| Definition | Streptococcus pyogenes MGAS10750 chromosome, complete genome. |
|---|---|
| Accession | NC_008024 |
| Length | 1,937,111 |
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The map label for this gene is iap [H]
Identifier: 94995088
GI number: 94995088
Start: 1631245
End: 1633824
Strand: Direct
Name: iap [H]
Synonym: MGAS10750_Spy1692
Alternate gene names: 94995088
Gene position: 1631245-1633824 (Clockwise)
Preceding gene: 94995087
Following gene: 94995089
Centisome position: 84.21
GC content: 30.47
Gene sequence:
>2580_bases ATGGATAAAAAACTAAAAAAAGATTTTCAAAAGAAAATTATACGAAATAGGGACGCTCCTGAAAAGAATATGGATAGTAA ACTTGTTCATTCAGATGATTATACCAATAAGATTATTAAGAATAAGGATAGGTTCGGAGATAAAATTTCAGAAAAAGAAT CTAAACTTATTCATGAGAATGTATTAGCTAAAGATCAAAAACAAGATAAACTAAAAGATTTTCAGAAGGCTAAAAACAAG GAAAGAATTAGAAAAGAAGTTTTAGATAATAAGAATAAGGCTGAAGAAACAAAACAAACTAATCTTGAAATAAGGACAGA TGAAAGCTATAAACTTGATGAAGAGTTAGATGTAGACATCAAAAAGGTGAATTTTGATAGTGAAAATAGTAGAAATATTA ATTCTAATAAATTAACAACAGATGATATTTCAGCTAAGGCTCAACCAATAAGCAATAAGAAGTCATCAAGTAAAAGACAA GTTCTTAAAAATTATGAGAATAAATTTATCCATAGTAAGGATAAATTCCAAGACAAGATCAACGAGAGAGAGTCTAAGCG AATTCACACAAGTGAAGATAAACCTATTGAAGCAAAGAAAAGTAAGAGAATATATAGAAAAGATAAGCTTGTTAAAGATG AAGTAAGTAAGAACGAAAGTAATGCTAATATCGATAAAAAGCAAAAGCAGAAGCTTTATCAAGAAAAGAGGTTTAGAGAT AAGGAAAAAATTTCTAAAGAGATAGATAAAGAAAGTAAGCTAAGCGAAGTTGATACAGATAAAACTTTTGATAACCCTGA GTTTAAAGACAATAATCTTGAATTTATAAAAGATGAAAAGGAAACAAGCCTTAAACCTTCAGAACAAAAGAAAGTTAATA AAAAGAAGACTTACTACAAAAGAAAAAATTATGAAAGTGATAAATTCACTCGTAAGAAAATCGATGACTTAAAAAACGAA TCTAAGAAAGTTTCAACGAAAGATTCTAAGAAGGCACAAGATGTTAAAGATTTTATCTCAGATAAAAAGATTGGAGAGCT TGAAAAGTCTAAAAGTAAGCTAAAGGATAATATTATAAAGAATAAAACTAAAGGAAGTCTATCTTCTGGGGTTTTATTAT CTGGAGCTAAGTCTTCAGAGTTAGTGAGAGATTATTTAAGTTCAGGATCTGATAATACTGGTGTAGAATCTGGAGAAAAG GCCGCTAATGTAAGCTCTAAACTTCAGCATGGAATAAGGAAGTATAAGTTATACAAAAAGAAAAAGTCATTAAAAAAGCT ATCTACACTTGATAAGAAAATAAGAAATAGAAAAAGCAAGTTGGAGTTTAAAAGTGGCTTGGAAGATTTAAAAAAGTCAG ACTCCTATATAAAGAAAAATAGATTTAAGAAGTTTTACCAAAGAAAACAAATGAAAAGCATGATAGCTAAAAAGCACGAA ACAAGACTGGTAGATAGAGTTAAAAAAGCTATTTTAAGTTTAGGTAAGGCTTCTAAAGAGCTAATCGTAAGAAAAAGTAA GATGGTTCTATTTCTAGTAATAGGACTAGGTCTTATGCTATCAATCATGATTGGTGGTGGAAGTGTTGGTATGAGTGGAT TAAGTAACTCTGTTAACTCAGTAATGACAACAACATACCTATCACAAGATACAGTTCTAAGTGAAGTTAATCAAGAATTT TCATCAATGGAGTATGACCTACAATCACAAATCGAAAGTGTAAAAACAAGTCATCCTGGATATGACGAATATATTATAAA TAAAGATGGAGAAATTGGTCATAATACCCATGAACTTTTATCCTATATAACTTCAAGATGTGGTGAAGTAAAATCAGCAT CTGAAGTAAAAGGAATTTTAAAAGAGCTTTTCGATAAAATGTATAAGCTTGATTTTAAGGAAGAAATCGAAATTAGAACA AGAACAGTAGAAAGAACTAGATATGATAGTCGTGGTAATCCCTATACTAGCTATGAAAAAGAAGAGTACGAATATAAAAA GTTAATTGTAACTTTAAAGAAAAGAGAAATGGATGAAGTTGTTAGGGAAATATTTAAAGATTATCCAGACAATGTAGTTC ATTATGAAGCTCTTCTTGAAGCTAAGGGAAATATGGGAGATGTTTTTGGATCAGGTAATGGGGACTTAGGAGAAATAGTA GATAATCCAAACTTTGGAAATCCTGGTCTTGCTTTTGATTCAGCTACTGCCAAAGCCTTATTTAATGAAGCAGAAAAACA TATAGGCAAAAGATATGTGTTTGGAGCAAGTGGACCATCTAACTTTGACTGCTCAGGTTTTGTATGTTGGTCATTTACAA AGTCTGGTGTAAAGAGAATGCCAAGAACAACTGCATGGAGAATATACAAAGACTATTGTAACCCAGTCAGTCCAAGTGAA GCTCAACCTGGAGATATTATATTTTTCCATTCAACATATAACAGTGGAACACCAATATCTCACGTAGGAATATACGCAGG TAATGGAATGATGATTCACGCAGGAGATCCAATTCAATACACATCAATAAATTCAAAATATTGGAAATCACACTTTTATG GTTTTGGAAGACCTAGATAG
Upstream 100 bases:
>100_bases TTTGGAAATACTATTGTTCCATTTATAGATAAATTCCCTAAAGACACCATGCTATATAAGCTAATGACAACAAAACCAGA AGAAGCTAAGTAGGTGTGAT
Downstream 100 bases:
>100_bases AAGGGAGATATTATGTGAACAGGAAGCTTATAAGTATTAGAAACAAAAAGAAAAAAATAGAAGAGAAATTAAAAGATTTA AATGCAAAATACAAGGAAAT
Product: NlpC/P60 family protein
Products: NA
Alternate protein names: Invasion-associated protein [H]
Number of amino acids: Translated: 859; Mature: 859
Protein sequence:
>859_residues MDKKLKKDFQKKIIRNRDAPEKNMDSKLVHSDDYTNKIIKNKDRFGDKISEKESKLIHENVLAKDQKQDKLKDFQKAKNK ERIRKEVLDNKNKAEETKQTNLEIRTDESYKLDEELDVDIKKVNFDSENSRNINSNKLTTDDISAKAQPISNKKSSSKRQ VLKNYENKFIHSKDKFQDKINERESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKNESNANIDKKQKQKLYQEKRFRD KEKISKEIDKESKLSEVDTDKTFDNPEFKDNNLEFIKDEKETSLKPSEQKKVNKKKTYYKRKNYESDKFTRKKIDDLKNE SKKVSTKDSKKAQDVKDFISDKKIGELEKSKSKLKDNIIKNKTKGSLSSGVLLSGAKSSELVRDYLSSGSDNTGVESGEK AANVSSKLQHGIRKYKLYKKKKSLKKLSTLDKKIRNRKSKLEFKSGLEDLKKSDSYIKKNRFKKFYQRKQMKSMIAKKHE TRLVDRVKKAILSLGKASKELIVRKSKMVLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNSVMTTTYLSQDTVLSEVNQEF SSMEYDLQSQIESVKTSHPGYDEYIINKDGEIGHNTHELLSYITSRCGEVKSASEVKGILKELFDKMYKLDFKEEIEIRT RTVERTRYDSRGNPYTSYEKEEYEYKKLIVTLKKREMDEVVREIFKDYPDNVVHYEALLEAKGNMGDVFGSGNGDLGEIV DNPNFGNPGLAFDSATAKALFNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRMPRTTAWRIYKDYCNPVSPSE AQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQYTSINSKYWKSHFYGFGRPR
Sequences:
>Translated_859_residues MDKKLKKDFQKKIIRNRDAPEKNMDSKLVHSDDYTNKIIKNKDRFGDKISEKESKLIHENVLAKDQKQDKLKDFQKAKNK ERIRKEVLDNKNKAEETKQTNLEIRTDESYKLDEELDVDIKKVNFDSENSRNINSNKLTTDDISAKAQPISNKKSSSKRQ VLKNYENKFIHSKDKFQDKINERESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKNESNANIDKKQKQKLYQEKRFRD KEKISKEIDKESKLSEVDTDKTFDNPEFKDNNLEFIKDEKETSLKPSEQKKVNKKKTYYKRKNYESDKFTRKKIDDLKNE SKKVSTKDSKKAQDVKDFISDKKIGELEKSKSKLKDNIIKNKTKGSLSSGVLLSGAKSSELVRDYLSSGSDNTGVESGEK AANVSSKLQHGIRKYKLYKKKKSLKKLSTLDKKIRNRKSKLEFKSGLEDLKKSDSYIKKNRFKKFYQRKQMKSMIAKKHE TRLVDRVKKAILSLGKASKELIVRKSKMVLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNSVMTTTYLSQDTVLSEVNQEF SSMEYDLQSQIESVKTSHPGYDEYIINKDGEIGHNTHELLSYITSRCGEVKSASEVKGILKELFDKMYKLDFKEEIEIRT RTVERTRYDSRGNPYTSYEKEEYEYKKLIVTLKKREMDEVVREIFKDYPDNVVHYEALLEAKGNMGDVFGSGNGDLGEIV DNPNFGNPGLAFDSATAKALFNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRMPRTTAWRIYKDYCNPVSPSE AQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQYTSINSKYWKSHFYGFGRPR >Mature_859_residues MDKKLKKDFQKKIIRNRDAPEKNMDSKLVHSDDYTNKIIKNKDRFGDKISEKESKLIHENVLAKDQKQDKLKDFQKAKNK ERIRKEVLDNKNKAEETKQTNLEIRTDESYKLDEELDVDIKKVNFDSENSRNINSNKLTTDDISAKAQPISNKKSSSKRQ VLKNYENKFIHSKDKFQDKINERESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKNESNANIDKKQKQKLYQEKRFRD KEKISKEIDKESKLSEVDTDKTFDNPEFKDNNLEFIKDEKETSLKPSEQKKVNKKKTYYKRKNYESDKFTRKKIDDLKNE SKKVSTKDSKKAQDVKDFISDKKIGELEKSKSKLKDNIIKNKTKGSLSSGVLLSGAKSSELVRDYLSSGSDNTGVESGEK AANVSSKLQHGIRKYKLYKKKKSLKKLSTLDKKIRNRKSKLEFKSGLEDLKKSDSYIKKNRFKKFYQRKQMKSMIAKKHE TRLVDRVKKAILSLGKASKELIVRKSKMVLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNSVMTTTYLSQDTVLSEVNQEF SSMEYDLQSQIESVKTSHPGYDEYIINKDGEIGHNTHELLSYITSRCGEVKSASEVKGILKELFDKMYKLDFKEEIEIRT RTVERTRYDSRGNPYTSYEKEEYEYKKLIVTLKKREMDEVVREIFKDYPDNVVHYEALLEAKGNMGDVFGSGNGDLGEIV DNPNFGNPGLAFDSATAKALFNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRMPRTTAWRIYKDYCNPVSPSE AQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQYTSINSKYWKSHFYGFGRPR
Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]
COG id: COG0791
COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 3 LysM repeats [H]
Homologues:
Organism=Escherichia coli, GI1787944, Length=125, Percent_Identity=40, Blast_Score=80, Evalue=5e-16, Organism=Escherichia coli, GI1786421, Length=117, Percent_Identity=31.6239316239316, Blast_Score=69, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000064 - InterPro: IPR018392 - InterPro: IPR002482 - InterPro: IPR003646 - InterPro: IPR013247 [H]
Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]
EC number: NA
Molecular weight: Translated: 98966; Mature: 98966
Theoretical pI: Translated: 10.16; Mature: 10.16
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKKLKKDFQKKIIRNRDAPEKNMDSKLVHSDDYTNKIIKNKDRFGDKISEKESKLIHEN CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHCCHHHHHHHHHHHHH VLAKDQKQDKLKDFQKAKNKERIRKEVLDNKNKAEETKQTNLEIRTDESYKLDEELDVDI HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCCCCCCCCCEE KKVNFDSENSRNINSNKLTTDDISAKAQPISNKKSSSKRQVLKNYENKFIHSKDKFQDKI EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH NERESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKNESNANIDKKQKQKLYQEKRFRD HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC KEKISKEIDKESKLSEVDTDKTFDNPEFKDNNLEFIKDEKETSLKPSEQKKVNKKKTYYK HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHHH RKNYESDKFTRKKIDDLKNESKKVSTKDSKKAQDVKDFISDKKIGELEKSKSKLKDNIIK HCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH NKTKGSLSSGVLLSGAKSSELVRDYLSSGSDNTGVESGEKAANVSSKLQHGIRKYKLYKK CCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH KKSLKKLSTLDKKIRNRKSKLEFKSGLEDLKKSDSYIKKNRFKKFYQRKQMKSMIAKKHE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TRLVDRVKKAILSLGKASKELIVRKSKMVLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNS HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHH VMTTTYLSQDTVLSEVNQEFSSMEYDLQSQIESVKTSHPGYDEYIINKDGEIGHNTHELL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHH SYITSRCGEVKSASEVKGILKELFDKMYKLDFKEEIEIRTRTVERTRYDSRGNPYTSYEK HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCH EEYEYKKLIVTLKKREMDEVVREIFKDYPDNVVHYEALLEAKGNMGDVFGSGNGDLGEIV HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHC DNPNFGNPGLAFDSATAKALFNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRM CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHC PRTTAWRIYKDYCNPVSPSEAQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQY CCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCEEE TSINSKYWKSHFYGFGRPR ECCCHHHHHHHHCCCCCCC >Mature Secondary Structure MDKKLKKDFQKKIIRNRDAPEKNMDSKLVHSDDYTNKIIKNKDRFGDKISEKESKLIHEN CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHCCHHHHHHHHHHHHH VLAKDQKQDKLKDFQKAKNKERIRKEVLDNKNKAEETKQTNLEIRTDESYKLDEELDVDI HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCCCCCCCCCEE KKVNFDSENSRNINSNKLTTDDISAKAQPISNKKSSSKRQVLKNYENKFIHSKDKFQDKI EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH NERESKRIHTSEDKPIEAKKSKRIYRKDKLVKDEVSKNESNANIDKKQKQKLYQEKRFRD HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC KEKISKEIDKESKLSEVDTDKTFDNPEFKDNNLEFIKDEKETSLKPSEQKKVNKKKTYYK HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHHH RKNYESDKFTRKKIDDLKNESKKVSTKDSKKAQDVKDFISDKKIGELEKSKSKLKDNIIK HCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH NKTKGSLSSGVLLSGAKSSELVRDYLSSGSDNTGVESGEKAANVSSKLQHGIRKYKLYKK CCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH KKSLKKLSTLDKKIRNRKSKLEFKSGLEDLKKSDSYIKKNRFKKFYQRKQMKSMIAKKHE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TRLVDRVKKAILSLGKASKELIVRKSKMVLFLVIGLGLMLSIMIGGGSVGMSGLSNSVNS HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHH VMTTTYLSQDTVLSEVNQEFSSMEYDLQSQIESVKTSHPGYDEYIINKDGEIGHNTHELL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHH SYITSRCGEVKSASEVKGILKELFDKMYKLDFKEEIEIRTRTVERTRYDSRGNPYTSYEK HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCH EEYEYKKLIVTLKKREMDEVVREIFKDYPDNVVHYEALLEAKGNMGDVFGSGNGDLGEIV HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHC DNPNFGNPGLAFDSATAKALFNEAEKHIGKRYVFGASGPSNFDCSGFVCWSFTKSGVKRM CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHC PRTTAWRIYKDYCNPVSPSEAQPGDIIFFHSTYNSGTPISHVGIYAGNGMMIHAGDPIQY CCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCEEE TSINSKYWKSHFYGFGRPR ECCCHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1514809; 1459966 [H]