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The map label for this gene is gst [C]

Identifier: 99079883

GI number: 99079883

Start: 44852

End: 45442

Strand: Reverse

Name: gst [C]

Synonym: TM1040_0042

Alternate gene names: 99079883

Gene position: 45442-44852 (Counterclockwise)

Preceding gene: 99079884

Following gene: 99079880

Centisome position: 1.42

GC content: 60.07

Gene sequence:

>591_bases
ATGTATCAAGTGATTGGCGTTCCCAAGACCCGCGCGTTCCGGGTGTTGTGGACTCTCGAGGAGCTGGGGCAGAGCTACGA
TCTGGTCCCGGCACAACCCCAAAGCGCGGAGGCGCGTGCTGCCAATCCTTCGGGCAAGGTCCCGGCTCTGGTTGAGGACG
GCGAGAGCATCACCGATTCTGTGGCGATCATCACCTATCTGGCCGACAAACATGGCGCTCTGACCGCACCTGCAGGCACT
TTGGCGCGCGCAAGACAGGACGCCATCACCAATATGGTGATCGACGAGATGGACGCGATCCTCTGGACGGCAGCGCGTCA
CAGCTTCATTCTGCCCGAAGACCGCCGGGTGCCAGAGATCAAAGACTCTCTTAGGTGGGAATTCGCCAATTCCATCAAAC
GCATCAACGCGCAGCTCAGCGGGGAATTTGTCGCTGGCGATCAGTTCACGATCGCAGATGTTTTGATGACGCATTGCCTC
AACTGGGCGCGTGGCGCGAAGTTTGACGTCGAAGGCGATGCGGTGCTGGACTATGGCAAGCGCATGCGCGCGCGACCGGC
ATTTCAGCGCGTGGCGGAACTCGCCAAGTAG

Upstream 100 bases:

>100_bases
TGCGATGCTCGCCCGCGCACGTTGAGCGCAGCTCAAGCTGATGCTTGACCTCTCTCGGATTGGCGGCAACCCTGCGCGGC
AACAAACGAGGAGATTTCCA

Downstream 100 bases:

>100_bases
CGCGCCGCCGCTTGCCCTGCCCAACGGCCGGTCGCAAAGCAGGCAGTCAAGAGATACCCTCCCGTTGGCGCATCCCAATC
AAGCATCTCTCCGGCGCAAA

Product: glutathione S-transferase-like

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase; Glutathione S-Transferase Family Protein; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione S-Transferase N-Terminal Domain; Glutathionine S-Transferase; Glutathione S-Transferase Domain; Glutathione S-Transferase Like Protein

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MYQVIGVPKTRAFRVLWTLEELGQSYDLVPAQPQSAEARAANPSGKVPALVEDGESITDSVAIITYLADKHGALTAPAGT
LARARQDAITNMVIDEMDAILWTAARHSFILPEDRRVPEIKDSLRWEFANSIKRINAQLSGEFVAGDQFTIADVLMTHCL
NWARGAKFDVEGDAVLDYGKRMRARPAFQRVAELAK

Sequences:

>Translated_196_residues
MYQVIGVPKTRAFRVLWTLEELGQSYDLVPAQPQSAEARAANPSGKVPALVEDGESITDSVAIITYLADKHGALTAPAGT
LARARQDAITNMVIDEMDAILWTAARHSFILPEDRRVPEIKDSLRWEFANSIKRINAQLSGEFVAGDQFTIADVLMTHCL
NWARGAKFDVEGDAVLDYGKRMRARPAFQRVAELAK
>Mature_196_residues
MYQVIGVPKTRAFRVLWTLEELGQSYDLVPAQPQSAEARAANPSGKVPALVEDGESITDSVAIITYLADKHGALTAPAGT
LARARQDAITNMVIDEMDAILWTAARHSFILPEDRRVPEIKDSLRWEFANSIKRINAQLSGEFVAGDQFTIADVLMTHCL
NWARGAKFDVEGDAVLDYGKRMRARPAFQRVAELAK

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 21655; Mature: 21655

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQVIGVPKTRAFRVLWTLEELGQSYDLVPAQPQSAEARAANPSGKVPALVEDGESITDS
CCEECCCCCCHHHHHEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHH
VAIITYLADKHGALTAPAGTLARARQDAITNMVIDEMDAILWTAARHSFILPEDRRVPEI
HHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCHH
KDSLRWEFANSIKRINAQLSGEFVAGDQFTIADVLMTHCLNWARGAKFDVEGDAVLDYGK
HHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RMRARPAFQRVAELAK
HHHCCHHHHHHHHHCC
>Mature Secondary Structure
MYQVIGVPKTRAFRVLWTLEELGQSYDLVPAQPQSAEARAANPSGKVPALVEDGESITDS
CCEECCCCCCHHHHHEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHH
VAIITYLADKHGALTAPAGTLARARQDAITNMVIDEMDAILWTAARHSFILPEDRRVPEI
HHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCHH
KDSLRWEFANSIKRINAQLSGEFVAGDQFTIADVLMTHCLNWARGAKFDVEGDAVLDYGK
HHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RMRARPAFQRVAELAK
HHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA