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The map label for this gene is 94995260

Identifier: 94995260

GI number: 94995260

Start: 1824331

End: 1825230

Strand: Direct

Name: 94995260

Synonym: MGAS10750_Spy1864

Alternate gene names: NA

Gene position: 1824331-1825230 (Clockwise)

Preceding gene: 94995259

Following gene: 94995261

Centisome position: 94.18

GC content: 44.56

Gene sequence:

>900_bases
ATGGCAAAAATTGTTGAATGTATTCCTAACTTCTCAGAAGGCCAAAATCAGGCTGTTATCGATGGTTTGGTAGCGACGGC
CAAAAGTATTCCTGGAGTGACCCTTCTCGACTACTCTTCTGATGCGAGCCACAACCGGAGCGTGTTTACCTTGGTTGGAG
ATGACCAGTCTATTCAAGAAGCAGCTTTCCAACTGGTGAAATACGCTTCTGAAAACATTGATATGACCAAACATCATGGC
GAACACCCTCGTATGGGAGCAACCGATGTCTGCCCATTCGTTCCGATCAAAGACATCACTACACAAGAATGTGTTGAGAT
TTCCAAACAAGTCGCAGAACGGATTAACCGTGAACTTGGAATCCCAATCTTCCTTTATGAAGATTCTGCCACACGCCCAG
AACGTCAAAACCTGGCCAAAGTCCGTAAAGGACAATTCGAAGGCATGCCAGAAAAACTGTTGGAAGAGGATTGGGCACCT
GACTACGGAGATCGTAAGATTCACCCAACTGCTGGGGTAACTGCCGTTGGTGCTCGCATGCCATTGGTTGCCTTCAATGT
TAATTTGGATACTGACAATATCGACATTGCTCATAAAATTGCGAAAATTATCCGCGGTTCAGGTGGTGGCTACAAATATT
GTAAGGCTATCGGTGTCATGTTAGAAGACCGCCATATTGCCCAAGTCTCCATGAACATGGTTAACTTTGAAAAATGTTCT
CTTTACCGTACTTTTGAAACCATCAAATTTGAAGCGCGTCGCTACGGTGTGAATGTTATTGGTTCTGAAGTCATCGGCTT
AGCGCCAGCCAAGGCCTTAATCGATGTGGCTGAATACTACTTACAAGTTGAGGACTTTGACTACCATAAACAGGTTCTTG
AAAACCATTTGCTAGGTTAG

Upstream 100 bases:

>100_bases
ATTATTTCACTAATAACTGCTAGCTAAAAATGTAAGCGTTATCTAAAGTAGGTAACCTATTCCCTTAATGAGTAACTCAA
TGACATAAAAGGAGATTAAC

Downstream 100 bases:

>100_bases
GAGGTTCTCTATGGGTTTAGTTGATTTAAGCTTAACAGATTTCGCTAAAGTCCTTGGCTCAGATGCCCCTGATCCAGGTG
GTGGTTCTGCTGCTGCTCTC

Product: glutamate formiminotransferase

Products: 5,10-methenyltetrahydrofolate; NH3

Alternate protein names: Glutamate Formimidoyltransferase; Formimidoyltransferase-Cyclodeaminase; Formiminotransferase-Cyclodeaminase; Formiminotransferase Domain Protein; Formiminotransferase-Cyclodeaminase-Related Protein; Formiminotransferase; Formimidoyltetrahydrofolate Cyclodeaminase; Formiminotransferase-Like

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASHNRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHG
EHPRMGATDVCPFVPIKDITTQECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIGVMLEDRHIAQVSMNMVNFEKCS
LYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDVAEYYLQVEDFDYHKQVLENHLLG

Sequences:

>Translated_299_residues
MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASHNRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHG
EHPRMGATDVCPFVPIKDITTQECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIGVMLEDRHIAQVSMNMVNFEKCS
LYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDVAEYYLQVEDFDYHKQVLENHLLG
>Mature_298_residues
AKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASHNRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGE
HPRMGATDVCPFVPIKDITTQECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAPD
YGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIGVMLEDRHIAQVSMNMVNFEKCSL
YRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDVAEYYLQVEDFDYHKQVLENHLLG

Specific function: Unknown

COG id: COG3643

COG function: function code E; Glutamate formiminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI46255035, Length=292, Percent_Identity=41.4383561643836, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI11140815, Length=292, Percent_Identity=41.4383561643836, Blast_Score=261, Evalue=6e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.3.1.4

Molecular weight: Translated: 33291; Mature: 33160

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASHNRSVFTLVGDDQSIQE
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCHHHHH
AAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQECVEISKQVAERINRELG
HHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
IPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAPDYGDRKIHPTAGVTAVGARM
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEECCCCCCEECCCCC
PLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIGVMLEDRHIAQVSMNMVNFEKCS
CEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDVAEYYLQVEDFDYHKQVLENHLLG
HHHHHHHHHHHHHHHCCHHHCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASHNRSVFTLVGDDQSIQE
CCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCHHHHH
AAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQECVEISKQVAERINRELG
HHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
IPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAPDYGDRKIHPTAGVTAVGARM
CEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCEECCCCCCEECCCCC
PLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIGVMLEDRHIAQVSMNMVNFEKCS
CEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDVAEYYLQVEDFDYHKQVLENHLLG
HHHHHHHHHHHHHHHCCHHHCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-formimidoyltetrahydrofolate

Specific reaction: 5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA