTGATGGAT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MAGRVVLIEDEANIAEAIRFLLSREGWQVDVHADGGTAVSVIEAKKPDLVILDLMLPGKSGMEIIRELRELSAFSDLPVL
MLTARGQLKDREMAERAGVTRFMTKPFSNTEVLTAVRDLDAQARQSQAQAAAVRDAG

Sequences:

>Translated_137_residues
MAGRVVLIEDEANIAEAIRFLLSREGWQVDVHADGGTAVSVIEAKKPDLVILDLMLPGKSGMEIIRELRELSAFSDLPVL
MLTARGQLKDREMAERAGVTRFMTKPFSNTEVLTAVRDLDAQARQSQAQAAAVRDAG
>Mature_136_residues
AGRVVLIEDEANIAEAIRFLLSREGWQVDVHADGGTAVSVIEAKKPDLVILDLMLPGKSGMEIIRELRELSAFSDLPVLM
LTARGQLKDREMAERAGVTRFMTKPFSNTEVLTAVRDLDAQARQSQAQAAAVRDAG

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=41.025641025641, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI1790860, Length=130, Percent_Identity=36.1538461538462, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1789402, Length=128, Percent_Identity=39.84375, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788394, Length=140, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-15,
Organism=Escherichia coli, GI87082012, Length=134, Percent_Identity=34.3283582089552, Blast_Score=73, Evalue=8e-15,
Organism=Escherichia coli, GI1786784, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1787375, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=114, Percent_Identity=29.8245614035088, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=142, Percent_Identity=29.5774647887324, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1786911, Length=113, Percent_Identity=36.283185840708, Blast_Score=63, Evalue=8e-12,
Organism=Escherichia coli, GI145693140, Length=101, Percent_Identity=35.6435643564356, Blast_Score=61, Evalue=3e-11,
Organism=Escherichia coli, GI1790863, Length=116, Percent_Identity=29.3103448275862, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14948; Mature: 14817

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRVVLIEDEANIAEAIRFLLSREGWQVDVHADGGTAVSVIEAKKPDLVILDLMLPGKS
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCEEEEEEECCCCC
GMEIIRELRELSAFSDLPVLMLTARGQLKDREMAERAGVTRFMTKPFSNTEVLTAVRDLD
CHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCHHHHCCCCCCCHHHHHHHHCC
AQARQSQAQAAAVRDAG
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGRVVLIEDEANIAEAIRFLLSREGWQVDVHADGGTAVSVIEAKKPDLVILDLMLPGKS
CCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCEEEEEEECCCCC
GMEIIRELRELSAFSDLPVLMLTARGQLKDREMAERAGVTRFMTKPFSNTEVLTAVRDLD
CHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCHHHHCCCCCCCHHHHHHHHCC
AQARQSQAQAAAVRDAG
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA