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The map label for this gene is hflX [H]

Identifier: 99081196

GI number: 99081196

Start: 1446786

End: 1448057

Strand: Reverse

Name: hflX [H]

Synonym: TM1040_1355

Alternate gene names: 99081196

Gene position: 1448057-1446786 (Counterclockwise)

Preceding gene: 99081197

Following gene: 99081194

Centisome position: 45.24

GC content: 59.51

Gene sequence:

>1272_bases
ATGGAGCATGACAGGAAGCAGACCCGGGCTTGGGTTCTGCATCCGGATATCAAGTCAGATAGGGATCGTCGCGACGCAGT
TCCGGCGCTAGAGGAAGGTGTGGCGCTCGCCGCCGCACTGCCCGACCTTGAAGTGGTCGGCTCAACTGTCGTGGGCCTTC
CCAAGGCGCATCCCGGTATGCTGTTTGGCTCCGGCAAGATCGAAGAGCTGAAGACCCTGTTCAAAGCCGAAGAGGTCGAA
CTGGTCTTGATTGACGGCCCCGTAAGCCCGGTCCAGCAGCGCAACCTCGAAAAAGCCTGGAAGGTCAAAATTCTTGACCG
AACCGGGCTTATTCTCGAGATCTTCTCGGATCGTGCGCGCACCCGTGAGGGCGTGCTGCAGGTTGAAATGGCAGCGCTCA
GCTATCAGCGCACGCGACTGGTGCGTGCCTGGACCCACCTAGAGCGTCAGCGTGGTGGTCTTGGCTTTGTCGGCGGCCCC
GGCGAAACCCAGATCGAAGCGGACCGCCGCGCCATCGACGAACAGCTTGTCCGACTGCGGCGACAACTCGACAAGGTTGT
GAAAACGCGTACGCTGCATCGCGCCGCGCGCGCCAAAGTGCCTTATCCGATTGTTGCGCTTGTGGGATATACCAACGCTG
GAAAATCCACTCTGTTCAATCGTCTGACCGGGGCAGAGGTGATGGCGAAAGACATGCTCTTTGCCACGCTGGACCCCACC
ATGCGCCGCGTTGAGCTGCCGGATGGGCCAGAAGTCATCCTCTCGGACACCGTGGGATTCATCTCTGATCTTCCGACCGA
ACTGGTTGCCTCGTTTCGCGCGACGCTCGAAGAGGTGCTGGCCGCAGATGTGATCCTACATGTGCGCGACATCAGCCACA
GCGACACCGAACATCAGGCCGAAGACGTGGAGCAGATCCTGAGCTCGCTTGGAGTGGACGAGGACCGCACGGTCATCGAG
GTCTGGAACAAGATCGACCAGCTCTCCGAGGAAGAGGCGGATGCCTGCCGCCAACGGGCAGACCGCAACGACTCGCTCTA
CGCGATTTCCGCGATAACCGGCGAGGGGCTGCCTCAACTGTTGCACGACATTGCCATGAAGCTTCAGGGCGTGCGTGTGG
ATGAGGTACTGACGCTGGACTTTTCCCAAGGAAAACAGCGCGCCTGGCTCTTCAAACAAGACGTTGTGCAAGAGGAAAAC
CAGACCGACACCGGGTTTGAGATTTCCGTGCGCTGGACCGAAAAGCAAAAAGCACAATACGCAGCGCTCTAG

Upstream 100 bases:

>100_bases
TGCGCCGCGATGGCCAGTCGCAGCTTGTCTACAAGCATGCGATTTCCACCATCATGCCGGCCCAGCCCATCAGCCTATAT
GAAGGTGAAGACTCCAATTG

Downstream 100 bases:

>100_bases
AGCGCTGCGTTTTTCTTTAGTTGCGCGGCAGGATACGGGTGACGCCGACGGAAGCGGCGCGCGCCAGTTTTTCGTCGAGA
GACATCGGGATATACTCCCC

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MEHDRKQTRAWVLHPDIKSDRDRRDAVPALEEGVALAAALPDLEVVGSTVVGLPKAHPGMLFGSGKIEELKTLFKAEEVE
LVLIDGPVSPVQQRNLEKAWKVKILDRTGLILEIFSDRARTREGVLQVEMAALSYQRTRLVRAWTHLERQRGGLGFVGGP
GETQIEADRRAIDEQLVRLRRQLDKVVKTRTLHRAARAKVPYPIVALVGYTNAGKSTLFNRLTGAEVMAKDMLFATLDPT
MRRVELPDGPEVILSDTVGFISDLPTELVASFRATLEEVLAADVILHVRDISHSDTEHQAEDVEQILSSLGVDEDRTVIE
VWNKIDQLSEEEADACRQRADRNDSLYAISAITGEGLPQLLHDIAMKLQGVRVDEVLTLDFSQGKQRAWLFKQDVVQEEN
QTDTGFEISVRWTEKQKAQYAAL

Sequences:

>Translated_423_residues
MEHDRKQTRAWVLHPDIKSDRDRRDAVPALEEGVALAAALPDLEVVGSTVVGLPKAHPGMLFGSGKIEELKTLFKAEEVE
LVLIDGPVSPVQQRNLEKAWKVKILDRTGLILEIFSDRARTREGVLQVEMAALSYQRTRLVRAWTHLERQRGGLGFVGGP
GETQIEADRRAIDEQLVRLRRQLDKVVKTRTLHRAARAKVPYPIVALVGYTNAGKSTLFNRLTGAEVMAKDMLFATLDPT
MRRVELPDGPEVILSDTVGFISDLPTELVASFRATLEEVLAADVILHVRDISHSDTEHQAEDVEQILSSLGVDEDRTVIE
VWNKIDQLSEEEADACRQRADRNDSLYAISAITGEGLPQLLHDIAMKLQGVRVDEVLTLDFSQGKQRAWLFKQDVVQEEN
QTDTGFEISVRWTEKQKAQYAAL
>Mature_423_residues
MEHDRKQTRAWVLHPDIKSDRDRRDAVPALEEGVALAAALPDLEVVGSTVVGLPKAHPGMLFGSGKIEELKTLFKAEEVE
LVLIDGPVSPVQQRNLEKAWKVKILDRTGLILEIFSDRARTREGVLQVEMAALSYQRTRLVRAWTHLERQRGGLGFVGGP
GETQIEADRRAIDEQLVRLRRQLDKVVKTRTLHRAARAKVPYPIVALVGYTNAGKSTLFNRLTGAEVMAKDMLFATLDPT
MRRVELPDGPEVILSDTVGFISDLPTELVASFRATLEEVLAADVILHVRDISHSDTEHQAEDVEQILSSLGVDEDRTVIE
VWNKIDQLSEEEADACRQRADRNDSLYAISAITGEGLPQLLHDIAMKLQGVRVDEVLTLDFSQGKQRAWLFKQDVVQEEN
QTDTGFEISVRWTEKQKAQYAAL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=277, Percent_Identity=35.0180505415162, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI310133116, Length=263, Percent_Identity=35.7414448669202, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI310124269, Length=244, Percent_Identity=36.4754098360656, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI310124267, Length=244, Percent_Identity=36.4754098360656, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI310124171, Length=244, Percent_Identity=36.4754098360656, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI310124169, Length=244, Percent_Identity=36.4754098360656, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1790615, Length=398, Percent_Identity=42.4623115577889, Blast_Score=288, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI17561038, Length=416, Percent_Identity=31.9711538461538, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24650079, Length=410, Percent_Identity=35.8536585365854, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47375; Mature: 47375

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHDRKQTRAWVLHPDIKSDRDRRDAVPALEEGVALAAALPDLEVVGSTVVGLPKAHPGM
CCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHCCCHHHHCCCHHHHCCHHHCCCCCCCCE
LFGSGKIEELKTLFKAEEVELVLIDGPVSPVQQRNLEKAWKVKILDRTGLILEIFSDRAR
EECCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHCCCHHHEEEEECCCCHHHHHHHHHHH
TREGVLQVEMAALSYQRTRLVRAWTHLERQRGGLGFVGGPGETQIEADRRAIDEQLVRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
RQLDKVVKTRTLHRAARAKVPYPIVALVGYTNAGKSTLFNRLTGAEVMAKDMLFATLDPT
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCCH
MRRVELPDGPEVILSDTVGFISDLPTELVASFRATLEEVLAADVILHVRDISHSDTEHQA
HHEEECCCCCCEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EDVEQILSSLGVDEDRTVIEVWNKIDQLSEEEADACRQRADRNDSLYAISAITGEGLPQL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHH
LHDIAMKLQGVRVDEVLTLDFSQGKQRAWLFKQDVVQEENQTDTGFEISVRWTEKQKAQY
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHH
AAL
CCC
>Mature Secondary Structure
MEHDRKQTRAWVLHPDIKSDRDRRDAVPALEEGVALAAALPDLEVVGSTVVGLPKAHPGM
CCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHCCCHHHHCCCHHHHCCHHHCCCCCCCCE
LFGSGKIEELKTLFKAEEVELVLIDGPVSPVQQRNLEKAWKVKILDRTGLILEIFSDRAR
EECCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHCCCHHHEEEEECCCCHHHHHHHHHHH
TREGVLQVEMAALSYQRTRLVRAWTHLERQRGGLGFVGGPGETQIEADRRAIDEQLVRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
RQLDKVVKTRTLHRAARAKVPYPIVALVGYTNAGKSTLFNRLTGAEVMAKDMLFATLDPT
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCCH
MRRVELPDGPEVILSDTVGFISDLPTELVASFRATLEEVLAADVILHVRDISHSDTEHQA
HHEEECCCCCCEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EDVEQILSSLGVDEDRTVIEVWNKIDQLSEEEADACRQRADRNDSLYAISAITGEGLPQL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHH
LHDIAMKLQGVRVDEVLTLDFSQGKQRAWLFKQDVVQEENQTDTGFEISVRWTEKQKAQY
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHH
AAL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]