BacMap

Definition	Ruegeria sp. TM1040, complete genome.
Accession	NC_008044
Length	3,200,938

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The map label for this gene is bdhA [H]

Identifier: 99081183

GI number: 99081183

Start: 1429486

End: 1430259

Strand: Reverse

Name: bdhA [H]

Synonym: TM1040_1342

Alternate gene names: 99081183

Gene position: 1430259-1429486 (Counterclockwise)

Preceding gene: 99081186

Following gene: 99081182

Centisome position: 44.68

GC content: 58.91

Gene sequence:

>774_bases
ATGTCCGTCAAAGGTAAAACCGCAGTGATCACCGGGTCCAATTCCGGAATCGGTCTGGGTGTCGCCCGGGAATTGGCCAA
GGCTGGCGCCAATGTTGTGTTGAACTCTTTCACCGATCGCGATGAAGACCACGCCATCGCCGCCGAGATCGGCAAGGAAT
TTGGAGTGGAGGCGCGTTATATTCAGGCGGATATGTCCAAAGCGGAGCAATGCCGCGCGCTGATCGAGACGGCGGGCCAA
TGCGATATTCTTGTGAACAATGCCGGCATCCAGCATGTTGCCCCGATTGACAGCTTCCCCACCGAAAAATGGGACGCGAT
CATTGCGATCAACCTCACCTCTGCGTTTCACACCACGGCGGCGGCCCTGCCGATGATGCGCGCGGCCGGTTGGGGCAGGG
TGGTAAACATCGCCTCGGCCCATGGGCTGACGGCCTCTCCCTATAAATCGGCCTATGTCGCGGCCAAACACGGGATTGTG
GGCATGACAAAAACCGTTGCGCTTGAGACCGCCGAAGAGCCTATCACCTGCAACGCGGTCTGTCCGGGTTATGTGCTGAC
CCCATTGGTGGAGGCGCAAATCCCTGACACCATGGAGAAATACAACATGGGGCGCGAAGAGGTCATCAAGAAGGTGATGC
TCGAACGCCAGCCCTCGCGAGAGTTTGCCACCGTCGAACAACTGGGCGGGACCGTGAATTTCCTCTGCTCGGATGCGGCC
AAGCAAATCACCGGAACCACCATCAGCGTCGACGGCGGCTGGACCGCACTCTGA

Upstream 100 bases:

>100_bases
GCACTCCTGTGATGTAAATTTCCGATCCGAAGGGCGTTTATTTTGCGCCTGCAGCATGCGAAGCTGAGCGAAAGGAAAGC
AGGCTAGCAGAGGAATGCTC

Downstream 100 bases:

>100_bases
GGATGCCTGCGCGCGGCCGGGGCACTGAACCGGCAGCGCGCATCTGTGCCGGGACCTGAATGTTCAGGACCGGAACGCGA
GGGAAACAGCAACCATGGTC

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSVKGKTAVITGSNSGIGLGVARELAKAGANVVLNSFTDRDEDHAIAAEIGKEFGVEARYIQADMSKAEQCRALIETAGQ
CDILVNNAGIQHVAPIDSFPTEKWDAIIAINLTSAFHTTAAALPMMRAAGWGRVVNIASAHGLTASPYKSAYVAAKHGIV
GMTKTVALETAEEPITCNAVCPGYVLTPLVEAQIPDTMEKYNMGREEVIKKVMLERQPSREFATVEQLGGTVNFLCSDAA
KQITGTTISVDGGWTAL

Sequences:

>Translated_257_residues
MSVKGKTAVITGSNSGIGLGVARELAKAGANVVLNSFTDRDEDHAIAAEIGKEFGVEARYIQADMSKAEQCRALIETAGQ
CDILVNNAGIQHVAPIDSFPTEKWDAIIAINLTSAFHTTAAALPMMRAAGWGRVVNIASAHGLTASPYKSAYVAAKHGIV
GMTKTVALETAEEPITCNAVCPGYVLTPLVEAQIPDTMEKYNMGREEVIKKVMLERQPSREFATVEQLGGTVNFLCSDAA
KQITGTTISVDGGWTAL
>Mature_256_residues
SVKGKTAVITGSNSGIGLGVARELAKAGANVVLNSFTDRDEDHAIAAEIGKEFGVEARYIQADMSKAEQCRALIETAGQC
DILVNNAGIQHVAPIDSFPTEKWDAIIAINLTSAFHTTAAALPMMRAAGWGRVVNIASAHGLTASPYKSAYVAAKHGIVG
MTKTVALETAEEPITCNAVCPGYVLTPLVEAQIPDTMEKYNMGREEVIKKVMLERQPSREFATVEQLGGTVNFLCSDAAK
QITGTTISVDGGWTAL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=33.9920948616601, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=29.9212598425197, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=31.2267657992565, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=31.9066147859922, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=28.4090909090909, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=29.5719844357977, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI31542939, Length=218, Percent_Identity=31.651376146789, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=28.4210526315789, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI33667109, Length=258, Percent_Identity=29.8449612403101, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=29.5719844357977, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705855, Length=203, Percent_Identity=33.0049261083744, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI142976729, Length=220, Percent_Identity=30.9090909090909, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4503301, Length=257, Percent_Identity=29.1828793774319, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=32.2222222222222, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=31.4285714285714, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=28.0632411067194, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=240, Percent_Identity=30.4166666666667, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4557649, Length=183, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI209862901, Length=237, Percent_Identity=27.8481012658228, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI19923983, Length=237, Percent_Identity=27.8481012658228, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=30.5699481865285, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=26.5625, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=28.3582089552239, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI225579078, Length=211, Percent_Identity=30.3317535545024, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI40807363, Length=239, Percent_Identity=26.3598326359833, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=216, Percent_Identity=27.3148148148148, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI150247226, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=33.0769230769231, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=36.2934362934363, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=32.183908045977, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=33.0708661417323, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=31.5175097276265, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=30.6201550387597, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=28.4046692607004, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.7937743190661, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=29.5019157088123, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789378, Length=214, Percent_Identity=28.5046728971963, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=27.734375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=25.9842519685039, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786701, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=30.4182509505703, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=29.6875, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=29.5719844357977, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=28.2442748091603, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=212, Percent_Identity=31.1320754716981, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=29.7297297297297, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=32.3076923076923, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=31.9796954314721, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=32.6424870466321, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=266, Percent_Identity=28.1954887218045, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=29.9625468164794, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17555612, Length=218, Percent_Identity=31.1926605504587, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=27.9850746268657, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=279, Percent_Identity=29.7491039426523, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=26.5454545454545, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560176, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=29.7794117647059, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=25.8555133079848, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI86565303, Length=217, Percent_Identity=29.9539170506912, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997402, Length=190, Percent_Identity=30.5263157894737, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=27.9850746268657, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=280, Percent_Identity=27.8571428571429, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=29.4545454545455, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=30.2919708029197, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=222, Percent_Identity=28.8288288288288, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=221, Percent_Identity=28.9592760180996, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319635, Length=198, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=30.7392996108949, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=31.4176245210728, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571526, Length=265, Percent_Identity=31.3207547169811, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21357041, Length=262, Percent_Identity=30.1526717557252, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=30.8880308880309, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=35.9375, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=35.9375, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI18859837, Length=263, Percent_Identity=26.9961977186312, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=33.6842105263158, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=33.6842105263158, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=29.2307692307692, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=25.0996015936255, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=28.4974093264249, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221331218, Length=207, Percent_Identity=30.9178743961353, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24665243, Length=207, Percent_Identity=30.9178743961353, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737361, Length=215, Percent_Identity=26.9767441860465, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331216, Length=208, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24665247, Length=208, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=28.3236994219653, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584752, Length=190, Percent_Identity=30.5263157894737, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27183; Mature: 27052

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKGKTAVITGSNSGIGLGVARELAKAGANVVLNSFTDRDEDHAIAAEIGKEFGVEARY
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEE
IQADMSKAEQCRALIETAGQCDILVNNAGIQHVAPIDSFPTEKWDAIIAINLTSAFHTTA
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEEEECHHHHHHH
AALPMMRAAGWGRVVNIASAHGLTASPYKSAYVAAKHGIVGMTKTVALETAEEPITCNAV
HHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHEEEEECCCCCEEECCC
CPGYVLTPLVEAQIPDTMEKYNMGREEVIKKVMLERQPSREFATVEQLGGTVNFLCSDAA
CCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEHHHHHH
KQITGTTISVDGGWTAL
HHHCCCEEEECCCCCCC
>Mature Secondary Structure 
SVKGKTAVITGSNSGIGLGVARELAKAGANVVLNSFTDRDEDHAIAAEIGKEFGVEARY
CCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEE
IQADMSKAEQCRALIETAGQCDILVNNAGIQHVAPIDSFPTEKWDAIIAINLTSAFHTTA
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEEEECHHHHHHH
AALPMMRAAGWGRVVNIASAHGLTASPYKSAYVAAKHGIVGMTKTVALETAEEPITCNAV
HHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCHHEEEEECCCCCEEECCC
CPGYVLTPLVEAQIPDTMEKYNMGREEVIKKVMLERQPSREFATVEQLGGTVNFLCSDAA
CCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHEEHHHHHH
KQITGTTISVDGGWTAL
HHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]