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The map label for this gene is pepXP [H]

Identifier: 94995031

GI number: 94995031

Start: 1574020

End: 1576302

Strand: Direct

Name: pepXP [H]

Synonym: MGAS10750_Spy1635

Alternate gene names: 94995031

Gene position: 1574020-1576302 (Clockwise)

Preceding gene: 94995030

Following gene: 94995033

Centisome position: 81.26

GC content: 39.82

Gene sequence:

>2283_bases
ATGCGCTATAATCAATTTTCCTATATTCCAACTAGTCTAGAAAGAGCGGCTGAAGAATTAAAAGAATTGGGCTTTGATCT
GGATCTGCAAAAAACTGCCAAAGCTAACCTAGAAAGCTTTTTACGTAAACTCTTCTTCCACTACCCTGATAGTGATTATC
CTTTAAGTCATCTAATCGCCAAAAATGACATGGACGCATTGAGCTTTTTTCAATCAGAGCAAGAGTTATCCAAAGAGGTT
TTTGATTTACTGGCCCTGCAAGTCCTTGGCTTTATTCCTGGAGTTGATTTTACAGAGGCCGATGCTTTCCTTGATAAACT
GGCCTTTCCTATCCACTTTGACGAAACAGAAATTATCAAGCATATCCACCACTTATTAGCGACCCGTTGTAAGTCTGGCA
TGACCCTGATTGATGATTTGGTCAGCCAAGGAATGCTTACTATGGACAATGATTACCACTTCTTCAACGGTAAATCATTA
GCTACCTTTGACACGTCACAGCTGATTCGAGAAGTTGTTTACGTTGAAGCACCTCTTGATACCGATCAAGATGGCCAACT
TGATCTTATTAAGGTTAATATCATTCGTCCTCAATCTCAAAAACCATTACCAACTTTGATGACACCTAGTCCATACCATC
AAGGTATCAATGAAGTAGCCAACGACAAAAAACTTTATCGTATGGAAAAAGAGTTAGTCGTTAAAAAAAGGAGACAAATC
ACTGTCGAAGACAGGGATTTTATTCCTCTTGAGACACAGCCTTGCAAACTTCCTATAGGTCAAAATCTAGAAAGCTTTAG
CTACATTAACTCCTATAGCCTCAACGATTATTTCCTCGCACGTGGGTTTGCTAATATCTATGTTTCAGGTGTGGGAACTG
CTGGTTCCACTGGCTTTATGACGAGTGGAGACTATGCTCAAATTGAAAGCTTTAAAGCCGTTATTGATTGGCTAAATGGA
AGAGCCACAGCCTACACCAGCCACTCAAAAACCCACCAAGTGAGAGCTGATTGGGCAAATGGTCTAGTTTGTACGACTGG
AAAGTCCTACTTGGGAACTATGTCTACTGGTTTAGCCACTACAGGCGTAGACGGATTAGCCATGATTATTGCAGAATCAG
CTATTTCTTCTTGGTATAACTACTACCGCGAAAATGGCTTAGTTTGTAGTCCTGGTGGCTATCCTGGAGAGGATCTAGAT
GTCCTAACTGAGCTCACCTACTCGCGTAATTTATTGGCTGGCGATTATCTTCGCCATAATGATCGTTATCAAGAATTGCT
AAACCAACAGTCTCAGGCGTTAGACCGACAATCTGGTGATTATAATCAATTTTGGCACGACCGCAATTACTTAAAAAATG
CTCATCAAATAAAGTGTGATGTCGTTTATACTCATGGCTTACAAGACTGGAATGTCAAACCAAGACAGGTCTATGAGATT
TTCAATGCGCTTCCTTCCACAATCAACAAGCACCTCTTTTTACATCAAGGTGAGCATGTTTACATGCATAATCGGCAATC
CATTGATTTTCGCGAAAGCATGAATGCCCTTTTATGTCAAAAACTCTTAGGCCTAGCTAATGATTTTAGCCTTCCTGAAA
TGATCTGGCAGGATAACACCTGCCCACAAAACTGGCAGGAGCGTAAAGTCTTTGGAACCTCAACCATCAAAGAGCTTGAC
CTCGGTCAGGAACTGCTTTTAATTGATAATCACTATGGTGAAGATGAATTTAAAGCTTACGGTAAAGATTTCCGTGCGTT
CAAAGCAGCTCTCTTTGAAGGCAAGGCCAATCAAGCCCTGGTTGATATTTTACTGGAAGAGGACTTACCTATTAACGGTG
AAATTGTCCTACAGTTAAAAGTGAAATCAAGTGAAAATAAAGGACTTCTATCTGCACAAATCCTTGACTATGGTAAGAAA
AAACGCTTGGGCGATCTTCCTATTGCTCTCACCCAATCAAGTATTGACAATGGGCAAAATTTCTCTAGAGAATCCCTTAA
AGAGCTACCATTTAGAGAAGATTCTTACCGTGTTATTTCGAAAGGTTTCATGAATTTACAAAATCGCAATAATTTGTCGT
CAATTGAAACTATTCCTAATAATAAATGGATGACTGTTAGACTTCCTTTGCAACCAACCATCTATCATCTAGAAAAAGGA
GATACCCTTCGAGTCATCTTATACACAACCGATTTTGAACATACTGTCCGTGACAACAGCAACTATGCTTTAACTATCGA
TCTCAGTCAGTCTCAATTGATTGTGCCAATAGCATCAAATTAA

Upstream 100 bases:

>100_bases
AAAAAACATCATTCGCATTGATAAACAACATATTATCATTACCAATCTTGATAAATTAAAAGATAATATCGTTTTCTAAG
CCACTAGAAAGGAAACTCCT

Downstream 100 bases:

>100_bases
CAAAGAAAAGTGCTTAGCAATATAACTAAGCACTTTTTTGTTAATTGGTCTTACTAATAGCAAACAGAAAACGATCGTCT
TAGTTCATAAATTCCGAATC

Product: x-prolyl-dipeptidyl aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidyl-peptidase; X-prolyl-dipeptidyl aminopeptidase; X-PDAP [H]

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV
FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNG
RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD
VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
FNALPSTINKHLFLHQGEHVYMHNRQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD
LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQALVDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK
KRLGDLPIALTQSSIDNGQNFSRESLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN

Sequences:

>Translated_760_residues
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV
FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNG
RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD
VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
FNALPSTINKHLFLHQGEHVYMHNRQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD
LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQALVDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK
KRLGDLPIALTQSSIDNGQNFSRESLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
>Mature_760_residues
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEV
FDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNG
RATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLD
VLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
FNALPSTINKHLFLHQGEHVYMHNRQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELD
LGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQALVDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKK
KRLGDLPIALTQSSIDNGQNFSRESLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN

Specific function: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR008252
- InterPro:   IPR000383
- InterPro:   IPR015251 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C; PF09168 PepX_N [H]

EC number: =3.4.14.11 [H]

Molecular weight: Translated: 86714; Mature: 86714

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
KNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCHHHHHH
HIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLD
HHHHHHHHHHHCCCHHHHHHHHCCCEEECCCEEEECCCEEEEECHHHHHHHHHEEECCCC
TDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCE
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCCC
TSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLAT
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCEEEECCCHHHHHHHCCCHH
TGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHN
CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC
DRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
FNALPSTINKHLFLHQGEHVYMHNRQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNT
HHHHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC
CPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQAL
CCCCHHHCEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
VDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQN
HHHHHHCCCCCCCEEEEEEEEECCCCCCCEEHHHHHCCCCCCCCCCCEEEECCCCCCCCC
FSRESLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
CCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCC
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
CEEEEEEEECCCCHHHCCCCCEEEEEEECCCEEEEEECCC
>Mature Secondary Structure
MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIA
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
KNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEECCHHHHHH
HIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLD
HHHHHHHHHHHCCCHHHHHHHHCCCEEECCCEEEECCCEEEEECHHHHHHHHHEEECCCC
TDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQI
CCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCE
TVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCCC
TSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLAT
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCEEEECCCHHHHHHHCCCHH
TGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHN
CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC
DRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEI
HHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHH
FNALPSTINKHLFLHQGEHVYMHNRQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNT
HHHHHHHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCC
CPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQAL
CCCCHHHCEECCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
VDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQN
HHHHHHCCCCCCCEEEEEEEEECCCCCCCEEHHHHHCCCCCCCCCCCEEEECCCCCCCCC
FSRESLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKG
CCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCC
DTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
CEEEEEEEECCCCHHHCCCCCEEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]