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The map label for this gene is dadA [H]

Identifier: 99080196

GI number: 99080196

Start: 360576

End: 361823

Strand: Direct

Name: dadA [H]

Synonym: TM1040_0355

Alternate gene names: 99080196

Gene position: 360576-361823 (Clockwise)

Preceding gene: 99080193

Following gene: 99080197

Centisome position: 11.26

GC content: 61.94

Gene sequence:

>1248_bases
ATGGCAACTCAGCATATTGTTGTGGTTGGTGCAGGCATCATGGGGGCCGCGAGCGCCATCTGGCTGCGCCGGGCGGGGCT
GGAGGTGACGCTGGTGGACAAGGGGCGGCCCGGCATGGGGGCCTCTTATGGCAATGCCTGTATTCTGGCGCGTTGCGCGA
TGGTTCCTGTGACGACACCGGGGCTGATCGCGAAGGGGCCAAAGTATCTGTTGGACCCGAACTTTCCGCTCTATCTGCGG
TGGTCCTATTTGCCCCGTCTGTTGCCCTGGCTTGGGCGCTATCTGAAACACGCAAATGATCAGGACACCCGGCGTATCTC
GCAAGGGCTCGCGGGGATTGTGGGCGACAGTGTCGAGCAGCACAAAGCGCTCACCGAAGGGATGCCTGCGGCCAAATGGA
TCCAGGACAGCGATTACAACTTTGTCTACCGCGACCGCGCGGCCTTTGAGGCGGAGTCTTATGTGTGGTCGCTTAGGCGC
GAGGCAGGGTTTGAGCCCGAGATCATTGAAGGCGATGACGTCCACGCGCGCGAGCCGATCCTGTCGCGGGACATGCGGCT
TTTGGCGGTCAACAAGGACCACGGCTATATCCTCAACCCCGGCAACTATGTGCAGGATCTGGTGCGCCAGCTCGAGGAGA
TGGGCGGGCGGTTTGTTCAGGCCGAAGTGAAGGATTTTGACCTCATGGGAGGGCAGATCACCGCGGTGGACACCGATCAG
GGGCGCATCGCCTGTGATCGGGCGGTGCTCTCGGCGGGGGTCTGGTCGGCGGCGCTTATGAAGCGGCTCGGGCTCGACGT
GCCGCTGGAGGCAGAGCGCGGCTATCATATCGTCTTCAAGGACCCAAGCCAGCTGCCAACCGCGCCGATGATGCTGACCG
AAGGCAAATTCGTGGCCACGCCGATGGATCAGGGGCTGCGCTGTGCGGGCATCGTGGAGTTTGGCGGGCTGAGCGATGTG
AAGTCCAAGAAGCCGCTTGAGATGCTGCGCCGCACCGTCGCGCGCACATTCCCGAACCTCAGTCACTCTGCCGAGGAAGA
ATGGCTGGGCTTTCGCCCCGCCCCTTCAGACAGCCTGCCGCTTATTGGTGAAGTGCGCGGCAGCGGTGTCTTTACCGCTT
TTGGGCACCATCACATTGGGTTGACAGGCGGGCCCAAGACAGGCCGACTGGTCGCGGATATGATCACGGGCAACTGGCCC
AATGCCGATACCAGCGCCTTTGATCCAATGCGCTTTGCAACGCAATAA

Upstream 100 bases:

>100_bases
CGGGTACATAAGTTTTGATGATGCTCTCATGATCAAATAGTATTTGAAATGATGATCTATTGTCGACAGTCTCGCAGGGA
ACAAGGTTTGGGGACGTGAG

Downstream 100 bases:

>100_bases
CAAGAAACGAAAAAACGAACCAACACGGGAGACAAATCAATGACCAAAATGACGCTCAAGACCACTGTTGCCGGCGCTGC
GCTGGTGCTTGCAGCCGGGG

Product: D-amino-acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MATQHIVVVGAGIMGAASAIWLRRAGLEVTLVDKGRPGMGASYGNACILARCAMVPVTTPGLIAKGPKYLLDPNFPLYLR
WSYLPRLLPWLGRYLKHANDQDTRRISQGLAGIVGDSVEQHKALTEGMPAAKWIQDSDYNFVYRDRAAFEAESYVWSLRR
EAGFEPEIIEGDDVHAREPILSRDMRLLAVNKDHGYILNPGNYVQDLVRQLEEMGGRFVQAEVKDFDLMGGQITAVDTDQ
GRIACDRAVLSAGVWSAALMKRLGLDVPLEAERGYHIVFKDPSQLPTAPMMLTEGKFVATPMDQGLRCAGIVEFGGLSDV
KSKKPLEMLRRTVARTFPNLSHSAEEEWLGFRPAPSDSLPLIGEVRGSGVFTAFGHHHIGLTGGPKTGRLVADMITGNWP
NADTSAFDPMRFATQ

Sequences:

>Translated_415_residues
MATQHIVVVGAGIMGAASAIWLRRAGLEVTLVDKGRPGMGASYGNACILARCAMVPVTTPGLIAKGPKYLLDPNFPLYLR
WSYLPRLLPWLGRYLKHANDQDTRRISQGLAGIVGDSVEQHKALTEGMPAAKWIQDSDYNFVYRDRAAFEAESYVWSLRR
EAGFEPEIIEGDDVHAREPILSRDMRLLAVNKDHGYILNPGNYVQDLVRQLEEMGGRFVQAEVKDFDLMGGQITAVDTDQ
GRIACDRAVLSAGVWSAALMKRLGLDVPLEAERGYHIVFKDPSQLPTAPMMLTEGKFVATPMDQGLRCAGIVEFGGLSDV
KSKKPLEMLRRTVARTFPNLSHSAEEEWLGFRPAPSDSLPLIGEVRGSGVFTAFGHHHIGLTGGPKTGRLVADMITGNWP
NADTSAFDPMRFATQ
>Mature_414_residues
ATQHIVVVGAGIMGAASAIWLRRAGLEVTLVDKGRPGMGASYGNACILARCAMVPVTTPGLIAKGPKYLLDPNFPLYLRW
SYLPRLLPWLGRYLKHANDQDTRRISQGLAGIVGDSVEQHKALTEGMPAAKWIQDSDYNFVYRDRAAFEAESYVWSLRRE
AGFEPEIIEGDDVHAREPILSRDMRLLAVNKDHGYILNPGNYVQDLVRQLEEMGGRFVQAEVKDFDLMGGQITAVDTDQG
RIACDRAVLSAGVWSAALMKRLGLDVPLEAERGYHIVFKDPSQLPTAPMMLTEGKFVATPMDQGLRCAGIVEFGGLSDVK
SKKPLEMLRRTVARTFPNLSHSAEEEWLGFRPAPSDSLPLIGEVRGSGVFTAFGHHHIGLTGGPKTGRLVADMITGNWPN
ADTSAFDPMRFATQ

Specific function: Oxidative deamination of D-amino acids [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787438, Length=408, Percent_Identity=23.7745098039216, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 45576; Mature: 45445

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQHIVVVGAGIMGAASAIWLRRAGLEVTLVDKGRPGMGASYGNACILARCAMVPVTTP
CCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEHHHHCCCCCCC
GLIAKGPKYLLDPNFPLYLRWSYLPRLLPWLGRYLKHANDQDTRRISQGLAGIVGDSVEQ
CHHCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHH
HKALTEGMPAAKWIQDSDYNFVYRDRAAFEAESYVWSLRREAGFEPEIIEGDDVHAREPI
HHHHHCCCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCH
LSRDMRLLAVNKDHGYILNPGNYVQDLVRQLEEMGGRFVQAEVKDFDLMGGQITAVDTDQ
HHCCEEEEEEECCCCEEECCCHHHHHHHHHHHHHCCEEEEEEHHHHCCCCCEEEEEECCC
GRIACDRAVLSAGVWSAALMKRLGLDVPLEAERGYHIVFKDPSQLPTAPMMLTEGKFVAT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCCCCCEEEECCCEEEC
PMDQGLRCAGIVEFGGLSDVKSKKPLEMLRRTVARTFPNLSHSAEEEWLGFRPAPSDSLP
CCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCC
LIGEVRGSGVFTAFGHHHIGLTGGPKTGRLVADMITGNWPNADTSAFDPMRFATQ
EEEEECCCEEEEECCCEEEEECCCCCCCCEEEEHHCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
ATQHIVVVGAGIMGAASAIWLRRAGLEVTLVDKGRPGMGASYGNACILARCAMVPVTTP
CCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEHHHHCCCCCCC
GLIAKGPKYLLDPNFPLYLRWSYLPRLLPWLGRYLKHANDQDTRRISQGLAGIVGDSVEQ
CHHCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHH
HKALTEGMPAAKWIQDSDYNFVYRDRAAFEAESYVWSLRREAGFEPEIIEGDDVHAREPI
HHHHHCCCCHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCH
LSRDMRLLAVNKDHGYILNPGNYVQDLVRQLEEMGGRFVQAEVKDFDLMGGQITAVDTDQ
HHCCEEEEEEECCCCEEECCCHHHHHHHHHHHHHCCEEEEEEHHHHCCCCCEEEEEECCC
GRIACDRAVLSAGVWSAALMKRLGLDVPLEAERGYHIVFKDPSQLPTAPMMLTEGKFVAT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCCCCCEEEECCCEEEC
PMDQGLRCAGIVEFGGLSDVKSKKPLEMLRRTVARTFPNLSHSAEEEWLGFRPAPSDSLP
CCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCC
LIGEVRGSGVFTAFGHHHIGLTGGPKTGRLVADMITGNWPNADTSAFDPMRFATQ
EEEEECCCEEEEECCCEEEEECCCCCCCCEEEEHHCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA