Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 99080386

GI number: 99080386

Start: 578562

End: 579359

Strand: Direct

Name: glpR [H]

Synonym: TM1040_0545

Alternate gene names: 99080386

Gene position: 578562-579359 (Clockwise)

Preceding gene: 99080380

Following gene: 99080387

Centisome position: 18.07

GC content: 61.15

Gene sequence:

>798_bases
ATGCGACGGGGGGAACTCAACGAGCGCCGGGATGCGATTATTCGGTTGTTGTGCGCACAAGACGAGTTGTCCGCGCAGGA
TCTGGCCGCGCGGCTGAATGTGTCTGTCCAGACCATTCGCACCGATTTGCGAGAACTCGATGAGGCGGCCCTGGTGCAAC
GTCGCCACGGCAGGGTCCGGCTTCGGCAGCCCTCGGAGAACATCGGCTACGCCCCGCGGATGAGTGTCGCGCGCAGCGAA
AAGCAACAGATCGCGATGGCGGTAAAACCGATGATAGAAGATGGTAGCCGTGTTGCTTTGGGCACGGGGACCACGGTCGA
GGCCTGCGCGCGTCAGCTGGCCGCCAGCCATAGGGACCTCTTTGTTGCCACCAACAACATTCACGCGGTGATTGCGCTGC
AAGGGGCAAGCGGGGTCTCGGTATCGCTTGCCGGGGGGGCGGTGCGGCTGCGCGATCTGGATTTTGTCGGCGCTGCGAGT
CGCGCGTTTTTTGCCGACTACATGGTCGACATCGCGATTTTTAGTTGCGGCGGTCTTTCCCTTTCCGGGGATGTTTTGGA
CTACAACACGGATGAGATCGCCGCGCGTGAGGCGATTTCAACCTGCGCCACGCGCCGGGTTCTGGTCGTGGATCGAGAAA
AATTCGGGCGTGCTCTACCGTGCCGAAAACACATGATCTGGGACTATGACGTGGTGGTCACGGGGGCTGATTTTCCTCGG
GAAATCATGCGCAAATGCCAAGAAGCCGGGTGCGAGGTTCTGCGTGTCGCCACAGATGAACGCCCGCTGCGCGCCTGA

Upstream 100 bases:

>100_bases
ACGATCATGTGACAGTTTCGCAAATCTATTATTATCTTGCCCGGAGGGCGCTGCTCTTGTTAGGACGCCCGCACGGATTT
TCACTTTCAAAGGAAAGCGA

Downstream 100 bases:

>100_bases
TGCGGCTGGCAGGTTGAGGCCGTTAATCGTTCAAATTTGAATCGATATTTTTGAAAATAATATAATCTTTTCAGATTGTT
GCAGGGGTTTTTGTTAGGGG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRRGELNERRDAIIRLLCAQDELSAQDLAARLNVSVQTIRTDLRELDEAALVQRRHGRVRLRQPSENIGYAPRMSVARSE
KQQIAMAVKPMIEDGSRVALGTGTTVEACARQLAASHRDLFVATNNIHAVIALQGASGVSVSLAGGAVRLRDLDFVGAAS
RAFFADYMVDIAIFSCGGLSLSGDVLDYNTDEIAAREAISTCATRRVLVVDREKFGRALPCRKHMIWDYDVVVTGADFPR
EIMRKCQEAGCEVLRVATDERPLRA

Sequences:

>Translated_265_residues
MRRGELNERRDAIIRLLCAQDELSAQDLAARLNVSVQTIRTDLRELDEAALVQRRHGRVRLRQPSENIGYAPRMSVARSE
KQQIAMAVKPMIEDGSRVALGTGTTVEACARQLAASHRDLFVATNNIHAVIALQGASGVSVSLAGGAVRLRDLDFVGAAS
RAFFADYMVDIAIFSCGGLSLSGDVLDYNTDEIAAREAISTCATRRVLVVDREKFGRALPCRKHMIWDYDVVVTGADFPR
EIMRKCQEAGCEVLRVATDERPLRA
>Mature_265_residues
MRRGELNERRDAIIRLLCAQDELSAQDLAARLNVSVQTIRTDLRELDEAALVQRRHGRVRLRQPSENIGYAPRMSVARSE
KQQIAMAVKPMIEDGSRVALGTGTTVEACARQLAASHRDLFVATNNIHAVIALQGASGVSVSLAGGAVRLRDLDFVGAAS
RAFFADYMVDIAIFSCGGLSLSGDVLDYNTDEIAAREAISTCATRRVLVVDREKFGRALPCRKHMIWDYDVVVTGADFPR
EIMRKCQEAGCEVLRVATDERPLRA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=237, Percent_Identity=33.7552742616034, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI87082344, Length=248, Percent_Identity=27.0161290322581, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789519, Length=257, Percent_Identity=28.7937743190661, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788069, Length=212, Percent_Identity=28.7735849056604, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=26.2096774193548, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI226510968, Length=242, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789170, Length=214, Percent_Identity=27.5700934579439, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787063, Length=233, Percent_Identity=25.7510729613734, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29143; Mature: 29143

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRGELNERRDAIIRLLCAQDELSAQDLAARLNVSVQTIRTDLRELDEAALVQRRHGRVR
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEE
LRQPSENIGYAPRMSVARSEKQQIAMAVKPMIEDGSRVALGTGTTVEACARQLAASHRDL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEE
FVATNNIHAVIALQGASGVSVSLAGGAVRLRDLDFVGAASRAFFADYMVDIAIFSCGGLS
EEEECCEEEEEEEECCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCE
LSGDVLDYNTDEIAAREAISTCATRRVLVVDREKFGRALPCRKHMIWDYDVVVTGADFPR
ECCCEECCCCHHHHHHHHHHHHHHCEEEEEEHHHHCCCCCCCCCEEEEEEEEEECCCCHH
EIMRKCQEAGCEVLRVATDERPLRA
HHHHHHHHCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MRRGELNERRDAIIRLLCAQDELSAQDLAARLNVSVQTIRTDLRELDEAALVQRRHGRVR
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEE
LRQPSENIGYAPRMSVARSEKQQIAMAVKPMIEDGSRVALGTGTTVEACARQLAASHRDL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEE
FVATNNIHAVIALQGASGVSVSLAGGAVRLRDLDFVGAASRAFFADYMVDIAIFSCGGLS
EEEECCEEEEEEEECCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCE
LSGDVLDYNTDEIAAREAISTCATRRVLVVDREKFGRALPCRKHMIWDYDVVVTGADFPR
ECCCEECCCCHHHHHHHHHHHHHHCEEEEEEHHHHCCCCCCCCCEEEEEEEEEECCCCHH
EIMRKCQEAGCEVLRVATDERPLRA
HHHHHHHHCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]