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The map label for this gene is argS [H]

Identifier: 94995321

GI number: 94995321

Start: 1880385

End: 1882076

Strand: Direct

Name: argS [H]

Synonym: MGAS10750_Spy1925

Alternate gene names: 94995321

Gene position: 1880385-1882076 (Clockwise)

Preceding gene: 94995317

Following gene: 94995322

Centisome position: 97.07

GC content: 40.96

Gene sequence:

>1692_bases
ATGGATACTAAAACTCTAATCGCAAGTGAAATAGCTAAAGTTGTTCCAGAATTAGAACAAGATGCTATTTTTAACTTGCT
TGAAACCCCAAAAAATTCTGATATGGGAGACCTTGCCTTTCCAGCTTTTAGCTTAGCAAAAGTCCTTCGCAAAGCCCCTC
AAATGATTGCTAGCGAGTTAGCTGAACAGATTGATGAGAGCCAATTTGAAAAAGTCGTAGCTGTCGGCCCTTACATCAAT
TTTTTCCTTGATAAAGCTAAGATTTCCTCACAGGTCCTTGAACAAGTGATTACAGCAGGTTCAGACTATGCTCAGCAAGA
CGAAGGTCAAGGGCGAAATGTTGCTATTGATATGTCAAGCCCAAACATTGCTAAACCATTTTCAATCGGTCACCTTCGCT
CAACAGTTATTGGTGATAGTCTCGCTCACATTTTTGCCAAAATGGGTTATCAACCTGTAAAAATCAATCACCTTGGTGAC
TGGGGTAAACAATTTGGTATGCTCATTGTTGCCTATAAAAAATGGGGAGACGAAGCTGCTGTTCAGGCACATCCTATTGA
TGAACTCTTAAAACTTTACGTTCGTATCAATGCTGAAGCTGAAACTGATCCAACCGTCGATGAAGAAGCTCGTGAATGGT
TCCGTAAATTGGAAGATGGCGACAAAGAAGCTACCGAATTATGGCAATGGTTCCGTGATGAGAGTTTGCTTGAGTTTAAC
CGTCTTTATGACCAATTACATGTCACCTTCGATAGTTACAACGGTGAGGCCTTCTATAATGACAAAATGGATGAGGTTCT
TGAGCTATTAGAAGCGAAAAACCTTCTTGTAGAATCCAAAGGTGCCCAAGTTGTTAACCTTGAAAAATACGGCATTGAAC
ACCCTGCCTTGATCAAAAAATCAGATGGCGCTACTCTTTACATTACCCGTGACCTAGCTGCCGCACTTTACCGTAAACGC
ACTTATGACTTTGCTAAATCCGTTTATGTTGTTGGTAATGAGCAAGCTGCTCACTTCAAACAGTTAAAAGCAGTGCTACA
AGAAATGGGTTACGATTGGTCAGATGATATGACACACGTTGCTTTTGGACTTGTCACAAAAGGCGGTGCTAAATTATCAA
CACGTAAAGGTAATGTTATTCTTCTTGAACCTACGGTTGCTGAAGCCATTAACCGCGCTGCTTCTCAAATTGAAGCGAAA
AATCCAAATCTTGCTGATAAAGAAGCTGTTGCACACGCTGTTGGTGTCGGTGCCATCAAGTTTTACGATCTCAAAACAGA
TCGTATGAATGGGTATGACTTTGACCTTGAAACCATGGTTTCCTTTGAAGGAGAAACTGGACCTTATGTTCAATACGCTC
ACGCTCGTATCCAATCTATTCTACGTAAAGCTGACTTTACGCCATCTGCAACCACCACTTACAGTTTAGCTGATGCTGAA
AGCTGGGAAATTATCAAACTTATCCAAGATTTCCCACGCATTATCAAGCGAACATCAGATAACTTTGAGCCTTCTATTAT
GGCTAAATTTGCTATTAACTTAGCCCAAAGCTTTAACAAATATTATGCTCACACTCGCATTCTTGACGACAACTCAGAAC
GTGATAACCGCTTAGCTCTCTGCTATGCAACTGCTACTGTTCTTAAAGAAGCGCTTCGCTTACTCGGTGTTGACGCACCA
AATGAAATGTAA

Upstream 100 bases:

>100_bases
ATTTCCTTGAAAGTTTCAGTATAATTTATCAATCCTCTCCTCGTTTATTTTAAAGAAATATGTTAGAATAGGGTGACAAA
CAATTTTTAGGAGACGCTGT

Downstream 100 bases:

>100_bases
GTAATAACATCACTAAGGCTGTCACATTTATGACAGTCTTAGTTTTTTATATTATAATAATAGCACAATATGTTACAGGA
GAATGCCATGCCATCAGAAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFSLAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYIN
FFLDKAKISSQVLEQVITAGSDYAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYQPVKINHLGD
WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLEDGDKEATELWQWFRDESLLEFN
RLYDQLHVTFDSYNGEAFYNDKMDEVLELLEAKNLLVESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKR
TYDFAKSVYVVGNEQAAHFKQLKAVLQEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINRAASQIEAK
NPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLETMVSFEGETGPYVQYAHARIQSILRKADFTPSATTTYSLADAE
SWEIIKLIQDFPRIIKRTSDNFEPSIMAKFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAP
NEM

Sequences:

>Translated_563_residues
MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFSLAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYIN
FFLDKAKISSQVLEQVITAGSDYAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYQPVKINHLGD
WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLEDGDKEATELWQWFRDESLLEFN
RLYDQLHVTFDSYNGEAFYNDKMDEVLELLEAKNLLVESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKR
TYDFAKSVYVVGNEQAAHFKQLKAVLQEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINRAASQIEAK
NPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLETMVSFEGETGPYVQYAHARIQSILRKADFTPSATTTYSLADAE
SWEIIKLIQDFPRIIKRTSDNFEPSIMAKFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAP
NEM
>Mature_563_residues
MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFSLAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYIN
FFLDKAKISSQVLEQVITAGSDYAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYQPVKINHLGD
WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLEDGDKEATELWQWFRDESLLEFN
RLYDQLHVTFDSYNGEAFYNDKMDEVLELLEAKNLLVESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKR
TYDFAKSVYVVGNEQAAHFKQLKAVLQEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINRAASQIEAK
NPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLETMVSFEGETGPYVQYAHARIQSILRKADFTPSATTTYSLADAE
SWEIIKLIQDFPRIIKRTSDNFEPSIMAKFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAP
NEM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=531, Percent_Identity=35.0282485875706, Blast_Score=312, Evalue=4e-85,
Organism=Homo sapiens, GI15149476, Length=585, Percent_Identity=30.7692307692308, Blast_Score=238, Evalue=1e-62,
Organism=Escherichia coli, GI1788184, Length=538, Percent_Identity=34.2007434944238, Blast_Score=278, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=29.5798319327731, Blast_Score=212, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI71985068, Length=571, Percent_Identity=29.2469352014011, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17532153, Length=494, Percent_Identity=26.5182186234818, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320548, Length=579, Percent_Identity=34.7150259067358, Blast_Score=354, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6321883, Length=583, Percent_Identity=33.2761578044597, Blast_Score=353, Evalue=4e-98,
Organism=Drosophila melanogaster, GI18859963, Length=586, Percent_Identity=29.5221843003413, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28571570, Length=468, Percent_Identity=32.2649572649573, Blast_Score=220, Evalue=3e-57,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 63165; Mature: 63165

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFSLAKVLRKAPQMIASEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSDYAQQDEGQGRNVAIDMSS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEECCC
PNIAKPFSIGHLRSTVIGDSLAHIFAKMGYQPVKINHLGDWGKQFGMLIVAYKKWGDEAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCEEEEEEECCCCCCC
VQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLEDGDKEATELWQWFRDESLLEFN
EECCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
RLYDQLHVTFDSYNGEAFYNDKMDEVLELLEAKNLLVESKGAQVVNLEKYGIEHPALIKK
HHHHHHEEEEECCCCCEEECCCHHHHHHHHHHHHHHEECCCCCEEEHHHHCCCCCCEEEE
SDGATLYITRDLAAALYRKRTYDFAKSVYVVGNEQAAHFKQLKAVLQEMGYDWSDDMTHV
CCCCEEEEEHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHH
AFGLVTKGGAKLSTRKGNVILLEPTVAEAINRAASQIEAKNPNLADKEAVAHAVGVGAIK
HHHHHCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEE
FYDLKTDRMNGYDFDLETMVSFEGETGPYVQYAHARIQSILRKADFTPSATTTYSLADAE
EEEEECCCCCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
SWEIIKLIQDFPRIIKRTSDNFEPSIMAKFAINLAQSFNKYYAHTRILDDNSERDNRLAL
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEE
CYATATVLKEALRLLGVDAPNEM
EHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFSLAKVLRKAPQMIASEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSDYAQQDEGQGRNVAIDMSS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEECCC
PNIAKPFSIGHLRSTVIGDSLAHIFAKMGYQPVKINHLGDWGKQFGMLIVAYKKWGDEAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCEEEEEEECCCCCCC
VQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLEDGDKEATELWQWFRDESLLEFN
EECCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
RLYDQLHVTFDSYNGEAFYNDKMDEVLELLEAKNLLVESKGAQVVNLEKYGIEHPALIKK
HHHHHHEEEEECCCCCEEECCCHHHHHHHHHHHHHHEECCCCCEEEHHHHCCCCCCEEEE
SDGATLYITRDLAAALYRKRTYDFAKSVYVVGNEQAAHFKQLKAVLQEMGYDWSDDMTHV
CCCCEEEEEHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHH
AFGLVTKGGAKLSTRKGNVILLEPTVAEAINRAASQIEAKNPNLADKEAVAHAVGVGAIK
HHHHHCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEE
FYDLKTDRMNGYDFDLETMVSFEGETGPYVQYAHARIQSILRKADFTPSATTTYSLADAE
EEEEECCCCCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
SWEIIKLIQDFPRIIKRTSDNFEPSIMAKFAINLAQSFNKYYAHTRILDDNSERDNRLAL
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEE
CYATATVLKEALRLLGVDAPNEM
EHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA