BacMap

Definition	Ruegeria sp. TM1040, complete genome.
Accession	NC_008044
Length	3,200,938

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The map label for this gene is fixR [H]

Identifier: 99080143

GI number: 99080143

Start: 308089

End: 308820

Strand: Direct

Name: fixR [H]

Synonym: TM1040_0302

Alternate gene names: 99080143

Gene position: 308089-308820 (Clockwise)

Preceding gene: 99080138

Following gene: 99080151

Centisome position: 9.62

GC content: 63.52

Gene sequence:

>732_bases
ATGCGTCGCAAAACCCTGCTCTTGACCGGAGCCAGCCGGGGCATCGGCCATGCCACCGTGCGCCGGTTCAACGCCGAGGG
ATGGCGGGTGATTACCTGTTCACGCCAACCGTTTCCCAAGGAATGCCCCTGGGGCGGCGGCGAGGAAAACCATGTGCAGC
TGGATCTGTCGGACCCCTCGGATACCATCAATGCGGTTGGTGTCATTCAGGAACGTCTGGAGGACGGCAGGCTTGACGCT
TTGGTCAACAACGCGGGTATCTCGCCCAAGGGCCCCGATGGCGAGCGGCTGAGCACGCTCAACACCGATCTGATGGATTG
GGCCAAGGTGTTTCACGTCAATTTCTTTGCCTCGGTGGTGCTGGCGCGCGGCCTGCGCGAGGAACTGGCCGCGGCCAAGG
GGGCAGTGGTCAATGTGACCTCGATTGCGGGCAGTCGGGTGCATCCTTTTGCGGGGGCGGCCTATGCCACCTCAAAGGCG
GCGCTGGCGGCGCTGACGCGCGAGATGGCGCATGACTTCGGGCCGATGGGCGTGCGCGTAAATGCGATTGCGCCGGGCGA
GGTGGAGACCTCGATCCTCAGCCCTGGCACCGACAAGATCGTGGAAAAGCTGCCGATGCGCAGGCTTGGCCAGCCCTCCG
AGGTGGCGGATGCGATCTATTTCCTGTGCTCGGAGAAGAGCAGCTATATTTCCGGCACCGAGATCGAGGTGAACGGCGCG
CAGCACGTCTGA

Upstream 100 bases:

>100_bases
CGCATGGTGGTGCAGGGCGCCCTCTGCTGTGCCGGATGCCATTGCCGTGGCGGCACGGGCTGCTAAGGTCTGCGCAGCAT
CAGCCGTGAGAGGACAGCCC

Downstream 100 bases:

>100_bases
ACGCCGCAGGATTGGCCCGGCCTTGTGCGCAAAGCCGGGCCGAGGGTCAGCTGACCACGCGCTTGAGGCGGGGCAGGTTC
GACAGGATCAGCACATCCAG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRRKTLLLTGASRGIGHATVRRFNAEGWRVITCSRQPFPKECPWGGGEENHVQLDLSDPSDTINAVGVIQERLEDGRLDA
LVNNAGISPKGPDGERLSTLNTDLMDWAKVFHVNFFASVVLARGLREELAAAKGAVVNVTSIAGSRVHPFAGAAYATSKA
ALAALTREMAHDFGPMGVRVNAIAPGEVETSILSPGTDKIVEKLPMRRLGQPSEVADAIYFLCSEKSSYISGTEIEVNGA
QHV

Sequences:

>Translated_243_residues
MRRKTLLLTGASRGIGHATVRRFNAEGWRVITCSRQPFPKECPWGGGEENHVQLDLSDPSDTINAVGVIQERLEDGRLDA
LVNNAGISPKGPDGERLSTLNTDLMDWAKVFHVNFFASVVLARGLREELAAAKGAVVNVTSIAGSRVHPFAGAAYATSKA
ALAALTREMAHDFGPMGVRVNAIAPGEVETSILSPGTDKIVEKLPMRRLGQPSEVADAIYFLCSEKSSYISGTEIEVNGA
QHV
>Mature_243_residues
MRRKTLLLTGASRGIGHATVRRFNAEGWRVITCSRQPFPKECPWGGGEENHVQLDLSDPSDTINAVGVIQERLEDGRLDA
LVNNAGISPKGPDGERLSTLNTDLMDWAKVFHVNFFASVVLARGLREELAAAKGAVVNVTSIAGSRVHPFAGAAYATSKA
ALAALTREMAHDFGPMGVRVNAIAPGEVETSILSPGTDKIVEKLPMRRLGQPSEVADAIYFLCSEKSSYISGTEIEVNGA
QHV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=32.3076923076923, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=33.4661354581673, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=29.3893129770992, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=29.1666666666667, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.5220883534137, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=28.4518828451883, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=28.3333333333333, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4504503, Length=226, Percent_Identity=30.0884955752212, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI119392083, Length=193, Percent_Identity=31.6062176165803, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI150247226, Length=197, Percent_Identity=30.4568527918782, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI66933014, Length=174, Percent_Identity=26.4367816091954, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=211, Percent_Identity=30.8056872037915, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=23.9700374531835, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI126723750, Length=151, Percent_Identity=31.7880794701987, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40548397, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI214010158, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI214010156, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI22758144, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.413612565445, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI223718074, Length=235, Percent_Identity=30.6382978723404, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.4324324324324, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=35.3658536585366, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=31.6, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=29.9595141700405, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788459, Length=198, Percent_Identity=33.8383838383838, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.3643724696356, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=30.5555555555556, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=26.0536398467433, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789208, Length=178, Percent_Identity=29.7752808988764, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=29.5019157088123, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=26.984126984127, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786701, Length=232, Percent_Identity=30.6034482758621, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30.8, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=33.984375, Blast_Score=106, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=32.03125, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=34.7328244274809, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=35.3383458646617, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=33.955223880597, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=30.952380952381, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=32.5581395348837, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=34.4827586206897, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=33.587786259542, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=32.9411764705882, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=31.5175097276265, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=29.3893129770992, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=32.5581395348837, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=29.9212598425197, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=31.1284046692607, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=30.2681992337165, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=28.6821705426357, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=30.9160305343511, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=28.1853281853282, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=25.3112033195021, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=26.953125, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=183, Percent_Identity=31.1475409836066, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=196, Percent_Identity=35.2040816326531, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324126, Length=139, Percent_Identity=28.7769784172662, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=33.4645669291339, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=30.8943089430894, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24644337, Length=214, Percent_Identity=36.4485981308411, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=31.5384615384615, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=32.8063241106719, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=32.421875, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=28.6259541984733, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26049; Mature: 26049

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKTLLLTGASRGIGHATVRRFNAEGWRVITCSRQPFPKECPWGGGEENHVQLDLSDPS
CCCEEEEEECCCCCCCHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCC
DTINAVGVIQERLEDGRLDALVNNAGISPKGPDGERLSTLNTDLMDWAKVFHVNFFASVV
HHHHHHHHHHHHHHCCCHHHHECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LARGLREELAAAKGAVVNVTSIAGSRVHPFAGAAYATSKAALAALTREMAHDFGPMGVRV
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
NAIAPGEVETSILSPGTDKIVEKLPMRRLGQPSEVADAIYFLCSEKSSYISGTEIEVNGA
EEECCCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCC
QHV
CCC
>Mature Secondary Structure
MRRKTLLLTGASRGIGHATVRRFNAEGWRVITCSRQPFPKECPWGGGEENHVQLDLSDPS
CCCEEEEEECCCCCCCHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCC
DTINAVGVIQERLEDGRLDALVNNAGISPKGPDGERLSTLNTDLMDWAKVFHVNFFASVV
HHHHHHHHHHHHHHCCCHHHHECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LARGLREELAAAKGAVVNVTSIAGSRVHPFAGAAYATSKAALAALTREMAHDFGPMGVRV
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
NAIAPGEVETSILSPGTDKIVEKLPMRRLGQPSEVADAIYFLCSEKSSYISGTEIEVNGA
EEECCCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCC
QHV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3313281; 11157954; 12597275 [H]