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The map label for this gene is sdhB [H]

Identifier: 94995353

GI number: 94995353

Start: 1911022

End: 1911699

Strand: Direct

Name: sdhB [H]

Synonym: MGAS10750_Spy1957

Alternate gene names: 94995353

Gene position: 1911022-1911699 (Clockwise)

Preceding gene: 94995344

Following gene: 94995354

Centisome position: 98.65

GC content: 35.84

Gene sequence:

>678_bases
TTGCCTATGAATACACAAAAATTTCAATCAGTTTTTGACATCATTGGGCCAGTAATGATTGGTCCATCAAGTAGTCACAC
AGCTGGTGCCGTCAGAATTGGTAAGGTAGTCCATTCCATCTTTGGAGATATTCCTGATGAAGTGACGTTTCACCTTTATA
ATTCATTTGCTAAAACCTACAGAGGACATGGTACTGATAAGGCTCTTGTTGCAGGAATTATGGGTATGGATACTGATAAT
CCTGATATTAAAAATTCTCTAGAAATTGCTCATCAAAAAGGGATAAAAATCTATTGGGATATCTTAAAAGATAGTAATGC
TCCCCATCCCAATACTGTTAAAATCAGTGTCAAAAAAGCTGACAAAACACTTAGTGTTACTGGTGTTTCAATTGGAGGAG
GAAACATTCAAGTAACAGAACTAAATGGTTTTTCTGTCTCGTTATCCATGAATACTCCTACTATAGTTACTGTACACAAA
GATATTCCTGGAATGATCGCAAAGGTAACTGATATCCTATCTTCCAATAATATTAATATCGCCACAATGAATGTTACACG
TGAATCCGCTGGTGAAAAAGCTACTATGATTATAGAAGTCGATTCTAGAGAGTGCCAAGAAGCAGCCAACCAAATTGCAA
AAATTCCTCATATTTATAATGTCAACTTCTTTGACTAG

Upstream 100 bases:

>100_bases
ATTACTCAATAATTTTTTATTATAAAAATAATTTTTTATAATTATATTGCTGTTTTTTGATATTTTTTTGTTATAATAAA
CATAGAAATAAAAAACGGAG

Downstream 100 bases:

>100_bases
AAAGGAAAGCTATGTTTTATACTATTGAAGAACTTGTCAAACAAGCTGACCAACAATTTAATGGAAATATTGCTGAACTC
ATGATTGCCACGGAAGTGGA

Product: L-serinedehydratase beta subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MPMNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPDEVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDN
PDIKNSLEIAHQKGIKIYWDILKDSNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHK
DIPGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYNVNFFD

Sequences:

>Translated_225_residues
MPMNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPDEVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDN
PDIKNSLEIAHQKGIKIYWDILKDSNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHK
DIPGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYNVNFFD
>Mature_224_residues
PMNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPDEVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNP
DIKNSLEIAHQKGIKIYWDILKDSNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKD
IPGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYNVNFFD

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR004643
- InterPro:   IPR005131 [H]

Pfam domain/function: PF01842 ACT; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 24354; Mature: 24223

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPDEVTFHLYNSFAKTY
CCCCHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKDSNAPHPNTVKISVKKA
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEEEC
DKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDIPGMIAKVTDILSSNNINI
CCEEEEEEEEECCCEEEEEEECCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCEE
ATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYNVNFFD
EEEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHCCEEEEEEECC
>Mature Secondary Structure 
PMNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPDEVTFHLYNSFAKTY
CCCHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKDSNAPHPNTVKISVKKA
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEEEC
DKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDIPGMIAKVTDILSSNNINI
CCEEEEEEEEECCCEEEEEEECCEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCCEE
ATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYNVNFFD
EEEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]