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The map label for this gene is argK [C]

Identifier: 99080511

GI number: 99080511

Start: 718401

End: 719402

Strand: Direct

Name: argK [C]

Synonym: TM1040_0670

Alternate gene names: 99080511

Gene position: 718401-719402 (Clockwise)

Preceding gene: 99080507

Following gene: 99080512

Centisome position: 22.44

GC content: 63.17

Gene sequence:

>1002_bases
ATGGACATCACAGAGCTGAGCAAGAAAATCCTGCAGGCTGACCGAAGGGCGCTGGCCCGGGCGATCACACTGGTCGAAAG
CGCACGCGCCGATCATCGCGCACAGGCAGATGCGCTGTTGTCCGAGCTCGCCAAAAGCGACCGTCAGGCATTGCGGATCG
GGCTCTCCGGGACACCAGGCGTGGGAAAATCCACCTTCATCGAAGCCTTTGGCATGATGTTGATCGAGCAGGGGCTCAGG
GTCGCCGTTCTGGCGGTTGATCCAAGTTCGGCGCGTTCTGGTGGTTCGATCCTTGGCGACAAGACTCGCATGGAGCGGCT
GAGCCGGGAGCGCGCGGCCTTCATTCGCCCCAGCCCCAGCCAAAGCCATCTCGGTGGGGTAGCCCGGCGCACCCGCGATG
CTGTTGCGCTCTGCGAGGCGGCAGGGTTTGATGTTGTGCTGATCGAAACCGTCGGTGTTGGTCAGTCGGAGACCGTCGTC
TCGGAGTTGTCGGACCTGTTCTTGCTCCTGCTTGCGCCTGCGGGCGGGGACGAGCTGCAAGGGGTCAAGCGCGGCATCAT
GGAGATCGCGGACATGATCCTCATCAACAAGGCCGATGGCGATCTGAAGGCGACCGCAACCCGAACCTGTGCCGACTATG
CCGGGGCCTTGCGGCTTTTGCGCAAACGTCCGCAAGATCCCGAGGGCTTTCCCAAGGCGCTCACGGTTTCTGCCATAGAG
GCGGCGGGGCTCGATCAGGCCTGGGAAGAAATTCAGGCGCTTGCCGGGTGGCGACGAGAGAACGGCTTTTGGGACAAGAA
CCGTTCACAACAGGCGCAATACTGGTTCGCAGAGGAAGTCCGGCAGGCCCTCCTGTCACGGTTGCAGACTTCCTGGGCCA
AGTCCCGCATGGCAGACCTTTCGGCGCAGGTCGCGGGTGGGGCGCAAACACCACAGGATGCGGCGCGCGATATGCTCTTG
GGGCTGGGCGTGGGTGATGTGGATCCTTCCGGCGCGCCCTGA

Upstream 100 bases:

>100_bases
CCAGAGCCCTTGTGGGAAGCAGTCAGAGTTTATCCGCCCTCCACTGGACAAGCCCGCCCTGACTACGCCATCAATGCGCG
GCACAGGTAAAGGGCGCGCC

Downstream 100 bases:

>100_bases
AGGAGCGACTCAGGGGCGTAAGCGGCGAAAACCCGGAGGACCAGAAGCCAGGCCCAGGCTTGTAAGCTGCGGCTAAAACT
GTAAAAGCGCGCCAGCGCCA

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDITELSKKILQADRRALARAITLVESARADHRAQADALLSELAKSDRQALRIGLSGTPGVGKSTFIEAFGMMLIEQGLR
VAVLAVDPSSARSGGSILGDKTRMERLSRERAAFIRPSPSQSHLGGVARRTRDAVALCEAAGFDVVLIETVGVGQSETVV
SELSDLFLLLLAPAGGDELQGVKRGIMEIADMILINKADGDLKATATRTCADYAGALRLLRKRPQDPEGFPKALTVSAIE
AAGLDQAWEEIQALAGWRRENGFWDKNRSQQAQYWFAEEVRQALLSRLQTSWAKSRMADLSAQVAGGAQTPQDAARDMLL
GLGVGDVDPSGAP

Sequences:

>Translated_333_residues
MDITELSKKILQADRRALARAITLVESARADHRAQADALLSELAKSDRQALRIGLSGTPGVGKSTFIEAFGMMLIEQGLR
VAVLAVDPSSARSGGSILGDKTRMERLSRERAAFIRPSPSQSHLGGVARRTRDAVALCEAAGFDVVLIETVGVGQSETVV
SELSDLFLLLLAPAGGDELQGVKRGIMEIADMILINKADGDLKATATRTCADYAGALRLLRKRPQDPEGFPKALTVSAIE
AAGLDQAWEEIQALAGWRRENGFWDKNRSQQAQYWFAEEVRQALLSRLQTSWAKSRMADLSAQVAGGAQTPQDAARDMLL
GLGVGDVDPSGAP
>Mature_333_residues
MDITELSKKILQADRRALARAITLVESARADHRAQADALLSELAKSDRQALRIGLSGTPGVGKSTFIEAFGMMLIEQGLR
VAVLAVDPSSARSGGSILGDKTRMERLSRERAAFIRPSPSQSHLGGVARRTRDAVALCEAAGFDVVLIETVGVGQSETVV
SELSDLFLLLLAPAGGDELQGVKRGIMEIADMILINKADGDLKATATRTCADYAGALRLLRKRPQDPEGFPKALTVSAIE
AAGLDQAWEEIQALAGWRRENGFWDKNRSQQAQYWFAEEVRQALLSRLQTSWAKSRMADLSAQVAGGAQTPQDAARDMLL
GLGVGDVDPSGAP

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=329, Percent_Identity=45.5927051671732, Blast_Score=274, Evalue=7e-74,
Organism=Escherichia coli, GI1789285, Length=286, Percent_Identity=47.5524475524476, Blast_Score=265, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI71994271, Length=330, Percent_Identity=43.3333333333333, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71994275, Length=275, Percent_Identity=45.4545454545455, Blast_Score=232, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35691; Mature: 35691

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITELSKKILQADRRALARAITLVESARADHRAQADALLSELAKSDRQALRIGLSGTPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
VGKSTFIEAFGMMLIEQGLRVAVLAVDPSSARSGGSILGDKTRMERLSRERAAFIRPSPS
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
QSHLGGVARRTRDAVALCEAAGFDVVLIETVGVGQSETVVSELSDLFLLLLAPAGGDELQ
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
GVKRGIMEIADMILINKADGDLKATATRTCADYAGALRLLRKRPQDPEGFPKALTVSAIE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AAGLDQAWEEIQALAGWRRENGFWDKNRSQQAQYWFAEEVRQALLSRLQTSWAKSRMADL
HHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAQVAGGAQTPQDAARDMLLGLGVGDVDPSGAP
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDITELSKKILQADRRALARAITLVESARADHRAQADALLSELAKSDRQALRIGLSGTPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
VGKSTFIEAFGMMLIEQGLRVAVLAVDPSSARSGGSILGDKTRMERLSRERAAFIRPSPS
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
QSHLGGVARRTRDAVALCEAAGFDVVLIETVGVGQSETVVSELSDLFLLLLAPAGGDELQ
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
GVKRGIMEIADMILINKADGDLKATATRTCADYAGALRLLRKRPQDPEGFPKALTVSAIE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AAGLDQAWEEIQALAGWRRENGFWDKNRSQQAQYWFAEEVRQALLSRLQTSWAKSRMADL
HHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAQVAGGAQTPQDAARDMLLGLGVGDVDPSGAP
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]