Click here to switch to the map view.

The map label for this gene is aphA [H]

Identifier: 99079978

GI number: 99079978

Start: 151103

End: 152278

Strand: Reverse

Name: aphA [H]

Synonym: TM1040_0137

Alternate gene names: 99079978

Gene position: 152278-151103 (Counterclockwise)

Preceding gene: 99079979

Following gene: 99079977

Centisome position: 4.76

GC content: 52.98

Gene sequence:

>1176_bases
ATGACAATGTCGATGCTCGAGAGTGAGGTCACAGAGGCCTGGGCCGAACAATACGAAACCGCTTTTGTGACATATTGCAA
CACCGGCTCCGAGGAGGCTTTGATCGAAGCATATGCCTTTGCCCGGGAAGGTCTTGCTGCCAGCATGACCCTCGCAGTTT
TTGCGTGTCTCCATCATGCAGCATTTTTCAAGCTTCTCGAGCAATCCGGTCCGGGGAACAATCTTTATGAACGCGCATTG
GACTTTTATCTCGAAGGGGTCTCAGTGTTCGATATGGCCATCCATGGGTACCAAAACAATGTTGCGCGCCTCAAAGAAGA
AGTCACAGAGCGACGGCGCATAGAGGAAGATCTGCGCGCCGCCACCTTTGAGCTGTCTCGACAACGCAGCGACCTCGACA
TTCAAGTTCGCCAACGCACCGCAGAGTTGCGAGAGAGGGCGGAGGAGCTGGAGCAGTCCAATCGCTTGCTCCTCCAGACC
AACAAGGAGACATCAGAGTTTTCCTACGCGCTGTCTCATGACCTCAAATCTCCGATCAACACGATAGGCATGCTTCTTGA
TGCTATCCGAGAGGAACTGCCACCAGACAGCGAATCCGAATGCGCAGACCTCGTATCGGATGCATCGCTGACAGCAGAGC
GCATGAAGCGTCTGATCGATGATGTATTGCAATACTCGCAAGTCGTTGGAAACACGCTTGAACGGGAATTGGTCGACATG
AGCCAACTGTGCCAAGACGCCCTGTCTGACATGCGCCACGCGATCGACGAAGCACAAGCCGATATCTCATGCTCCCATCT
CCCGGTCGTGCGCGGAAGCGCGTTTCAACTGGCTATCATGCTGCGAAATTTCCTATCAAACGCACTGACCTACCGCGATG
CCTCTCGCCCCTTAAGGGTCGAGATCTCAGCGGGACCCACCGCAGAGACTGGCCGGGTTTTGATTTCGATTGCCGACAAC
GGCATCGGCATGCCACCAGACTGCCATGCCCGGATTTTTAACCTGTTCACAAGGCTTCACACTTACAGCGATTTTGAAGG
ATCCGGCATTGGGTTAGCATTATGTAAACGCGTGGCAAATAATCATAACAGTGACATCGAAGTCGAATCCGTCGAGGGGC
AAGGGACTATATTCAGCTTCTCTATCGAAAGCGAGGAGGTTGATACATGGCATTAA

Upstream 100 bases:

>100_bases
ACCAAGCCCCGCGTGAGTTTGCCGATAGCTGCTTCAATGACTTCGGCCGTGACAATGATGATCGGACGTTGGCGACCTTC
TCCTGGACACAGGAGGGGAC

Downstream 100 bases:

>100_bases
CCAAGATCTATGCAATCGACGACGACATGTTGGACCGCAAGATGCTTCAGCGTGTGGTCGAGCGCTCTGGCAAGGTCAAT
TCGCTCGAACTCTACTCTTA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTMSMLESEVTEAWAEQYETAFVTYCNTGSEEALIEAYAFAREGLAASMTLAVFACLHHAAFFKLLEQSGPGNNLYERAL
DFYLEGVSVFDMAIHGYQNNVARLKEEVTERRRIEEDLRAATFELSRQRSDLDIQVRQRTAELRERAEELEQSNRLLLQT
NKETSEFSYALSHDLKSPINTIGMLLDAIREELPPDSESECADLVSDASLTAERMKRLIDDVLQYSQVVGNTLERELVDM
SQLCQDALSDMRHAIDEAQADISCSHLPVVRGSAFQLAIMLRNFLSNALTYRDASRPLRVEISAGPTAETGRVLISIADN
GIGMPPDCHARIFNLFTRLHTYSDFEGSGIGLALCKRVANNHNSDIEVESVEGQGTIFSFSIESEEVDTWH

Sequences:

>Translated_391_residues
MTMSMLESEVTEAWAEQYETAFVTYCNTGSEEALIEAYAFAREGLAASMTLAVFACLHHAAFFKLLEQSGPGNNLYERAL
DFYLEGVSVFDMAIHGYQNNVARLKEEVTERRRIEEDLRAATFELSRQRSDLDIQVRQRTAELRERAEELEQSNRLLLQT
NKETSEFSYALSHDLKSPINTIGMLLDAIREELPPDSESECADLVSDASLTAERMKRLIDDVLQYSQVVGNTLERELVDM
SQLCQDALSDMRHAIDEAQADISCSHLPVVRGSAFQLAIMLRNFLSNALTYRDASRPLRVEISAGPTAETGRVLISIADN
GIGMPPDCHARIFNLFTRLHTYSDFEGSGIGLALCKRVANNHNSDIEVESVEGQGTIFSFSIESEEVDTWH
>Mature_390_residues
TMSMLESEVTEAWAEQYETAFVTYCNTGSEEALIEAYAFAREGLAASMTLAVFACLHHAAFFKLLEQSGPGNNLYERALD
FYLEGVSVFDMAIHGYQNNVARLKEEVTERRRIEEDLRAATFELSRQRSDLDIQVRQRTAELRERAEELEQSNRLLLQTN
KETSEFSYALSHDLKSPINTIGMLLDAIREELPPDSESECADLVSDASLTAERMKRLIDDVLQYSQVVGNTLERELVDMS
QLCQDALSDMRHAIDEAQADISCSHLPVVRGSAFQLAIMLRNFLSNALTYRDASRPLRVEISAGPTAETGRVLISIADNG
IGMPPDCHARIFNLFTRLHTYSDFEGSGIGLALCKRVANNHNSDIEVESVEGQGTIFSFSIESEEVDTWH

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=25.6704980842912, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=25.2918287937743, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=28.5140562248996, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994928, Length=275, Percent_Identity=26.1818181818182, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789149, Length=291, Percent_Identity=23.3676975945017, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=25.8928571428571, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43842; Mature: 43710

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSMLESEVTEAWAEQYETAFVTYCNTGSEEALIEAYAFAREGLAASMTLAVFACLHHA
CCHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AFFKLLEQSGPGNNLYERALDFYLEGVSVFDMAIHGYQNNVARLKEEVTERRRIEEDLRA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATFELSRQRSDLDIQVRQRTAELRERAEELEQSNRLLLQTNKETSEFSYALSHDLKSPIN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
TIGMLLDAIREELPPDSESECADLVSDASLTAERMKRLIDDVLQYSQVVGNTLERELVDM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLCQDALSDMRHAIDEAQADISCSHLPVVRGSAFQLAIMLRNFLSNALTYRDASRPLRV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
EISAGPTAETGRVLISIADNGIGMPPDCHARIFNLFTRLHTYSDFEGSGIGLALCKRVAN
EECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NHNSDIEVESVEGQGTIFSFSIESEEVDTWH
CCCCCEEEEEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TMSMLESEVTEAWAEQYETAFVTYCNTGSEEALIEAYAFAREGLAASMTLAVFACLHHA
CHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AFFKLLEQSGPGNNLYERALDFYLEGVSVFDMAIHGYQNNVARLKEEVTERRRIEEDLRA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATFELSRQRSDLDIQVRQRTAELRERAEELEQSNRLLLQTNKETSEFSYALSHDLKSPIN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
TIGMLLDAIREELPPDSESECADLVSDASLTAERMKRLIDDVLQYSQVVGNTLERELVDM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLCQDALSDMRHAIDEAQADISCSHLPVVRGSAFQLAIMLRNFLSNALTYRDASRPLRV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
EISAGPTAETGRVLISIADNGIGMPPDCHARIFNLFTRLHTYSDFEGSGIGLALCKRVAN
EECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NHNSDIEVESVEGQGTIFSFSIESEEVDTWH
CCCCCEEEEEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]