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The map label for this gene is dppC [H]

Identifier: 94995195

GI number: 94995195

Start: 1754158

End: 1754979

Strand: Direct

Name: dppC [H]

Synonym: MGAS10750_Spy1799

Alternate gene names: 94995195

Gene position: 1754158-1754979 (Clockwise)

Preceding gene: 94995194

Following gene: 94995196

Centisome position: 90.56

GC content: 39.42

Gene sequence:

>822_bases
ATGATATTGAAACGTCGAACGATGGTTTTATGGCAACTAGGTATCGCCATTTCTCTCATTCTTAGTATTCTAGCCTTAAA
TCTTTATTTCTATAGGACGCCTTTGGAAACCAATGCAGCTTTACGCAACCTCGCTCCTTCATTAAACCATCTTTTTGGAA
CAGATGGTTTAGGTAGGGATATGTTTGTCAGAACGATTAAAGGGCTTTATTTCTCTTTACAAGTCGGCTTATTAGGTGCC
CTTATGGGAGTCTTTCTTGCGACCGTTTTTGGAGTGCTTGCAGGTCTAGGAAATAGCTTTATTGATAAAATAATAGCCTG
GTTGGTTGATTTGTTTATTGGTATGCCTCATTTGATTTTTATGATTCTCATTTCTTTTGTTGTTGGGAAAGGGGCTCAAG
GGGTTATCATTGCAACAGCTGTTACCCATTGGCCCTCTCTAGCAAGGCTTATCCGCAATGAAGTCTATGATCTAAAGAAT
AAAGCCTTTGTCCAGCTCTCTAAAAGCATGGGAAAAACGCCTTATTATATTGTGAGGCATCATATCCTGCCTTTGATTGC
TTCTCAAATTTTCATTGGGTTTATCCTCTTATTTCCGCACGTCATCTTGCATGAAGCATCCATGACTTTCTTAGGATTTG
GCCTTTCTGCCGAACAACCTTCGGTTGGTATCATTTTGTCAGAGGCAGCTAAGCATATCTCTCTTGGCAATTGGTGGTTG
GTGATTTTTCCAGGCCTTTATCTTATTTTGGTTGTCAATGCCTTTGATACTATCGGAGAATCTTTAAAGAAACTCTTTTA
CCCTCAAACGGATCATTTTTAG

Upstream 100 bases:

>100_bases
TTCTAGCTATCGTGATGATAGGAACATTATTTGTTTTTGCGGGCAATCTTATTGCGGACATTTTAAATAGCATCATCAAT
CCACAGTTAAGGAGAAAAGT

Downstream 100 bases:

>100_bases
GAGGTAGAGATATGACAGAAACATTATTAAGCATTAAAGACCTCTCCATCACCTTCACTCAATACGGAAGATTTTTAAAA
CCATTTCAATCCACACCGAT

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGA
LMGVFLATVFGVLAGLGNSFIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWL
VIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF

Sequences:

>Translated_273_residues
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGA
LMGVFLATVFGVLAGLGNSFIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWL
VIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>Mature_273_residues
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGA
LMGVFLATVFGVLAGLGNSFIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWL
VIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=227, Percent_Identity=33.4801762114537, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=30.6122448979592, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787760, Length=239, Percent_Identity=27.1966527196653, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787498, Length=236, Percent_Identity=30.9322033898305, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789964, Length=223, Percent_Identity=29.5964125560538, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=30, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787549, Length=218, Percent_Identity=22.0183486238532, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30371; Mature: 30371

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377; 3145906 [H]