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The map label for this gene is xerD [H]

Identifier: 99081269

GI number: 99081269

Start: 1525837

End: 1526790

Strand: Reverse

Name: xerD [H]

Synonym: TM1040_1428

Alternate gene names: 99081269

Gene position: 1526790-1525837 (Counterclockwise)

Preceding gene: 99081270

Following gene: 99081268

Centisome position: 47.7

GC content: 60.8

Gene sequence:

>954_bases
ATGCTGGCACCCGCGGACGATCTGCAATGGATTTCGACCTTTCTCGATGCGCAGGCCGCAGAACTCGGTGCAGCGCGCAA
CACGCTGCTGGCTTACGGGCGGGACCTTCGGAATGTCACCACCTGGATGCGCACCAAAGGGCAGAGCTTTGCGCAGATGC
AACAGGCTGACATCGAGGCCTATCTGATCTCATGCGATGCCGAGGGGCTGAGCCGCGCCACGCGTGCACGCCGCTTGTCC
GCGATCAAGCAGATTTACCGTTTTGCTTTTGAAGAAGGATGGCGGCAGGACAACCCTGCCTTGCAGATCAAAGGACCGGG
GCGCGACAAATCACTGCCCAAGACCCTTGATGAGGCAGAAGTTGATCGCCTCCTTGCTGCCGCGCGCGAAGTCGGGCGAA
CCGAGGCCGACAGGTTGCGCAACACCTGCCTGATGGAGCTTTTGTACGCGACGGGCATGCGGGTGAGCGAGCTGGTCTCG
TTGCCGGTGTCCGCCACCCGAGGTGATCCCAACATGCTGTTGATCCTCGGCAAAGGTGGAAAAGAACGTATGGTCCCACT
GTCGCCACCCGCCCGCGCGGCGCTGGGGGCGTGGATCGTGCTGCGCGACAGTCTTGAGGACAAGCGCGAAGGGCAGGGGC
ACAAGGCATCGCGCTTTCTCTTTCCCTCGCGCAGTAAAGAGGGCCATCTTACGCGGCACCGGTTTTATCTCCTGATCAAA
GAACTGGCGGTCGCAGGCGGCGTCTCGCCCGAAAAGGTCACACCGCATACTCTGCGTCATGCCTTTGCCACGCATCTGTT
GCAAAACGGTGCAGACCTCAGGGCGATTCAGGCGCTCTTGGGGCATGCGGATATTGCGACAACCGAGATCTACACCCATG
TGCTGGATGCGCGGCTGGCGGAGTTGGTACACCAGCATCACCCGCTTGCGGCAAAAGACGACGAAACTCGTTGA

Upstream 100 bases:

>100_bases
AATCACCTTGTCACTCGCGGCGTTTCGGCGGATGGGTCTTGAAGACAGCGCCCGCCGCGCAGCGCTGCAGCTCCTGTTGT
TGCCGCGAGGAAGCTGAACC

Downstream 100 bases:

>100_bases
TTTCGGGGGGCGCGCCGCTTGAACCACGGCGCTCTGCACCCCATAACCACTGAAACCCCACATCAATCAGGACCCTAAAA
TGGACAGCGCTACAGCCGCA

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MLAPADDLQWISTFLDAQAAELGAARNTLLAYGRDLRNVTTWMRTKGQSFAQMQQADIEAYLISCDAEGLSRATRARRLS
AIKQIYRFAFEEGWRQDNPALQIKGPGRDKSLPKTLDEAEVDRLLAAAREVGRTEADRLRNTCLMELLYATGMRVSELVS
LPVSATRGDPNMLLILGKGGKERMVPLSPPARAALGAWIVLRDSLEDKREGQGHKASRFLFPSRSKEGHLTRHRFYLLIK
ELAVAGGVSPEKVTPHTLRHAFATHLLQNGADLRAIQALLGHADIATTEIYTHVLDARLAELVHQHHPLAAKDDETR

Sequences:

>Translated_317_residues
MLAPADDLQWISTFLDAQAAELGAARNTLLAYGRDLRNVTTWMRTKGQSFAQMQQADIEAYLISCDAEGLSRATRARRLS
AIKQIYRFAFEEGWRQDNPALQIKGPGRDKSLPKTLDEAEVDRLLAAAREVGRTEADRLRNTCLMELLYATGMRVSELVS
LPVSATRGDPNMLLILGKGGKERMVPLSPPARAALGAWIVLRDSLEDKREGQGHKASRFLFPSRSKEGHLTRHRFYLLIK
ELAVAGGVSPEKVTPHTLRHAFATHLLQNGADLRAIQALLGHADIATTEIYTHVLDARLAELVHQHHPLAAKDDETR
>Mature_317_residues
MLAPADDLQWISTFLDAQAAELGAARNTLLAYGRDLRNVTTWMRTKGQSFAQMQQADIEAYLISCDAEGLSRATRARRLS
AIKQIYRFAFEEGWRQDNPALQIKGPGRDKSLPKTLDEAEVDRLLAAAREVGRTEADRLRNTCLMELLYATGMRVSELVS
LPVSATRGDPNMLLILGKGGKERMVPLSPPARAALGAWIVLRDSLEDKREGQGHKASRFLFPSRSKEGHLTRHRFYLLIK
ELAVAGGVSPEKVTPHTLRHAFATHLLQNGADLRAIQALLGHADIATTEIYTHVLDARLAELVHQHHPLAAKDDETR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=305, Percent_Identity=42.6229508196721, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=31.4878892733564, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1790767, Length=185, Percent_Identity=32.972972972973, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790768, Length=176, Percent_Identity=31.25, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35210; Mature: 35210

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPADDLQWISTFLDAQAAELGAARNTLLAYGRDLRNVTTWMRTKGQSFAQMQQADIEA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEE
YLISCDAEGLSRATRARRLSAIKQIYRFAFEEGWRQDNPALQIKGPGRDKSLPKTLDEAE
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHH
VDRLLAAAREVGRTEADRLRNTCLMELLYATGMRVSELVSLPVSATRGDPNMLLILGKGG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEEECCC
KERMVPLSPPARAALGAWIVLRDSLEDKREGQGHKASRFLFPSRSKEGHLTRHRFYLLIK
CCCCCCCCCCHHHHHHHHHEECCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ELAVAGGVSPEKVTPHTLRHAFATHLLQNGADLRAIQALLGHADIATTEIYTHVLDARLA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELVHQHHPLAAKDDETR
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLAPADDLQWISTFLDAQAAELGAARNTLLAYGRDLRNVTTWMRTKGQSFAQMQQADIEA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEE
YLISCDAEGLSRATRARRLSAIKQIYRFAFEEGWRQDNPALQIKGPGRDKSLPKTLDEAE
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHH
VDRLLAAAREVGRTEADRLRNTCLMELLYATGMRVSELVSLPVSATRGDPNMLLILGKGG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEEECCC
KERMVPLSPPARAALGAWIVLRDSLEDKREGQGHKASRFLFPSRSKEGHLTRHRFYLLIK
CCCCCCCCCCHHHHHHHHHEECCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ELAVAGGVSPEKVTPHTLRHAFATHLLQNGADLRAIQALLGHADIATTEIYTHVLDARLA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELVHQHHPLAAKDDETR
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]