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The map label for this gene is gpt [H]

Identifier: 99080987

GI number: 99080987

Start: 1234272

End: 1234802

Strand: Reverse

Name: gpt [H]

Synonym: TM1040_1146

Alternate gene names: 99080987

Gene position: 1234802-1234272 (Counterclockwise)

Preceding gene: 99080988

Following gene: 99080986

Centisome position: 38.58

GC content: 63.09

Gene sequence:

>531_bases
ATGAGCACCAAGGATCCGAACCGCCTGCCCCACGAGAAGGGGTTTCACATCTCCTGGGATCAAATCCACCGAGACAGCCG
CGCGCTGGCGTGGCGTCTGGACGGGCTTGGCCCCGACGATGGCCATTGGCGCGCCGTGGTGGCGATCACCCGCGGGGGCA
TGGCGCCCGCAATGATCGTCGCGCGCGAGCTGGATATCCGCACGGTGGATACCATCAGCGTGAAATCCTACCACTCCGGC
GGCGGCAAGGCTGATCAGCGTCGCGAGGCCGAGGTGCTCAAGAGCCCCGACGCGGACATCATGGGCGATGGGACCGGCAT
CCTGATCGTGGATGATCTGGTCGACTCCGGCAAAACGCTGGAACTGGTGCGCACCCTCTATCCCAAGGCGCATTTTGCCA
CCGTCTACGCCAAGCCCCAGGGTGAGCCGCAGGTCGATACCTTTATCACGGGCGTGAGCCAGGACACCTGGATCTTTTTC
CCGTGGGATATGGCGTTGCAGTATGTCGAACCTTACCGGGGTACGGATTGA

Upstream 100 bases:

>100_bases
CTCCGGTGTGACCGGCGAGAACCTGCATGTGGATGCGGGTTATCATGTGGTCGGCATGAAGGCCGTGGACGCCCCCGATA
TCGAGAAAGGCTAACCCCTG

Downstream 100 bases:

>100_bases
CCCAGCGTCAATTTAGAAAATGACAAAACGCGCCCCTGTTGGCGCGTTTTCTTTTTTGGCTTTGTTTTCCATCTCTTGTC
TTGAGATTTGAAAAGCGGCC

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSTKDPNRLPHEKGFHISWDQIHRDSRALAWRLDGLGPDDGHWRAVVAITRGGMAPAMIVARELDIRTVDTISVKSYHSG
GGKADQRREAEVLKSPDADIMGDGTGILIVDDLVDSGKTLELVRTLYPKAHFATVYAKPQGEPQVDTFITGVSQDTWIFF
PWDMALQYVEPYRGTD

Sequences:

>Translated_176_residues
MSTKDPNRLPHEKGFHISWDQIHRDSRALAWRLDGLGPDDGHWRAVVAITRGGMAPAMIVARELDIRTVDTISVKSYHSG
GGKADQRREAEVLKSPDADIMGDGTGILIVDDLVDSGKTLELVRTLYPKAHFATVYAKPQGEPQVDTFITGVSQDTWIFF
PWDMALQYVEPYRGTD
>Mature_175_residues
STKDPNRLPHEKGFHISWDQIHRDSRALAWRLDGLGPDDGHWRAVVAITRGGMAPAMIVARELDIRTVDTISVKSYHSGG
GKADQRREAEVLKSPDADIMGDGTGILIVDDLVDSGKTLELVRTLYPKAHFATVYAKPQGEPQVDTFITGVSQDTWIFFP
WDMALQYVEPYRGTD

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=160, Percent_Identity=43.125, Blast_Score=138, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 19620; Mature: 19489

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKDPNRLPHEKGFHISWDQIHRDSRALAWRLDGLGPDDGHWRAVVAITRGGMAPAMIV
CCCCCCCCCCCCCCCEEEHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEE
ARELDIRTVDTISVKSYHSGGGKADQRREAEVLKSPDADIMGDGTGILIVDDLVDSGKTL
EEECCCEEEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCHH
ELVRTLYPKAHFATVYAKPQGEPQVDTFITGVSQDTWIFFPWDMALQYVEPYRGTD
HHHHHHCCCCEEEEEEECCCCCCCHHHEEECCCCCCEEEEEHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STKDPNRLPHEKGFHISWDQIHRDSRALAWRLDGLGPDDGHWRAVVAITRGGMAPAMIV
CCCCCCCCCCCCCCEEEHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEE
ARELDIRTVDTISVKSYHSGGGKADQRREAEVLKSPDADIMGDGTGILIVDDLVDSGKTL
EEECCCEEEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCHH
ELVRTLYPKAHFATVYAKPQGEPQVDTFITGVSQDTWIFFPWDMALQYVEPYRGTD
HHHHHHCCCCEEEEEEECCCCCCCHHHEEECCCCCCEEEEEHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA