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The map label for this gene is argE [H]

Identifier: 99080558

GI number: 99080558

Start: 773813

End: 774979

Strand: Direct

Name: argE [H]

Synonym: TM1040_0717

Alternate gene names: 99080558

Gene position: 773813-774979 (Clockwise)

Preceding gene: 99080557

Following gene: 99080559

Centisome position: 24.17

GC content: 61.01

Gene sequence:

>1167_bases
ATGATCCAACGGCTTTCACCGCTGGAGATCATGATACGTCTGGTCTCCTTTCCGACCGTGAGCAGCGAAACCAATCTGCC
GCTCATTGAGTGGACGTCGGAGTATCTGAGCGCGCATGGGATCGAGCATCATGTCTGGATCGATCCCGAACAGCCCGAAA
AAGCCGGGCTCTATGCTCATGTTGGCCCGAAGGTCGAAGGCGGAGTCGTGCTGTCGGGGCACACCGATGTTGTGCCCGTC
GAGGGACAGGACTGGAGCTCTGACCCATTTGAGGTGGTGGAGCGGGACGGCAAGTATTTTGGCCGTGGCTGCGCGGATAT
GAAGGGGTTTGACGCGCTGGCGCTCTGGGCGCTGGTCGAGGGGAACTACACCGATCTGCAGCGCCCGCTTCAGTTGGCCT
TCACCTTTGACGAGGAAATTGGCTGCACCGGCGCGCCGCCCCTGATCGAGGAAATGCAGAAATATCTGCCCAAGGCCGAG
GCGGTCATCGTGGGCGAGCCGTCGATGCTCAAGGCGGTGACGGGTCACAAGGGCGCCTTTGCGATGGCGACTCATGTGCG
CGGCTTTGAGGTTCACAGCTCGCTGATGCATGAAGGTGTGAGCGCCGTGATGGAGGCGGCGCGCATTGTCGACTGGGCCA
ACCATCGCAACGCCGAAAACCGCGCAAGGCCCCAGACCGAGGTCGCGGCCATGTTCACGCCGCCCTGGACCACGGTGCAT
GTGGGCAAAATATCGGGTGGGACCGCGCATAACATCACGGCAGGGGACTGTAATTTCTGGATGGATTTCCGGGTCGTCCC
GGGTGAGAGCCTTGCCGATTGGCAGGCGGCATATGAGGCGGAAATCGCCCGCATCGAGGCCGAGATGCAGAGGGTGCGCC
CAGAAGCAGGGATCACGCTTGAAAAAGTCTTTAGCGTGCCGGGGCTCGCGCCGGAGACCGATGGTGCCGCAGAAACATTG
GTGCGTGCGCTCACCGGTGACAACGCCCGCCATGTGGTGAGCTATGGCACCGAGGCCGGTCACTATCAGGTTGCGGGCTA
CTCCGCAGTGGTCTGCGGCCCCGGTGACATCGCACAAGCGCATCAGGCGGATGAGTTTATCACCGTTGCGCAATTTGAGG
CCGGTACAAAGTTCATGCAAGATCTGCTTTCGCGTCTCTCTGCATAG

Upstream 100 bases:

>100_bases
ATCGCCGATCCACGACATGAACTATCAGGCAGAGCCCTCGCAATACATGGAAGTGGAGCCGGGGCACTTTGTGCTGACCA
CCGATTCTGGCTATTGATCC

Downstream 100 bases:

>100_bases
GGCTCCCTGATACCGCGCATGTCCCGCAGGCCTCGATCCGCGTGGCGCATGCCGCGCGCTTTCGATTGTCGTGCGCTACC
GTTCGCCCGTTGCGCAGGCA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIQRLSPLEIMIRLVSFPTVSSETNLPLIEWTSEYLSAHGIEHHVWIDPEQPEKAGLYAHVGPKVEGGVVLSGHTDVVPV
EGQDWSSDPFEVVERDGKYFGRGCADMKGFDALALWALVEGNYTDLQRPLQLAFTFDEEIGCTGAPPLIEEMQKYLPKAE
AVIVGEPSMLKAVTGHKGAFAMATHVRGFEVHSSLMHEGVSAVMEAARIVDWANHRNAENRARPQTEVAAMFTPPWTTVH
VGKISGGTAHNITAGDCNFWMDFRVVPGESLADWQAAYEAEIARIEAEMQRVRPEAGITLEKVFSVPGLAPETDGAAETL
VRALTGDNARHVVSYGTEAGHYQVAGYSAVVCGPGDIAQAHQADEFITVAQFEAGTKFMQDLLSRLSA

Sequences:

>Translated_388_residues
MIQRLSPLEIMIRLVSFPTVSSETNLPLIEWTSEYLSAHGIEHHVWIDPEQPEKAGLYAHVGPKVEGGVVLSGHTDVVPV
EGQDWSSDPFEVVERDGKYFGRGCADMKGFDALALWALVEGNYTDLQRPLQLAFTFDEEIGCTGAPPLIEEMQKYLPKAE
AVIVGEPSMLKAVTGHKGAFAMATHVRGFEVHSSLMHEGVSAVMEAARIVDWANHRNAENRARPQTEVAAMFTPPWTTVH
VGKISGGTAHNITAGDCNFWMDFRVVPGESLADWQAAYEAEIARIEAEMQRVRPEAGITLEKVFSVPGLAPETDGAAETL
VRALTGDNARHVVSYGTEAGHYQVAGYSAVVCGPGDIAQAHQADEFITVAQFEAGTKFMQDLLSRLSA
>Mature_388_residues
MIQRLSPLEIMIRLVSFPTVSSETNLPLIEWTSEYLSAHGIEHHVWIDPEQPEKAGLYAHVGPKVEGGVVLSGHTDVVPV
EGQDWSSDPFEVVERDGKYFGRGCADMKGFDALALWALVEGNYTDLQRPLQLAFTFDEEIGCTGAPPLIEEMQKYLPKAE
AVIVGEPSMLKAVTGHKGAFAMATHVRGFEVHSSLMHEGVSAVMEAARIVDWANHRNAENRARPQTEVAAMFTPPWTTVH
VGKISGGTAHNITAGDCNFWMDFRVVPGESLADWQAAYEAEIARIEAEMQRVRPEAGITLEKVFSVPGLAPETDGAAETL
VRALTGDNARHVVSYGTEAGHYQVAGYSAVVCGPGDIAQAHQADEFITVAQFEAGTKFMQDLLSRLSA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=385, Percent_Identity=30.9090909090909, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788816, Length=340, Percent_Identity=24.7058823529412, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42240; Mature: 42240

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQRLSPLEIMIRLVSFPTVSSETNLPLIEWTSEYLSAHGIEHHVWIDPEQPEKAGLYAH
CCCCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCEEEEECCCCCHHCCEEEE
VGPKVEGGVVLSGHTDVVPVEGQDWSSDPFEVVERDGKYFGRGCADMKGFDALALWALVE
ECCCCCCCEEEECCCCEEECCCCCCCCCHHHHHHCCCCHHCCCCCCCCCCCCEEEEEEEC
GNYTDLQRPLQLAFTFDEEIGCTGAPPLIEEMQKYLPKAEAVIVGEPSMLKAVTGHKGAF
CCHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHCCCCCCE
AMATHVRGFEVHSSLMHEGVSAVMEAARIVDWANHRNAENRARPQTEVAAMFTPPWTTVH
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEE
VGKISGGTAHNITAGDCNFWMDFRVVPGESLADWQAAYEAEIARIEAEMQRVRPEAGITL
EEECCCCCCCCEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EKVFSVPGLAPETDGAAETLVRALTGDNARHVVSYGTEAGHYQVAGYSAVVCGPGDIAQA
HHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEECCEEEEEECCCCHHHH
HQADEFITVAQFEAGTKFMQDLLSRLSA
HCCCCEEEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQRLSPLEIMIRLVSFPTVSSETNLPLIEWTSEYLSAHGIEHHVWIDPEQPEKAGLYAH
CCCCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCEEEEECCCCCHHCCEEEE
VGPKVEGGVVLSGHTDVVPVEGQDWSSDPFEVVERDGKYFGRGCADMKGFDALALWALVE
ECCCCCCCEEEECCCCEEECCCCCCCCCHHHHHHCCCCHHCCCCCCCCCCCCEEEEEEEC
GNYTDLQRPLQLAFTFDEEIGCTGAPPLIEEMQKYLPKAEAVIVGEPSMLKAVTGHKGAF
CCHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHCCCCCCE
AMATHVRGFEVHSSLMHEGVSAVMEAARIVDWANHRNAENRARPQTEVAAMFTPPWTTVH
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEE
VGKISGGTAHNITAGDCNFWMDFRVVPGESLADWQAAYEAEIARIEAEMQRVRPEAGITL
EEECCCCCCCCEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EKVFSVPGLAPETDGAAETLVRALTGDNARHVVSYGTEAGHYQVAGYSAVVCGPGDIAQA
HHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEECCEEEEEECCCCHHHH
HQADEFITVAQFEAGTKFMQDLLSRLSA
HCCCCEEEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]